DEXIPAN 5% Cream

What is DEXIPAN 5%

DEXIPAN 5% Cream is a topical dermatological product formulated with Dexpanthenol, a derivative of pantothenic acid (vitamin B5). This cream is primarily used for enhancing the healing of skin and mucous membranes and is available in a 20g tube for easy application. Dexpanthenol converts into pantothenic acid in the skin, a vital nutrient for maintaining skin integrity, regeneration, and hydration.

• Healing agent: Promotes rapid epithelial regeneration in minor wounds, abrasions, and burns.
• Skin hydration: Acts as a humectant that binds water, keeping the skin soft and supple.
• Vitamin B5 enrichment: Supports metabolic functions in skin cells necessary for recovery and growth.
• Versatile use: Ideal for dry skin, chapped lips, nipple care during breastfeeding, diaper rash, and tattoo aftercare.

DEXIPAN 5% Cream is especially beneficial in cases of compromised skin barrier due to environmental aggressors, minor trauma, or chronic dryness. Its emollient base makes it suitable for sensitive skin, including in infants and the elderly.

How to use DEXIPAN 5%

Correct usage of DEXIPAN 5% Cream maximizes its therapeutic benefits. It is intended for external use only and should be applied to clean, dry skin.

• Cleanse the area: Gently wash the affected site with water and mild soap; pat dry.
• Apply the cream: Squeeze a small amount onto a fingertip and apply a thin, even layer over the area.
• Massage gently: Rub gently into the skin to ensure full absorption.
• Repeat: Use 2–4 times daily, or as recommended by your healthcare provider.

Do not use DEXIPAN on infected, weeping, or deep wounds without medical supervision. Avoid contact with eyes and mucous membranes. Always wash your hands before and after application unless treating your hands directly. For breastfeeding mothers using it on cracked nipples, clean the area before nursing.

Mode of Action DEXIPAN 5%

The active ingredient in DEXIPAN 5% Cream is Dexpanthenol, which penetrates the skin and converts into pantothenic acid (vitamin B5). This vitamin is crucial for forming coenzyme A (CoA), which is vital in the synthesis and metabolism of proteins and fatty acids in skin cells.

• Accelerates epithelial regeneration: Enhances cellular proliferation and differentiation, especially in keratinocytes and fibroblasts.
• Improves skin barrier: Increases lipid production in the stratum corneum, restoring the protective function of the skin.
• Hydration and elasticity: Acts as a moisturizer by drawing water into the skin and improving its flexibility.
• Anti-inflammatory effects: Soothes irritated skin and reduces redness, itchiness, and inflammation.

By supporting metabolic functions and skin regeneration, DEXIPAN 5% Cream helps treat and prevent various dermatological conditions involving dryness, irritation, or superficial damage.

DEXIPAN 5% Interactions DEXIPAN 5%

DEXIPAN 5% Cream is a topical preparation with minimal systemic absorption, which significantly limits the potential for drug interactions. However, some considerations are necessary:

• Concurrent topical medications: Do not apply other creams, ointments, or lotions simultaneously on the same area unless advised by a healthcare provider.
• Use with corticosteroids: Topical corticosteroids may counteract the regenerative and moisturizing effects of Dexpanthenol if applied concurrently.
• Skin sensitizers: Avoid using with other agents that may cause irritation, such as alcohol-based sanitizers or exfoliants.
• Medical advice: If you're undergoing treatment with prescription topical agents (e.g., antibiotics, antifungals), consult your doctor or pharmacist before combining with DEXIPAN.

No significant interactions with systemic medications have been reported. However, for patients with extensive skin application needs or pre-existing conditions, professional consultation is recommended.

Dosage of DEXIPAN 5%

The appropriate dosage of DEXIPAN 5% Cream depends on the skin condition being treated, patient age, and clinical response. In general, the following dosing guidelines apply:

• Adults: Apply a thin layer 2 to 4 times daily to the affected area or as directed by a healthcare provider.
• Children: Safe for pediatric use, including infants. Use 1 to 3 times daily for conditions like diaper rash.
• Post-tattoo care: Apply 2 to 3 times daily during the healing phase unless advised otherwise.
• Nipple care (lactating women): Apply after breastfeeding and cleanse before the next feeding if required.

There is no known risk of overdose with topical Dexpanthenol. However, frequent or heavy application can sometimes cause overhydration or maceration of the skin. Always follow prescribed dosage for best outcomes.

Possible side effects of DEXIPAN 5%

DEXIPAN 5% Cream is usually well tolerated, even on sensitive skin. Side effects are rare, but users should still be aware of potential adverse reactions.

• Common (rare occurrence): Temporary burning, stinging, or redness at the application site.
• Hypersensitivity: Some individuals may experience allergic reactions such as itching, rash, or swelling.
• Contact dermatitis: Uncommon but possible with prolonged use or in sensitive individuals.
• Systemic effects: Not reported due to minimal absorption through intact skin.

Discontinue use if signs of irritation or allergy appear and consult a healthcare provider. Always perform a patch test before applying extensively, especially in individuals with sensitive or allergy-prone skin.

DEXIPAN 5% Contraindications DEXIPAN 5%

DEXIPAN 5% Cream is contraindicated in certain specific conditions. It is essential to use the product under proper medical advice in such situations.

• Known allergy: Hypersensitivity to Dexpanthenol or any of the excipients in the formulation.
• Severe infections: Avoid applying on infected or oozing wounds unless under strict medical guidance.
• Large open wounds: Not suitable for deep or surgical wounds without healthcare supervision.

Patients with a history of allergic skin reactions to topical medications should consult a healthcare provider before using this cream. Always read the package insert and consult your pharmacist if uncertain.

Storage of DEXIPAN 5%

Proper storage ensures the safety and effectiveness of DEXIPAN 5% Cream throughout its shelf life.

• Temperature: Store below 25°C (77°F). Avoid freezing.
• Protection from light: Keep the tube out of direct sunlight and store in its original packaging.
• Seal integrity: Always close the cap tightly after use to avoid contamination or drying out.
• Out of children's reach: Store in a location inaccessible to infants or young children.

Check the expiration date before use. Do not use the product if the cream changes in color, consistency, or smell. Dispose of any expired or unused product according to local pharmaceutical disposal guidelines.