LINOPRIL 5mg Tablets

What is LINOPRIL 5mg

LINOPRIL 5 mg is a prescription medication that contains the active ingredient Lisinopril, which belongs to the class of drugs known as ACE (Angiotensin-Converting Enzyme) inhibitors. It is primarily used for the treatment of high blood pressure (hypertension), congestive heart failure, and for improving survival rates following a heart attack. Additionally, it offers kidney protection in diabetic patients with hypertension.

The drug works by relaxing the blood vessels so that blood can flow more easily, helping to reduce blood pressure and decrease the workload on the heart.

• Drug Class: ACE Inhibitor
• Primary Uses: Hypertension, heart failure, post-myocardial infarction management, diabetic nephropathy
• Available Form: Oral tablets (film-coated)

How to use LINOPRIL 5mg

Take LINOPRIL 5 mg exactly as prescribed by your healthcare provider. The medication is typically taken once daily and may be administered with or without food. It’s important to take it at the same time each day for best results.

• Swallow the tablet whole with a glass of water.
• Do not crush or chew the tablet.
• If you miss a dose, take it as soon as you remember. If it’s near the time for your next dose, skip the missed dose.
• Do not double the dose to make up for a missed one.

Continue taking the medication even if you feel well. Do not stop using it without consulting your doctor, as doing so may worsen your condition.

Mode of Action LINOPRIL 5mg

Lisinopril works by inhibiting the action of the angiotensin-converting enzyme (ACE). This enzyme plays a critical role in the body’s renin-angiotensin-aldosterone system (RAAS), which regulates blood pressure.

• Blocks the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor.
• Reduces levels of angiotensin II, resulting in vasodilation (relaxation of blood vessels).
• Lowers secretion of aldosterone, which reduces water and salt retention.
• Improves cardiac output and helps prevent vascular remodeling.

These effects collectively help reduce high blood pressure and ease the heart’s workload.

LINOPRIL 5mg Interactions LINOPRIL 5mg

LINOPRIL 5 mg may interact with other medications, which can alter its effects or increase the risk of side effects. Be sure to inform your healthcare provider of all medications you are taking.

• Diuretics: May intensify the risk of hypotension or dehydration.
• NSAIDs (e.g., ibuprofen): May reduce antihypertensive effect and impair renal function.
• Potassium supplements or potassium-sparing diuretics: May increase risk of hyperkalemia.
• Antidiabetic agents (insulin, sulfonylureas): Risk of enhanced hypoglycemic effects.
• Lithium: Increased risk of lithium toxicity.

Avoid alcohol while on LINOPRIL as it may amplify the blood pressure–lowering effects.

Dosage of LINOPRIL 5mg

The starting dose of LINOPRIL 5 mg varies depending on the condition being treated. It is commonly used as a low initial dose and may be adjusted gradually under medical supervision.

• Hypertension: Initial dose usually 5–10 mg daily; maintenance dose 20–40 mg daily.
• Heart Failure: Starting dose 2.5–5 mg daily; adjusted based on tolerance.
• Post-Heart Attack: 5 mg initially, followed by a maintenance dose of 10 mg daily.
• Renal Impairment: Dose adjustment is necessary; start low and monitor renal function.

Never change the dose without consulting your physician.

Possible side effects of LINOPRIL 5mg

While most people tolerate LINOPRIL 5 mg well, some may experience side effects. Inform your doctor if any symptoms persist or worsen.

• Common: Cough, dizziness, headache, fatigue
• Less Common: Nausea, rash, loss of taste, diarrhea
• Serious: Angioedema (swelling of lips/tongue), kidney dysfunction, high potassium
• Rare: Liver enzyme elevations, allergic skin reactions

Seek immediate medical attention if you experience swelling of the face or throat, difficulty breathing, or symptoms of severe allergic reactions.

LINOPRIL 5mg Contraindications LINOPRIL 5mg

LINOPRIL should not be used in the following conditions:

• History of angioedema related to previous ACE inhibitor use
• Known hypersensitivity to lisinopril or other ACE inhibitors
• Pregnancy (especially in the second and third trimester)
• Severe bilateral renal artery stenosis
• Concomitant use with aliskiren in diabetic patients

Use with caution in patients with impaired renal function, hyperkalemia, or low sodium levels.

Storage of LINOPRIL 5mg

• Store at a temperature between 15°C and 30°C (59°F – 86°F)
• Keep in original packaging to protect from moisture and light
• Do not store in the bathroom or near heat sources
• Keep out of reach of children

Do not use after the expiry date printed on the packaging. Dispose of unused medication in accordance with local regulations.