DEXANOL 5% Cream

What is DEXANOL 5%

DEXANOL 5% Cream is a topical skin preparation containing Dexpanthenol, the biologically active form of pantothenic acid (vitamin B5). Formulated as a 5% cream in a 30g collapsible tube, it is designed for direct application to the skin to promote healing and moisturization. Dexpanthenol is widely recognized for its skin-regenerative and anti-inflammatory properties, making it ideal for treating minor skin injuries, dryness, and irritation.

• Skin barrier repair: DEXANOL supports the regeneration of the epidermis and strengthens the skin’s natural barrier.
• Wound healing: It accelerates epithelialization in minor abrasions, cuts, and superficial wounds.
• Moisturizing effect: It hydrates the skin and prevents dehydration-related irritation.
• Safe for sensitive skin: It is suitable for use on delicate areas such as the face, nipples (during lactation), and perianal region.

DEXANOL 5% is commonly used to manage conditions like diaper rash, sunburn, minor burns, cracked skin, and post-tattoo care. It is also recommended for the prevention of skin breakdown in vulnerable populations such as infants and the elderly.

How to use DEXANOL 5%

Using DEXANOL 5% Cream correctly ensures optimal therapeutic benefit and minimizes the risk of side effects. It is intended for external use only.

• Step 1 – Cleanse the area: Gently wash the affected area with mild soap and water, then pat it dry.
• Step 2 – Apply the cream: Squeeze a small amount onto your fingertip and apply a thin, even layer to the affected area.
• Step 3 – Frequency: Use 1 to 3 times daily, or as directed by your physician or pharmacist.
• Step 4 – Avoid contamination: Do not let the tube opening touch your skin directly to prevent bacterial contamination.

DEXANOL is gentle enough for use on all skin types and suitable for all age groups, including infants. However, avoid applying it to deep wounds or infected skin unless advised by a healthcare professional. Avoid contact with eyes, mucous membranes, or inhalation. If you experience worsening symptoms or signs of irritation, discontinue use and consult a doctor.

Mode of Action DEXANOL 5%

DEXANOL 5% Cream exerts its effect through its active ingredient, Dexpanthenol, which is rapidly converted in the skin to pantothenic acid—a component of coenzyme A (CoA). CoA plays a central role in the cellular metabolism of fatty acids and proteins, which are essential for skin regeneration.

• Promotes epithelialization: Enhances the proliferation of fibroblasts and keratinocytes, accelerating the closure of minor wounds.
• Moisturization: Acts as a humectant, drawing water into the outer layer of the skin, thereby maintaining hydration and preventing dryness.
• Anti-inflammatory effect: Reduces skin redness, itching, and inflammation associated with irritants or dryness.
• Improves skin elasticity: Helps maintain suppleness, especially in areas prone to cracking or mechanical stress.

The overall effect of DEXANOL 5% is enhanced tissue repair, improved skin integrity, and long-term hydration—making it an essential cream for daily skin maintenance and recovery from superficial damage.

DEXANOL 5% Interactions DEXANOL 5%

Topical DEXANOL 5% Cream generally has a low risk of interactions due to its localized action. However, some precautions are necessary:

• Concurrent topical agents: Avoid using other topical creams, ointments, or corticosteroids at the same site unless directed by a healthcare professional, as they may alter skin permeability or reduce effectiveness.
• Antiseptic agents: Some antiseptics or alcohol-based products may inactivate Dexpanthenol or cause skin dryness, which may counteract its healing properties.
• Systemic interactions: No known systemic drug interactions have been reported, as absorption through intact skin is minimal.

If you are using other prescribed skin medications or undergoing dermatologic treatments, consult a doctor before starting DEXANOL. Always follow professional guidance to avoid undesirable interactions or reduced efficacy.

Dosage of DEXANOL 5%

The dosage of DEXANOL 5% Cream depends on the severity and extent of the skin condition. The standard recommended dosing includes:

• Adults and Children: Apply a thin layer to the affected area 1 to 3 times per day or as needed.
• Infants (e.g., for diaper rash): Apply during each diaper change after thorough cleaning and drying of the area.
• Breastfeeding mothers (e.g., for cracked nipples): Apply after each feeding. Rinse before breastfeeding if advised.

DEXANOL may be used long-term for chronic dryness or short-term for acute irritation. No cumulative dosing risk is known with topical use. However, overuse may lead to excessive moisture accumulation (maceration), which may delay healing in some cases.

Possible side effects of DEXANOL 5%

DEXANOL 5% is generally well-tolerated. Side effects are rare and usually mild when they occur. However, users should remain observant for potential skin reactions.

• Common (less than 1%): Mild burning, redness, itching, or stinging at the site of application.
• Uncommon: Local allergic reactions such as rash, hives, or contact dermatitis.
• Rare: Anaphylactic-type reactions have not been reported with topical forms but may occur theoretically in hypersensitive individuals.

If any unusual reaction occurs or if the condition worsens during treatment, discontinue use and consult your doctor or pharmacist. Do not apply to infected, deep, or actively bleeding wounds unless specifically instructed.

DEXANOL 5% Contraindications DEXANOL 5%

DEXANOL 5% Cream is contraindicated in the following situations:

• Known hypersensitivity: Allergy to Dexpanthenol or any of the excipients in the formulation.
• Severe skin infections: Do not use on infected wounds or skin with active bacterial or fungal infections unless prescribed by a healthcare provider.
• Open or deep wounds: Not intended for use on deep puncture wounds, animal bites, or serious burns unless under medical advice.

In cases of pre-existing skin diseases, like eczema or psoriasis, consult a dermatologist before using DEXANOL 5% Cream as part of your skincare regimen.

Storage of DEXANOL 5%

Proper storage of DEXANOL 5% Cream ensures product stability and efficacy over its shelf life.

• Temperature: Store below 25°C (77°F). Do not freeze.
• Packaging: Keep the tube tightly closed after each use to prevent contamination and drying out.
• Environment: Store in a dry place, away from direct sunlight, heat sources, and moisture.
• Keep out of reach of children: Especially if used in households with infants or toddlers.

Do not use DEXANOL beyond the expiry date printed on the packaging. If any change in appearance, smell, or texture is observed, discard the product safely.