LIDOCATON 2% 1:80000 Injection/Solution for

What is LIDOCATON 2% 1:80000

LIDOCATON 2% 1:80000 is a local anesthetic injection that combines two active ingredients: Lidocaine Hydrochloride and Adrenaline (Epinephrine). It is designed for use in a variety of local anesthesia applications, such as dental procedures, minor surgeries, or nerve blocks. The formulation is available in a 1.8 mL cartridge and is typically used in clinical settings, ensuring effective numbing with reduced bleeding during procedures.

• Generic Name: Lidocaine Hydrochloride + Adrenaline (Epinephrine)
• Concentration: 2% Lidocaine (20 mg/mL) and 1:80000 Adrenaline
• Form: Injectable solution
• Size: 1.8 mL per cartridge, with 50 cartridges (10 per blister pack x 5)
• Uses: Local infiltration anesthesia, dental blocks, nerve blocks, and minor surgical procedures

The 2% concentration of Lidocaine offers rapid and reliable anesthesia by blocking sodium channels in nerve cells. The addition of Adrenaline (1:80000 concentration) helps to constrict blood vessels in the area, minimizing bleeding during procedures and prolonging the effect of lidocaine by reducing its absorption into the bloodstream. This combination provides effective localized anesthesia while minimizing systemic exposure.

LIDOCATON 2% 1:80000 is ideal for surgical and dental procedures requiring quick, reliable, and extended anesthesia. The 1.8 mL cartridge packaging allows for easy use in clinical settings, making it a go-to choice for healthcare professionals.

How to use LIDOCATON 2% 1:80000

LIDOCATON 2% 1:80000 should be administered only by healthcare professionals trained in injection techniques. The following steps outline the safe and effective use of this injectable anesthetic:

• Route of Administration: The solution is typically administered via local infiltration, nerve blocks, or other regional anesthesia techniques. It is not intended for intravenous administration.
• Preparation: Before use, visually inspect the cartridge for any discoloration or particulate matter. Only administer the solution if it is clear and free from any foreign particles.
• Injection Technique: Use the appropriate syringe or cartridge injector to administer the solution. Ensure slow and steady injection to avoid rapid systemic absorption, which could lead to toxicity.
• Local Infiltration: Inject directly into the tissue surrounding the surgical area. Careful injection technique helps to minimize the risk of complications.
• Nerve Blocks: Accurate needle placement is critical. Utilize anatomical landmarks or guided imaging for nerve blocks to ensure effective anesthesia and minimize the risk of complications.

Proper dose administration is crucial to avoid systemic toxicity. The dosage varies depending on the procedure, patient size, and the location being treated. Adrenaline prolongs the anesthetic effect, reducing the need for additional doses during short procedures. Always monitor the patient during and after administration for adverse effects.

Mode of Action LIDOCATON 2% 1:80000

LIDOCATON 2% 1:80000 works by leveraging the combined action of Lidocaine and Adrenaline to provide effective local anesthesia with extended duration and reduced bleeding.

• Lidocaine (2%): Lidocaine is an amide-type local anesthetic that works by blocking sodium channels on the nerve cell membranes. This prevents depolarization and transmission of nerve impulses, effectively numbing the targeted area. The onset of action is rapid, typically within 2-5 minutes, and the duration of anesthesia lasts for 1-2 hours, depending on the area and dosage.
• Adrenaline (Epinephrine): Adrenaline constricts local blood vessels, which reduces blood flow to the site of injection. This results in decreased bleeding during procedures and slows the absorption of lidocaine into the bloodstream, thereby prolonging the anesthetic effect. It also reduces the likelihood of systemic toxicity by limiting the spread of lidocaine beyond the injection site.

The combination of lidocaine and adrenaline provides a highly effective method of local anesthesia for various procedures. The lidocaine delivers the anesthetic effect, while the adrenaline enhances its action by improving hemostasis and prolonging the numbing effect.

LIDOCATON 2% 1:80000 Interactions LIDOCATON 2% 1:80000

LIDOCATON 2% 1:80000 may interact with several other medications, which could either potentiate or diminish its effects. It's essential to be aware of these interactions to ensure patient safety during anesthesia administration.

• Beta-blockers (e.g., propranolol): These medications can slow the metabolism of lidocaine, potentially increasing the risk of toxicity. Adrenaline may also amplify the effects of beta-blockers, leading to heightened bradycardia or hypotension.
• Other Local Anesthetics: Co-administration of multiple local anesthetics increases the risk of systemic toxicity. Always ensure that only one anesthetic is used for a procedure to avoid complications.
• Monoamine Oxidase Inhibitors (MAOIs): MAOIs can potentiate the effects of adrenaline, leading to increased blood pressure and risk of hypertensive crisis. Avoid using LIDOCATON in patients on MAOIs or monitor closely.
• Tricyclic Antidepressants (e.g., amitriptyline): These medications may increase the risk of arrhythmias when used with lidocaine. The combination may also increase the likelihood of increased blood pressure due to the presence of adrenaline.
• CNS Depressants (e.g., benzodiazepines, opioids): Concurrent use with CNS depressants can increase the risk of sedation, dizziness, and CNS toxicity. Monitoring for these side effects is important, particularly in elderly or frail patients.

Patients should always inform their healthcare provider about all current medications, including over-the-counter drugs, to prevent harmful drug interactions and ensure safe use of LIDOCATON 2% 1:80000.

Dosage of LIDOCATON 2% 1:80000

The dosage of LIDOCATON 2% 1:80000 should be tailored to the individual patient, depending on the procedure being performed, the patient's age, weight, and medical history. Generally, the following guidelines can help determine the appropriate dose:

• Maximum Dosage for Adults (Lidocaine): The maximum dose of lidocaine should not exceed 4.5 mg/kg body weight (approximately 300 mg for a 70 kg adult). The dose should be reduced in elderly patients or those with impaired cardiovascular function.
• Common Dosages:
• For dental procedures: 1-3 mL
• For minor surgical procedures or local infiltration: 5-10 mL depending on the area to be anesthetized
• Nerve blocks: 5-20 mL depending on the nerve and the required block

Adrenaline helps to extend the effects of lidocaine, so the total amount of lidocaine administered can be slightly higher with the addition of adrenaline. Always ensure the dosage is appropriate for the clinical situation, as too much lidocaine can lead to toxicity and adverse effects.

Possible side effects of LIDOCATON 2% 1:80000

While LIDOCATON 2% 1:80000 is generally safe when administered properly, side effects can occur, especially in cases of overdose or hypersensitivity. These side effects can range from mild reactions to severe complications.

• Common Side Effects:
• Pain or swelling at the injection site
• Temporary numbness or tingling
• Minor redness or irritation
• CNS Reactions:
• Dizziness, restlessness, or confusion
• Severe cases may lead to seizures, particularly in high doses
• Cardiovascular Reactions:
• Bradycardia (slow heart rate)
• Hypotension (low blood pressure)
• Rarely, arrhythmias or other cardiac irregularities, especially in patients with preexisting heart conditions
• Allergic Reactions:
• Skin rash, itching, or hives
• Shortness of breath, wheezing, or bronchospasm
• Severe anaphylaxis in rare cases

If any severe side effects occur, such as difficulty breathing or a sudden change in heart rate, seek medical attention immediately.

Contraindications of LIDOCATON 2% 1:80000

LIDOCATON 2% 1:80000 is contraindicated in several situations to avoid adverse effects. These include:

• Hypersensitivity: Patients with known allergies to lidocaine or epinephrine should avoid this product.
• Severe Heart Conditions: Patients with second or third-degree heart block or those with untreated arrhythmias should not use this medication without prior medical consultation.
• Severe Hypertension: Due to the vasoconstrictive effects of adrenaline, it is contraindicated in patients with uncontrolled high blood pressure.
• Pregnancy: Use in pregnant women should be limited to situations where the benefits outweigh the potential risks, especially in the first trimester.

Storage of LIDOCATON 2% 1:80000

Proper storage is critical to maintaining the stability and effectiveness of LIDOCATON 2% 1:80000.

• Temperature: Store at room temperature, between 15°C and 30°C (59°F to 86°F). Do not freeze.
• Light Protection: Keep the solution in its original packaging to protect it from light exposure, which may degrade the product.

• While LIDOCATON 2% 1:80000 is generally safe when administered properly, side effects can occur, especially in cases of overdose or hypersensitivity. These side effects can range from mild reactions to severe complications.

  • Common Side Effects:
  • Pain or swelling at the injection site
  • Temporary numbness or tingling
  • Minor redness or irritation
  • CNS Reactions:
  • Dizziness, restlessness, or confusion
  • Severe cases may lead to seizures, particularly in high doses
  • Cardiovascular Reactions:
  • Bradycardia (slow heart rate)
  • Hypotension (low blood pressure)
  • Rarely, arrhythmias or other cardiac irregularities, especially in patients with preexisting heart conditions
  • Allergic Reactions:
  • Skin rash, itching, or hives
  • Shortness of breath, wheezing, or bronchospasm
  • Severe anaphylaxis in rare cases

  If any severe side effects occur, such as difficulty breathing or a sudden change in heart rate, seek medical attention immediately.

  Contraindications of LIDOCATON 2% 1:80000

  LIDOCATON 2% 1:80000 is contraindicated in several situations to avoid adverse effects. These include:

  • Hypersensitivity: Patients with known allergies to lidocaine or epinephrine should avoid this product.
  • Severe Heart Conditions: Patients with second or third-degree heart block or those with untreated arrhythmias should not use this medication without prior medical consultation.
  • Severe Hypertension: Due to the vasoconstrictive effects of adrenaline, it is contraindicated in patients with uncontrolled high blood pressure.
  • Pregnancy: Use in pregnant women should be limited to situations where the benefits outweigh the potential risks, especially in the first trimester.

  Storage of LIDOCATON 2% 1:80000

  Proper storage is critical to maintaining the stability and effectiveness of LIDOCATON 2% 1:80000.

  • Temperature: Store at room temperature, between 15°C and 30°C (59°F to 86°F). Do not freeze.
  • Light Protection: Keep the solution in its original packaging to protect it from light exposure, which may degrade the product.

  • While LIDOCATON 2% 1:80000 is generally safe when administered properly, side effects can occur, especially in cases of overdose or hypersensitivity. These side effects can range from mild reactions to severe complications.

    • Common Side Effects:
    • Pain or swelling at the injection site
    • Temporary numbness or tingling
    • Minor redness or irritation
    • CNS Reactions:
    • Dizziness, restlessness, or confusion
    • Severe cases may lead to seizures, particularly in high doses
    • Cardiovascular Reactions:
    • Bradycardia (slow heart rate)
    • Hypotension (low blood pressure)
    • Rarely, arrhythmias or other cardiac irregularities, especially in patients with preexisting heart conditions
    • Allergic Reactions:
    • Skin rash, itching, or hives
    • Shortness of breath, wheezing, or bronchospasm
    • Severe anaphylaxis in rare cases

    If any severe side effects occur, such as difficulty breathing or a sudden change in heart rate, seek medical attention immediately.

    Contraindications of LIDOCATON 2% 1:80000

    LIDOCATON 2% 1:80000 is contraindicated in several situations to avoid adverse effects. These include:

    • Hypersensitivity: Patients with known allergies to lidocaine or epinephrine should avoid this product.
    • Severe Heart Conditions: Patients with second or third-degree heart block or those with untreated arrhythmias should not use this medication without prior medical consultation.
    • Severe Hypertension: Due to the vasoconstrictive effects of adrenaline, it is contraindicated in patients with uncontrolled high blood pressure.
    • Pregnancy: Use in pregnant women should be limited to situations where the benefits outweigh the potential risks, especially in the first trimester.

    Storage of LIDOCATON 2% 1:80000

    Proper storage is critical to maintaining the stability and effectiveness of LIDOCATON 2% 1:80000.

    • Temperature: Store at room temperature, between 15°C and 30°C (59°F to 86°F). Do not freeze.
    • Light Protection: Keep the solution in its original packaging to protect it from light exposure, which may degrade the product.

    • While LIDOCATON 2% 1:80000 is generally safe when administered properly, side effects can occur, especially in cases of overdose or hypersensitivity. These side effects can range from mild reactions to severe complications.

      • Common Side Effects:
      • Pain or swelling at the injection site
      • Temporary numbness or tingling
      • Minor redness or irritation
      • CNS Reactions:
      • Dizziness, restlessness, or confusion
      • Severe cases may lead to seizures, particularly in high doses
      • Cardiovascular Reactions:
      • Bradycardia (slow heart rate)
      • Hypotension (low blood pressure)
      • Rarely, arrhythmias or other cardiac irregularities, especially in patients with preexisting heart conditions
      • Allergic Reactions:
      • Skin rash, itching, or hives
      • Shortness of breath, wheezing, or bronchospasm
      • Severe anaphylaxis in rare cases

      If any severe side effects occur, such as difficulty breathing or a sudden change in heart rate, seek medical attention immediately.

      LIDOCATON 2% 1:80000 Contraindications LIDOCATON 2% 1:80000

      While LIDOCATON 2% 1:80000 is generally safe when administered properly, side effects can occur, especially in cases of overdose or hypersensitivity. These side effects can range from mild reactions to severe complications.

      • Common Side Effects:
      • Pain or swelling at the injection site
      • Temporary numbness or tingling
      • Minor redness or irritation
      • CNS Reactions:
      • Dizziness, restlessness, or confusion
      • Severe cases may lead to seizures, particularly in high doses
      • Cardiovascular Reactions:
      • Bradycardia (slow heart rate)
      • Hypotension (low blood pressure)
      • Rarely, arrhythmias or other cardiac irregularities, especially in patients with preexisting heart conditions
      • Allergic Reactions:
      • Skin rash, itching, or hives
      • Shortness of breath, wheezing, or bronchospasm
      • Severe anaphylaxis in rare cases

      If any severe side effects occur, such as difficulty breathing or a sudden change in heart rate, seek medical attention immediately.

      Contraindications of LIDOCATON 2% 1:80000

      LIDOCATON 2% 1:80000 is contraindicated in several situations to avoid adverse effects. These include:

      • Hypersensitivity: Patients with known allergies to lidocaine or epinephrine should avoid this product.
      • Severe Heart Conditions: Patients with second or third-degree heart block or those with untreated arrhythmias should not use this medication without prior medical consultation.
      • Severe Hypertension: Due to the vasoconstrictive effects of adrenaline, it is contraindicated in patients with uncontrolled high blood pressure.
      • Pregnancy: Use in pregnant women should be limited to situations where the benefits outweigh the potential risks, especially in the first trimester.

      Storage of LIDOCATON 2% 1:80000

      Proper storage is critical to maintaining the stability and effectiveness of LIDOCATON 2% 1:80000.

      • Temperature: Store at room temperature, between 15°C and 30°C (59°F to 86°F). Do not freeze.
      • Light Protection: Keep the solution in its original packaging to protect it from light exposure, which may degrade the product.

      • LIDOCATON 2% 1:80000 is contraindicated in several situations to avoid adverse effects. These include:

        • Hypersensitivity: Patients with known allergies to lidocaine or epinephrine should avoid this product.
        • Severe Heart Conditions: Patients with second or third-degree heart block or those with untreated arrhythmias should not use this medication without prior medical consultation.
        • Severe Hypertension: Due to the vasoconstrictive effects of adrenaline, it is contraindicated in patients with uncontrolled high blood pressure.
        • Pregnancy: Use in pregnant women should be limited to situations where the benefits outweigh the potential risks, especially in the first trimester.

        Storage of LIDOCATON 2% 1:80000

        Proper storage is critical to maintaining the stability and effectiveness of LIDOCATON 2% 1:80000.

        • Temperature: Store at room temperature, between 15°C and 30°C (59°F to 86°F). Do not freeze.
        • Light Protection: Keep the solution in its original packaging to protect it from light exposure, which may degrade the product.