CITAPRAM 40mg Tablets/Film-coated

What is CITAPRAM 40mg

CITAPRAM 40mg is a prescription medication that contains the active ingredient Citalopram Hydrobromide, a selective serotonin reuptake inhibitor (SSRI) commonly used to treat major depressive disorder (MDD) and generalized anxiety disorder (GAD). It works by increasing the levels of serotonin, a chemical in the brain that affects mood, emotion, and sleep.

• Classification: Antidepressant (SSRI)
• Form: Film-coated tablets
• Strength: 40mg
• Pack size: 30 tablets (10s blister x 3)
• Generic Name: Citalopram Hydrobromide

It is often prescribed as part of a treatment plan for depression and related mood disorders, and may take several weeks to show full therapeutic effect.

How to use CITAPRAM 40mg

CITAPRAM 40mg should be used exactly as prescribed by your healthcare provider. It is usually taken once daily, with or without food.

• Administration: Swallow the tablet whole with a glass of water. Do not crush, chew, or break it.
• Timing: Preferably take it at the same time each day, usually in the morning or evening.
• Missed Dose: If you miss a dose, take it as soon as you remember unless it is close to the time of your next dose. Do not double the dose to catch up.
• Duration: Continue using the medication even if you feel well. Do not stop abruptly without consulting your doctor.
• Adjustment: Your doctor may adjust your dose based on your response and tolerability.

It is essential to follow the prescribed course of treatment and to attend follow-up appointments to monitor progress and any side effects.

Mode of Action CITAPRAM 40mg

CITAPRAM works by selectively inhibiting the reuptake of serotonin (5-HT) in the brain, which leads to an increase in serotonin levels in the synaptic cleft. This helps improve communication between neurons and has a positive effect on mood and emotional state.

• Primary Mechanism: Selective serotonin reuptake inhibition (SSRI)
• Result: Increased extracellular levels of serotonin in the brain
• Clinical Effect: Improves symptoms of depression and anxiety by stabilizing mood
• Onset of Action: May take 1–4 weeks to observe noticeable improvements

By enhancing serotonin transmission, CITAPRAM helps regulate mood, reduce anxiety, and improve overall emotional balance in individuals with mood disorders.

CITAPRAM 40mg Interactions CITAPRAM 40mg

CITAPRAM may interact with various medications, increasing the risk of side effects or reducing therapeutic efficacy.

• MAO Inhibitors: Combining with monoamine oxidase inhibitors (e.g., phenelzine, tranylcypromine) can cause serious, potentially fatal interactions. Allow at least 14 days between stopping MAOIs and starting CITAPRAM.
• Other SSRIs or SNRIs: Increases risk of serotonin syndrome
• NSAIDs & Aspirin: May increase the risk of bleeding
• Anticoagulants: Such as warfarin – monitor INR levels closely
• Triptans: (e.g., sumatriptan) – Risk of serotonin syndrome when used together
• Alcohol: Can increase side effects such as dizziness and drowsiness
• Enzyme Inhibitors: CYP2C19 inhibitors (like omeprazole) may raise blood levels of CITAPRAM

Always inform your doctor about all medications, supplements, or herbal products you are using before starting CITAPRAM.

Dosage of CITAPRAM 40mg

The dosage of CITAPRAM 40mg should be determined by a healthcare professional based on individual patient factors.

• Usual Adult Dose: 20mg once daily, which may be increased to a maximum of 40mg/day
• Geriatric Patients: Lower starting dose (often 20mg/day) recommended due to increased sensitivity
• Hepatic Impairment: Dosage adjustments required; maximum 20mg/day
• Pediatric Use: Not typically recommended; safety and efficacy not established

Do not exceed 40mg/day due to the risk of QT interval prolongation. Regular ECG monitoring may be advised in patients with heart conditions.

Possible side effects of CITAPRAM 40mg

Like all medications, CITAPRAM may cause side effects, although not everyone experiences them. Most are mild and temporary, but some may require medical attention.

• Common Side Effects:
  • Nausea
  • Dry mouth
  • Drowsiness or fatigue
  • Increased sweating
  • Sexual dysfunction
• Serious Side Effects:
  • Serotonin syndrome (confusion, agitation, fever)
  • QT prolongation (irregular heartbeat)
  • Seizures
  • Severe allergic reactions

Seek immediate medical help if you notice symptoms such as chest pain, shortness of breath, sudden mood changes, or suicidal thoughts.

CITAPRAM 40mg Contraindications CITAPRAM 40mg

CITAPRAM is not suitable for everyone. There are certain conditions and situations in which this medicine should not be used.

• Allergy: Known hypersensitivity to citalopram or any excipients in the formulation
• MAOI Use: Concurrent use or recent use (within 14 days) of monoamine oxidase inhibitors
• QT Prolongation: Patients with congenital long QT syndrome or known heart rhythm disorders
• Severe Liver Impairment: Use with caution and at reduced doses
• Pregnancy & Lactation: Only use if the benefits outweigh the risks; consult your doctor
• Use in children: Generally not recommended unless under specialist supervision

Always disclose your full medical history to your healthcare provider before beginning treatment with CITAPRAM.

Storage of CITAPRAM 40mg

Proper storage of medication is essential to maintain its effectiveness and safety.

• Storage Temperature: Store at room temperature (15°C to 30°C)
• Keep Away From: Moisture, direct sunlight, and heat sources
• Child Safety: Keep out of reach and sight of children
• Do Not Use: If the packaging is damaged or past the expiry date
• Disposal: Dispose of unused or expired medication properly – do not flush down the toilet

Storing CITAPRAM correctly ensures the medication remains safe and effective throughout its shelf life.