(BAXTER) Glucose 5% w/v and Potassium Chloride 0.15 % w/v Infusion/Solution for

What is (BAXTER) Glucose 5% w/v and Potassium Chloride 0.15 % w/v

(BAXTER) Glucose 5% w/v and Potassium Chloride 0.15% w/v is a sterile, non-pyrogenic intravenous infusion used primarily for fluid replacement, electrolyte replenishment, and energy supply in patients. It combines two essential components:

• Glucose (5% w/v): A simple sugar that provides immediate energy to the body and prevents protein catabolism during fluid therapy.
• Potassium Chloride (0.15% w/v): A source of potassium, essential for maintaining normal nerve and muscle function, especially cardiac activity.

This solution is commonly indicated in cases of mild to moderate hypokalemia, dehydration, and as part of parenteral nutrition regimens. It is especially useful in clinical scenarios where both glucose and potassium supplementation are needed simultaneously.

How to use (BAXTER) Glucose 5% w/v and Potassium Chloride 0.15 % w/v

How to Use (BAXTER) Glucose 5% w/v and Potassium Chloride 0.15% w/v

This infusion should only be administered by healthcare professionals in a controlled clinical environment. It is delivered intravenously, typically through a peripheral or central vein.

• Inspect the solution and bag for clarity, particulate matter, or leaks before administration. Discard if compromised.
• Administer using a sterile IV set, maintaining aseptic conditions at all times.
• The infusion rate and volume depend on the patient's clinical condition, fluid requirements, electrolyte levels, and overall treatment goals.
• Monitor electrolytes (especially potassium) and blood glucose during therapy to avoid hyperkalemia or hyperglycemia.
• Use an infusion pump for precise rate control, especially in patients with cardiovascular, renal, or diabetic conditions.

Avoid simultaneous infusion with blood products or incompatible drugs unless deemed safe by a clinician.

Mode of Action (BAXTER) Glucose 5% w/v and Potassium Chloride 0.15 % w/v

Mode of Action of (BAXTER) Glucose 5% w/v and Potassium Chloride 0.15% w/v

This IV solution combines the pharmacodynamic effects of glucose and potassium chloride:

• Glucose: Upon infusion, glucose is metabolized through glycolysis to produce energy in the form of ATP. It helps spare proteins and provides immediate caloric support during periods of fasting or metabolic stress.
• Potassium Chloride: Potassium ions are vital for cellular membrane potential, nerve impulse conduction, and muscle function. Chloride helps maintain acid-base balance and osmotic stability.

Together, the solution replenishes energy and electrolytes, restores fluid balance, and prevents or treats hypokalemia, which can otherwise result in serious cardiac and neuromuscular disturbances.

(BAXTER) Glucose 5% w/v and Potassium Chloride 0.15 % w/v Interactions (BAXTER) Glucose 5% w/v and Potassium Chloride 0.15 % w/v

(BAXTER) Glucose 5% w/v and Potassium Chloride 0.15% w/v Interactions

This IV solution may interact with several classes of medications. Caution is advised when co-administered with:

• Potassium-sparing diuretics (e.g., spironolactone, amiloride): May increase the risk of hyperkalemia.
• ACE inhibitors and ARBs: Enhance potassium retention, raising the risk of cardiac arrhythmias due to elevated serum potassium.
• NSAIDs: May impair renal potassium excretion, enhancing hyperkalemia risk.
• Insulin: Facilitates cellular uptake of potassium and glucose; dosage adjustments may be necessary.
• Cardiac glycosides (e.g., digoxin): Hypokalemia increases digoxin toxicity risk; correction with this infusion may reduce toxicity but must be carefully monitored.

Always evaluate drug profiles and monitor serum electrolytes and glucose to avoid adverse outcomes.

Dosage of (BAXTER) Glucose 5% w/v and Potassium Chloride 0.15 % w/v

Dosage of (BAXTER) Glucose 5% w/v and Potassium Chloride 0.15% w/v

The dosage is individualized based on clinical condition, age, weight, renal function, and electrolyte balance. General guidance includes:

• Adults: 500 ml to 3000 ml per day depending on hydration and potassium needs.
• Potassium limit: Should not exceed 10–20 mEq/hour for peripheral infusion or 40 mEq/hour for central infusion under ECG monitoring.
• Infusion rate: Typically 100–125 ml/hour, but may be increased in emergency situations under supervision.

Continuous monitoring of serum potassium, renal function, and glucose levels is essential during administration.

Possible side effects of (BAXTER) Glucose 5% w/v and Potassium Chloride 0.15 % w/v

Possible Side Effects of (BAXTER) Glucose 5% w/v and Potassium Chloride 0.15% w/v

While generally well tolerated when used correctly, potential side effects include:

• Hyperkalemia: May present with muscle weakness, paresthesia, or cardiac arrhythmias.
• Hyperglycemia: Particularly in diabetic patients or with high-volume infusion.
• Phlebitis: Inflammation at the injection site, especially with peripheral administration.
• Fluid overload: May lead to pulmonary edema or congestive heart failure in at-risk populations.
• Electrolyte imbalances: If not monitored, overcorrection can lead to hypo- or hyperkalemia.

Patients must be monitored closely to detect and manage side effects early.

(BAXTER) Glucose 5% w/v and Potassium Chloride 0.15 % w/v Contraindications (BAXTER) Glucose 5% w/v and Potassium Chloride 0.15 % w/v

Contraindications of (BAXTER) Glucose 5% w/v and Potassium Chloride 0.15% w/v

This product should not be used in the following cases:

• Hyperkalemia: Existing elevated serum potassium levels pose a serious cardiac risk.
• Severe renal impairment: May lead to impaired potassium excretion and electrolyte imbalance.
• Uncontrolled diabetes mellitus: Risk of severe hyperglycemia and osmotic diuresis.
• Addison’s disease: Due to impaired aldosterone secretion and potassium handling.
• Severe dehydration with sodium depletion: Requires sodium replacement first.

Always evaluate renal, endocrine, and cardiac function before initiating therapy.

Storage of (BAXTER) Glucose 5% w/v and Potassium Chloride 0.15 % w/v

Storage of (BAXTER) Glucose 5% w/v and Potassium Chloride 0.15% w/v

To maintain efficacy and sterility, proper storage is crucial:

• Store at controlled room temperature: 15–25°C (59–77°F).
• Protect from freezing and direct sunlight.
• Keep in original outer carton to protect from light.
• Do not use if the solution is discolored or contains visible particles.
• Check for leaks or compromised packaging before use.

Do not store partially used bags. Discard any unused portion after opening.