HUMULIN-R (REGULAR) 100 Units/ml Injection

What is HUMULIN-R (REGULAR) 100 Units/ml

HUMULIN-R (REGULAR) 100 Units/ml is a type of insulin that is used to manage blood glucose levels in people with diabetes. It is a synthetic version of human insulin, designed to mimic the body’s natural insulin response. This insulin is classified as short-acting or regular insulin, which means it starts working relatively quickly to control blood sugar after meals.

• Formulation: Available as a 10 ml vial with 100 Units/ml of insulin.
• Primary Use: It is used to control blood glucose levels in both Type 1 and Type 2 diabetes, primarily after meals.
• Onset: Begins to work approximately 30 minutes after injection.
• Peak Action: Reaches its maximum effect within 2 to 3 hours.
• Duration: Effects last for about 5-8 hours, making it effective for post-meal glucose control.
• Administration: Injected subcutaneously (under the skin), typically 30 minutes before meals.

HUMULIN-R is essential for individuals who need rapid insulin action to control blood glucose levels, especially for those with fluctuating post-meal blood sugar levels.

How to use HUMULIN-R (REGULAR) 100 Units/ml

Proper administration of HUMULIN-R (REGULAR) 100 Units/ml is crucial for maintaining good blood sugar control and minimizing risks associated with improper dosing. Here’s how to use it correctly:

• Preparation:
  • Ensure your hands are clean before handling insulin or syringes.
  • Check the insulin vial for any discoloration or particles; it should be clear and colorless.
• Dosage:
  • Your healthcare provider will determine the appropriate starting dose. Typically, the dose is based on your body weight, blood glucose levels, and carbohydrate intake.
  • Use a sterile syringe or insulin pen to draw the prescribed dose. Inject 30 minutes before meals for optimal results.
• Injection:
  • Inject the insulin subcutaneously (under the skin) into areas such as the abdomen, thigh, or upper arm.
  • Rotate injection sites to reduce the risk of developing lumps or scars under the skin.
• Post-Injection Care:
  • Always dispose of used syringes and needles in a designated sharps container.
  • Check your blood glucose levels regularly to assess the effectiveness of your insulin therapy.

Proper timing and technique are vital to ensure you get the best results from your treatment with HUMULIN-R.

Mode of Action HUMULIN-R (REGULAR) 100 Units/ml

HUMULIN-R (REGULAR) 100 Units/ml works by mimicking the natural action of insulin, a hormone produced by the pancreas that is essential for regulating blood glucose levels. Here’s how it works:

• Insulin Receptor Binding: HUMULIN-R binds to insulin receptors on the surface of muscle, fat, and liver cells, triggering the movement of glucose into these cells.
• Glucose Uptake: Once bound to its receptor, insulin facilitates the entry of glucose into cells, where it can be used for energy or stored for later use.
• Rapid Action: HUMULIN-R starts to lower blood glucose levels within 30 minutes of administration, which helps prevent blood sugar spikes after meals.
• Peak Effect: The insulin reaches its peak effectiveness in about 2 to 3 hours after injection, providing optimal postprandial glucose control.
• Duration: Its effects last for 5-8 hours, making it ideal for short-term glucose management following meals.

In essence, HUMULIN-R functions to lower blood sugar by enhancing glucose uptake into cells, mimicking the insulin your body would naturally produce in response to food intake.

HUMULIN-R (REGULAR) 100 Units/ml Interactions HUMULIN-R (REGULAR) 100 Units/ml

Many medications can interact with HUMULIN-R (REGULAR) 100 Units/ml, either increasing or decreasing its effectiveness. It is crucial to be aware of these interactions and work closely with your healthcare provider to avoid complications:

• Oral Antidiabetic Medications:
  • Drugs such as metformin and sulfonylureas enhance the blood-glucose-lowering effects of HUMULIN-R, but they may also increase the risk of hypoglycemia.
• Beta-Blockers:
  • Medications like propranolol can mask symptoms of hypoglycemia (e.g., shaking, sweating, rapid heartbeat), making it difficult to detect low blood sugar.
• Corticosteroids:
  • Corticosteroids, such as prednisone, can raise blood glucose levels, often requiring higher doses of insulin to maintain control.
• Diuretics:
  • Medications like thiazide diuretics can elevate blood glucose, potentially necessitating adjustments in insulin therapy.
• Alcohol:
  • Alcohol consumption may cause unpredictable blood sugar fluctuations, either lowering or raising blood glucose levels. Always monitor your blood sugar when drinking alcohol.

Always inform your doctor of all medications you are taking to prevent any potential interactions that may interfere with your blood glucose control.

Dosage of HUMULIN-R (REGULAR) 100 Units/ml

The dosage of HUMULIN-R (REGULAR) 100 Units/ml is highly individualized. Your healthcare provider will determine the appropriate dosage based on several factors, including your blood glucose levels, activity level, and other medications you may be taking. Here’s an overview:

• Initial Dose:
  • The typical starting dose is 0.5 to 1 unit per kilogram of body weight per day, but this may be adjusted according to your response.
• Meal-time Dosing:
  • HUMULIN-R is usually injected 30 minutes before meals to control blood sugar spikes after eating. Doses may vary depending on the carbohydrate content of your meal.
• Adjustment of Dose:
  • Dosages are adjusted based on blood glucose monitoring results. Factors like exercise, illness, and stress can also influence insulin needs.
• Combination with Other Insulins:
  • HUMULIN-R is often used in combination with longer-acting insulins or other medications for comprehensive glucose control.

Regular blood glucose monitoring is key to adjusting your insulin doses and ensuring you stay within your target range for optimal control.

Possible side effects of HUMULIN-R (REGULAR) 100 Units/ml

As with all medications, HUMULIN-R (REGULAR) 100 Units/ml can cause side effects. Some of these may be mild, while others may require medical attention. Here’s a breakdown of potential side effects:

• Common Side Effects:
  • Hypoglycemia (Low Blood Sugar): The most common side effect of insulin therapy. Symptoms include shaking, sweating, dizziness, and confusion.
  • Injection Site Reactions: Redness, swelling, or pain at the injection site can occur.
• Less Common Side Effects:
  • Weight Gain: Insulin therapy can cause weight gain in some individuals.
  • Allergic Reactions: Rare but serious reactions include rash, itching, and swelling. Seek medical attention immediately if any severe allergic reactions occur.
• Severe Side Effects:
  • Severe Hypoglycemia: If untreated, low blood sugar can lead to seizures, loss of consciousness, or even death.
  • Insulin Overdose: Overdosing on insulin can lead to dangerous drops in blood sugar levels.

Contact your healthcare provider if you experience any unusual or severe side effects, or if you have any concerns about the use of HUMULIN-R.

HUMULIN-R (REGULAR) 100 Units/ml Contraindications HUMULIN-R (REGULAR) 100 Units/ml

HUMULIN-R (REGULAR) 100 Units/ml is a medication that can be highly effective for managing diabetes, but it is not suitable for everyone. Certain conditions or factors can increase the risk of complications when using this insulin. Below are the primary contraindications for this drug:

• Hypersensitivity to Insulin: People who are allergic or have shown hypersensitivity to insulin, including human insulin or any of the ingredients in HUMULIN-R, should not use this medication.
• Hypoglycemia: Insulin is not recommended for patients who are experiencing or have a history of severe low blood sugar (hypoglycemia). This can lead to life-threatening complications if not managed properly.
• Severe Renal or Hepatic Impairment: Individuals with significant kidney or liver dysfunction may experience prolonged effects of insulin, requiring careful monitoring and dose adjustments.
• Severe Insulin Resistance: Patients with severe insulin resistance may not achieve effective glucose control with HUMULIN-R alone and may require additional medications or different insulin types.
• Pregnancy and Breastfeeding: While HUMULIN-R can be used during pregnancy, it requires careful monitoring and dose adjustments to ensure proper glucose control. The use of insulin during breastfeeding should be done under the supervision of a healthcare provider.
• Acute Illness: Patients with severe infections, fever, trauma, or surgery should consult their healthcare provider before starting or adjusting insulin therapy, as these conditions can alter insulin requirements.

Always consult your healthcare provider to determine whether HUMULIN-R is appropriate for your specific medical condition. Adjustments may be needed based on your health history and current status.

Storage of HUMULIN-R (REGULAR) 100 Units/ml

Proper storage of HUMULIN-R (REGULAR) 100 Units/ml is crucial to ensure that the insulin remains effective throughout its use. Incorrect storage can compromise its potency and safety. Here’s how you should store this medication:

• Unopened Vials:
  • Store unopened vials in the refrigerator between 2°C to 8°C (36°F to 46°F).
  • Do not freeze. Freezing will damage the insulin and make it ineffective.
  • Keep the vial in its original carton to protect it from light.
• Opened Vials:
  • After opening, HUMULIN-R can be kept at room temperature (below 30°C or 86°F) for up to 28 days.
  • Once the vial is opened, avoid exposure to direct heat or sunlight.
  • If not in use, always recap the vial and store it in a cool place away from sunlight.
• Disposal:
  • Once the insulin vial or pen is empty, dispose of it according to local regulations, typically in a sharps container.
• General Guidelines:
  • Do not use insulin if it appears discolored, cloudy, or has particles floating in it after opening.
  • If in doubt about the insulin’s appearance, consult your pharmacist or healthcare provider.

Correct storage ensures that your insulin maintains its efficacy and safety, minimizing the risk of treatment failure and complications.