What is ACTOVEGIN 200mg/5ml
ACTOVEGIN 200mg/5ml is a medicinal injection formulated as a sterile solution, containing a deproteinised hemoderivative of calf blood. It is primarily used to enhance tissue oxygenation and improve metabolic processes in various medical conditions where blood supply and cellular energy metabolism are compromised. The active substance is obtained through a controlled process that removes proteins and other immunogenic components from calf blood, leaving behind biologically active low-molecular compounds.
This preparation is utilized in clinical settings for a broad range of indications, such as peripheral arterial disease, diabetic neuropathy, cognitive disorders related to cerebral insufficiency, wound healing delays, and certain eye disorders involving impaired microcirculation. By improving cellular energy metabolism and oxygen utilization, ACTOVEGIN supports tissue repair and regeneration.
- Pharmaceutical form: injection/solution, typically supplied in 5ml ampoules.
- Contains deproteinised hemoderivative of calf blood as the active ingredient.
- Used to treat conditions involving impaired oxygen supply and metabolic dysfunction.
- Acts as a metabolic enhancer to stimulate cellular repair and energy production.
How to use ACTOVEGIN 200mg/5ml
ACTOVEGIN injection is administered by healthcare professionals, either intravenously or intramuscularly, depending on the indication and severity of the condition. The method of administration and dosage must strictly follow medical advice to ensure safety and efficacy.
- Administration route: Intravenous (slow infusion) or intramuscular injection, as prescribed by the physician.
- Preparation: The solution should be inspected visually before use; only clear and colorless solutions without particles should be administered.
- Frequency: Typically given once or twice daily, depending on the clinical condition.
- Duration of treatment: Varies according to the diagnosis, commonly ranging from a few days to several weeks.
- Important considerations: Use aseptic techniques to avoid contamination. Do not mix with other drugs in the same syringe unless compatibility is confirmed.
Patients should inform their healthcare provider about any allergies, existing conditions, or other medications before starting ACTOVEGIN. Dose adjustments may be necessary based on individual response and tolerability.
Mode of Action ACTOVEGIN 200mg/5ml
ACTOVEGIN acts by enhancing oxygen and glucose uptake and utilization at the cellular level, thereby improving energy metabolism and promoting tissue repair. The deproteinised calf blood extract contains biologically active substances such as low molecular weight peptides, amino acids, nucleotides, and electrolytes that facilitate these effects.
- Improved oxygen diffusion: ACTOVEGIN increases oxygen absorption in hypoxic tissues, which supports cellular respiration and energy production.
- Enhanced glucose uptake: It stimulates glucose transport into cells, promoting aerobic metabolism.
- Support of cellular metabolism: By supplying essential substrates, it facilitates ATP production critical for cell function and regeneration.
- Neuroprotective effects: It may protect neurons from ischemic damage by improving microcirculation and metabolic activity.
- Wound healing promotion: Enhances fibroblast activity and angiogenesis, accelerating tissue repair processes.
This multimodal mechanism results in better oxygen and nutrient delivery to tissues, reduced oxidative stress, and stimulation of reparative cellular functions, especially in ischemic or metabolically compromised areas.
ACTOVEGIN 200mg/5ml Interactions ACTOVEGIN 200mg/5ml
ACTOVEGIN is generally well tolerated and exhibits a low potential for pharmacological interactions, given its unique biological origin and mode of action. However, caution is advised when used concomitantly with certain medications.
- Anticoagulants and antiplatelet agents: Although ACTOVEGIN does not directly affect coagulation, careful monitoring is recommended because improved microcirculation may theoretically influence bleeding risk.
- Hypoglycemic agents: ACTOVEGIN enhances glucose utilization, which might potentiate the effects of insulin or oral hypoglycemics, requiring blood glucose monitoring.
- Drugs affecting microcirculation: Combination with vasodilators or other circulation-improving agents should be managed carefully to avoid hypotension or excessive vasodilation.
- Immunosuppressants or biological agents: Since ACTOVEGIN is derived from animal blood, immunologic responses are rare but possible; close observation is needed if combined.
- Other injections or infusions: Compatibility with other parenteral drugs must be confirmed before co-administration.
It is essential to inform the healthcare provider of all medications being taken to avoid any unforeseen interactions and ensure safe therapy.
Dosage of ACTOVEGIN 200mg/5ml
The dosage of ACTOVEGIN injection depends on the condition being treated, patient’s age, general health, and response to therapy. It should always be prescribed and adjusted by a qualified healthcare professional.
- Standard adult dose: 1 to 2 ampoules (200mg to 400mg) daily administered via intravenous infusion or intramuscular injection.
- Intravenous infusion: Slow infusion over 30 to 60 minutes diluted in an appropriate volume of isotonic solution.
- Intramuscular injection: Given deep into muscle tissue, typically once daily.
- Duration: Usually 10 to 20 days, depending on clinical response and condition.
- Adjustments: In elderly patients or those with comorbidities, dose and frequency may be reduced to minimize adverse effects.
- Pediatric use: Limited data; use only if specifically recommended by a pediatric specialist.
Regular assessment of therapeutic efficacy and tolerability is necessary to determine whether treatment should continue or be modified.
Possible side effects of ACTOVEGIN 200mg/5ml
ACTOVEGIN is generally well tolerated, but like any medicinal product, it may cause side effects in some individuals. Awareness of potential adverse reactions helps in early identification and management.
- Local reactions: Pain, redness, or swelling at the injection site may occur.
- Allergic reactions: Rarely, hypersensitivity such as rash, itching, or anaphylaxis may develop due to its biological origin.
- Systemic effects: Headache, dizziness, or mild gastrointestinal discomfort have been reported occasionally.
- Immune responses: Though proteins are removed, there is a minimal risk of immune sensitization.
- Rare side effects: Fever, chills, or malaise indicating possible infection or systemic reaction.
If any severe or unusual symptoms develop, the patient should seek medical attention immediately. Monitoring during therapy is essential to promptly address side effects.
ACTOVEGIN 200mg/5ml Contraindications ACTOVEGIN 200mg/5ml
ACTOVEGIN should not be used in certain situations where its administration could be harmful or ineffective.
- Hypersensitivity: Known allergy to ACTOVEGIN or any of its components.
- Active infections: Use cautiously in patients with systemic infections, as metabolic stimulation may exacerbate the condition.
- Severe renal or hepatic impairment: Insufficient data on safety; use only if benefits outweigh risks.
- Pregnancy and breastfeeding: Safety not well established; use only when clearly necessary and under medical supervision.
- Children: Limited safety data; avoid unless prescribed by a specialist.
Always inform your healthcare provider of your full medical history to prevent contraindicated use.
Storage of ACTOVEGIN 200mg/5ml
Proper storage of ACTOVEGIN injection ensures its stability, potency, and safety for use.
- Temperature: Store at 2°C to 8°C (refrigerated). Avoid freezing the ampoules.
- Light protection: Keep the ampoules in their original packaging to protect from light exposure.
- Handling: Use aseptic technique when opening ampoules to avoid contamination.
- Expiration: Do not use beyond the expiry date printed on the packaging.
- Disposal: Dispose of unused or expired medicine according to local regulations to prevent environmental contamination.
Following storage instructions preserves the medication's effectiveness and reduces the risk of adverse reactions caused by degradation products.
ACTOVEGIN 200mg/5ml features an exceptional active ingredient renowned for its potent effects, comprising Deproteinised hemoderivative of Calf blood. This powerful formulation provides a superior solution for addressing diverse health concerns. With 40mg/ml concentration and an easily manageable Injection/Solution for, it remains a preferred option for countless individuals seeking effective treatment.
Introduction
All you need to know about ACTOVEGIN 200mg/5ml .
Welcome to Dwaey, specifically on ACTOVEGIN 200mg/5ml page.
This medicine contains an important and useful components, as it consists of Deproteinised hemoderivative of Calf blood.
ACTOVEGIN 200mg/5ml is available in the market in concentration 40mg/ml and in the form of Injection/Solution for.
NYCOMED AUSTRIA GmbH is the producer of ACTOVEGIN 200mg/5ml and it is imported from AUSTRIA,
The most popular alternatives of ACTOVEGIN 200mg/5ml are listed downward .
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Active Substance
Deproteinised hemoderivative of Calf blood
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Indications
- No indications available.
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Type
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Company
Frequently Asked Questions
ACTOVEGIN 200mg/5ml should be stored according to the instructions provided by NYCOMED AUSTRIA GmbH.
In general, it is recommended to store ACTOVEGIN 200mg/5ml in a cool, dry place, away from direct sunlight
and out of the reach of children.
The duration of treatment with ACTOVEGIN 200mg/5ml may vary depending on the condition being treated
and the guidance of your healthcare provider. It is important to follow the prescribed treatment
plan and continue taking ACTOVEGIN 200mg/5ml for the recommended duration, even if your symptoms improve.
If you have any concerns or questions about the duration of treatment, consult your healthcare provider.
It is important to check with your healthcare provider or read the medication label for specific
instructions regarding alcohol consumption while taking ACTOVEGIN 200mg/5ml. Some medications, including
ACTOVEGIN 200mg/5ml, may have interactions with alcohol that can reduce effectiveness, increase side
effects, or pose other risks to your health. It is best to follow the guidance provided by your
healthcare professional.
If you miss a dose of ACTOVEGIN 200mg/5ml, take it as soon as you remember. However, if it is close
to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing
schedule. Do not take a double dose to make up for a missed one unless advised by your healthcare provider.
No, do not stop taking ACTOVEGIN 200mg/5ml without consulting your healthcare provider, even if your
symptoms improve. It is important to complete the full course of treatment as prescribed. Stopping
the medication prematurely may lead to a relapse or incomplete resolution of the condition. If you
have concerns about the duration of treatment, consult your healthcare provider for guidance.
It is important to consult your healthcare provider before taking ACTOVEGIN 200mg/5ml if you are
pregnant or breastfeeding. They will be able to assess the potential risks and benefits based on your
specific situation. Please note that the safety and suitability of ACTOVEGIN 200mg/5ml during pregnancy
or breastfeeding may depend on the active substance [Active Substance], concentration 40mg/ml,
and the specific recommendations of NYCOMED AUSTRIA GmbH.
The effects of ACTOVEGIN 200mg/5ml on your ability to drive or operate machinery can vary depending on
the active substance [Active Substance], concentration 40mg/ml, and individual factors.
Some medications may cause drowsiness, dizziness, or other side effects that can impair your judgment
or coordination. It is important to read the medication label or consult your healthcare provider to
understand any potential effects on your ability to perform tasks that require alertness.
The instructions for taking ACTOVEGIN 200mg/5ml with or without food may vary depending on the medication
and the recommendations of NYCOMED AUSTRIA GmbH. Some medications may be more effective when taken with
food to enhance absorption or reduce stomach irritation, while others may need to be taken on an empty
stomach for optimal absorption. Read the medication label or consult your healthcare provider for specific instructions.
The use of ACTOVEGIN 200mg/5ml in children or elderly individuals may depend on various factors, including
the specific medication, type Injection/Solution for, and the recommendations of NYCOMED AUSTRIA GmbH. Some
medications may have specific dosing instructions or precautions for these age groups. Consult your
healthcare provider or read the medication label for information regarding the safe and appropriate use
of ACTOVEGIN 200mg/5ml in children or elderly individuals.
Dwaey
All medical information published on the Dwaey website aims to increase medical awareness and health education among users. However, it is not a substitute for professional medical advice. Always consult with a specialist doctor. We strongly advise against using any information or medicine found on the site without referring to your healthcare provider.
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