ACHROMYCIN V 250mg Capsules (Hard Gelatin)

What is ACHROMYCIN V 250mg

ACHROMYCIN V 250mg is a hard gelatin capsule formulation that contains Tetracycline, a broad-spectrum antibiotic used to treat various bacterial infections. Tetracycline belongs to the class of antibiotics known as tetracyclines, which work by inhibiting bacterial protein synthesis, thereby preventing the growth and spread of bacteria.

• Commonly used to treat respiratory tract infections, skin infections (like acne), urinary tract infections, and certain sexually transmitted infections.
• Effective against both gram-positive and gram-negative bacteria.
• Often prescribed when penicillin is not suitable or when the causative bacteria are resistant to other antibiotics.
• Not effective against viral infections (e.g., common cold or flu).

This medication is typically taken orally and is available in 250mg strength per capsule.

How to use ACHROMYCIN V 250mg

To ensure optimal effectiveness and safety, ACHROMYCIN V should be used exactly as prescribed by your physician.

• Take the capsule on an empty stomach, at least 1 hour before or 2 hours after meals.
• Swallow with a full glass of water to reduce the risk of esophageal irritation or ulcers.
• Do not lie down immediately after taking the medication — wait at least 30 minutes.
• Complete the full course of therapy even if symptoms improve earlier to prevent resistance.
• Avoid taking dairy products, antacids, calcium, magnesium, or iron supplements within 2 hours of taking the capsule, as they may impair absorption.

Always follow the exact dosing schedule and duration as advised by your healthcare provider.

Mode of Action ACHROMYCIN V 250mg

Tetracycline works by targeting bacterial protein synthesis, which is essential for bacterial growth and survival.

• Binds reversibly to the 30S ribosomal subunit of bacteria.
• Prevents the attachment of aminoacyl-tRNA to the ribosomal acceptor site, halting protein synthesis.
• Bacteriostatic in action — it stops bacteria from multiplying but does not directly kill them.
• Effective against a wide range of organisms, including atypical bacteria like Mycoplasma and Chlamydia.

This mechanism allows ACHROMYCIN V to treat infections that are resistant to other antibiotics and makes it suitable for polymicrobial infections.

ACHROMYCIN V 250mg Interactions ACHROMYCIN V 250mg

Tetracycline can interact with various substances and medications, which may affect its efficacy or increase the risk of side effects.

• Antacids, calcium, iron, magnesium, and zinc supplements – reduce absorption of the drug.
• Oral contraceptives – may decrease the effectiveness of birth control pills.
• Warfarin – increased anticoagulant effects may occur; monitor INR closely.
• Penicillin – concurrent use may reduce the effectiveness of penicillin antibiotics.
• Retinoids (e.g., isotretinoin) – coadministration may increase the risk of intracranial hypertension.

Inform your healthcare provider about all the medications and supplements you are taking to avoid harmful interactions.

Dosage of ACHROMYCIN V 250mg

The dosage of ACHROMYCIN V depends on the type and severity of infection, as well as the patient's age and renal function.

• Adults: Usual dose is 250mg to 500mg every 6 to 12 hours.
• Children over 8 years: Dosing is typically based on weight (e.g., 25–50 mg/kg/day divided every 6–12 hours).
• Renal impairment: Dose adjustment may be required.

Always follow the prescribed regimen and avoid skipping or doubling doses.

Possible side effects of ACHROMYCIN V 250mg

While generally well tolerated, ACHROMYCIN V can cause side effects in some individuals.

• Common side effects:
  • Nausea or vomiting
  • Diarrhea
  • Loss of appetite
  • Photosensitivity (increased risk of sunburn)
• Less common but serious:
  • Allergic reactions (rash, swelling, difficulty breathing)
  • Pseudomembranous colitis
  • Liver toxicity or hepatitis
  • Esophagitis or esophageal ulceration

Report any unusual or severe symptoms to your healthcare provider immediately.

ACHROMYCIN V 250mg Contraindications ACHROMYCIN V 250mg

ACHROMYCIN V should not be used in certain populations due to safety concerns.

• Hypersensitivity: Known allergy to tetracycline antibiotics.
• Pregnancy: Contraindicated in the second and third trimesters due to risk of fetal bone and tooth discoloration.
• Children under 8 years: Not recommended as it may cause permanent teeth discoloration and affect bone development.
• Severe liver dysfunction: Use with caution or avoid due to hepatic metabolism.

Consult a healthcare provider before initiating therapy to ensure safety and suitability.

Storage of ACHROMYCIN V 250mg

Proper storage of the medication ensures its effectiveness and stability.

• Store in a cool, dry place below 25°C (77°F).
• Keep capsules in their original blister packaging to protect from moisture and light.
• Do not use after the expiration date printed on the pack.
• Keep out of reach of children and pets.
• Do not store in bathrooms or near sinks where it may get exposed to humidity.

If you notice any changes in color or integrity of the capsules, discard them and consult your pharmacist.