DESIRETT 75 mcg Tablets/Film-coated

What is DESIRETT 75 mcg

DESIRETT 75 mcg is a progestin-only oral contraceptive, primarily formulated with desogestrel. This medication is particularly known for its effectiveness in preventing pregnancy through multiple mechanisms. First, it works by inhibiting ovulation, thereby preventing the release of an egg from the ovary. This is achieved by suppressing the luteinizing hormone (LH) surge that typically triggers ovulation during the menstrual cycle.

In addition to inhibiting ovulation, DESIRETT also thickens the cervical mucus, creating a barrier that reduces sperm penetration and subsequently lowers the likelihood of fertilization. The alteration of the cervical mucus is an essential mechanism that contributes to the contraceptive efficacy of the drug.

Furthermore, DESIRETT has an effect on the endometrial lining. By thinning the lining of the uterus, the drug makes it less receptive to a fertilized egg, reducing the chance of implantation. These combined actions—ovulation inhibition, cervical mucus thickening, and endometrial alteration—make DESIRETT a highly effective method of contraception when used as directed.

The film-coated tablets are designed to be easy to swallow, offering convenience to users. DESIRETT is particularly advantageous for women who cannot use combined oral contraceptives due to estrogen-related health concerns, making it a versatile option. Unlike combined pills, DESIRETT is a progestin-only pill (POP) and can be used by breastfeeding women, provided they consult their healthcare provider.

It is important to note that while DESIRETT is highly effective at preventing pregnancy, it does not offer protection against sexually transmitted infections (STIs). Therefore, women who are at risk of contracting STIs should consider additional protective methods such as condoms.

Clinical studies have demonstrated that DESIRETT, when used properly, has a very high efficacy rate in preventing pregnancy. It is also associated with fewer side effects compared to combined oral contraceptives, particularly those related to estrogen.

Women who choose DESIRETT should maintain regular consultations with their healthcare provider to monitor their response to the medication and to ensure that it remains the best choice for their contraceptive needs. Understanding the comprehensive actions of DESIRETT helps users make informed decisions about their reproductive health.

How to use DESIRETT 75 mcg

How to Use DESIRETT 75 mcg: The administration of DESIRETT requires strict adherence to the dosing schedule to maximize its efficacy as a contraceptive. The tablets should be taken once daily, at the same time every day, regardless of meal times. Consistency is critical, as missing a dose can increase the risk of pregnancy.

• Daily Routine: Women should establish a routine where they take the tablet at the same time each day. This helps to maintain stable hormone levels and ensures continuous contraceptive protection.
• Missed Dose: If a woman forgets to take a tablet and remembers within 12 hours of the usual time, she should take the missed tablet as soon as possible and then take the next one at the regular time. If it has been more than 12 hours, the missed tablet should be skipped, and the next tablet should be taken as scheduled. Additionally, a backup contraceptive method, such as condoms, should be used for the next 7 days to ensure protection.
• Backup Contraception: In situations where two or more doses are missed, it is advised to use backup contraception until the normal dosing schedule is resumed. If unprotected sex occurs during this period, emergency contraception may be considered, depending on individual circumstances.
• Swallowing the Tablet: The film-coated tablet should be swallowed whole with water and not chewed or broken before swallowing. This helps ensure proper absorption of the active ingredient, desogestrel.
• Storage and Handling: Store DESIRETT in a cool, dry place and out of reach of children. Ensure that each blister is protected from light and moisture, which could degrade the active ingredient.

Healthcare providers will often recommend reminders, such as setting alarms or using apps to track the dosing schedule. Women should be encouraged to attend regular follow-ups to ensure that the medication is being used correctly and effectively.

Mode of Action DESIRETT 75 mcg

Mechanism of Action: The mechanism of action of DESIRETT is multifaceted, working primarily by preventing ovulation. Desogestrel, the active ingredient, mimics the effects of the naturally occurring hormone progesterone, altering the body’s hormone balance. This action prevents the surge of luteinizing hormone (LH) that would normally trigger the release of an egg during the menstrual cycle.

• Ovulation Inhibition: DESIRETT effectively suppresses ovulation in most users, thereby reducing the likelihood of pregnancy. This action is considered the primary contraceptive mechanism, and it is highly effective when the medication is taken correctly.
• Cervical Mucus Thickening: Desogestrel thickens the cervical mucus, which becomes less penetrable to sperm. This additional barrier reduces the chance of fertilization if ovulation does occur, offering a secondary line of contraceptive protection.
• Endometrial Alteration: DESIRETT also induces changes in the endometrial lining, making it thinner and less suitable for implantation of a fertilized egg. This further reduces the likelihood of pregnancy.

In summary, DESIRETT’s ability to prevent pregnancy is the result of three complementary actions—ovulation suppression, cervical mucus thickening, and endometrial alteration. These mechanisms work together to provide effective contraceptive protection. Women should understand that these actions are dependent on proper adherence to the medication regimen.

DESIRETT 75 mcg Interactions DESIRETT 75 mcg

Interactions with Other Medications: Like many oral contraceptives, DESIRETT can interact with certain medications, potentially reducing its efficacy. It is important for women to disclose all medications, including over-the-counter drugs and supplements, to their healthcare provider.

• Enzyme-Inducing Drugs: Medications such as rifampicin, certain anticonvulsants (e.g., carbamazepine), and herbal supplements like St. John's Wort can increase the metabolism of desogestrel, reducing its contraceptive efficacy. Women taking these medications should consider using alternative or additional contraception methods.
• Antibiotics: While most antibiotics do not interfere with DESIRETT, some, such as rifampicin and griseofulvin, may reduce its effectiveness. Women prescribed antibiotics should discuss the need for backup contraception with their healthcare provider.
• Other Hormonal Treatments: Women using other hormonal therapies should exercise caution, as these can interact with DESIRETT and alter its effectiveness. Regular follow-ups can help ensure safe and effective use of DESIRETT in combination with other treatments.

Women should keep an updated list of all medications they are taking and provide it to their healthcare provider during consultations to avoid potential drug interactions.

Dosage of DESIRETT 75 mcg

Recommended Dosage: The recommended dosage for DESIRETT 75 mcg is one tablet taken daily, at the same time each day. This regular dosing schedule is critical to maintaining stable levels of desogestrel in the body and ensuring its contraceptive efficacy.

• Daily Use: Women should be advised to take one tablet every day without interruption, even during menstruation. This continuous dosing schedule helps maintain the contraceptive effect throughout the menstrual cycle.
• Missed Dose: If a dose is missed, and less than 12 hours have passed since the usual time, the missed tablet should be taken as soon as remembered. The next tablet should be taken at the regular time. If more than 12 hours have passed, the woman should skip the missed dose and continue with the next tablet as scheduled, using backup contraception for the next 7 days.
• Handling Missed Doses: Women who miss two or more doses should use a backup contraceptive method and consult their healthcare provider for further guidance.

Proper adherence to the dosing schedule is essential for maintaining the effectiveness of DESIRETT. Women should be encouraged to set reminders or use pill trackers to help ensure they do not miss doses.

Possible side effects of DESIRETT 75 mcg

Potential Side Effects: DESIRETT 75 mcg is associated with several potential side effects, although most women tolerate the medication well. Common side effects include headaches, breast tenderness, and irregular bleeding.

• Headaches: Some women may experience mild to moderate headaches during the initial phase of treatment. These headaches typically subside as the body adjusts to the medication.
• Breast Tenderness: Breast tenderness is a common side effect that usually occurs during the first few months of use. Women should report any persistent or severe breast pain to their healthcare provider.
• Irregular Bleeding: DESIRETT can cause changes in menstrual bleeding patterns, including spotting or missed periods. While irregular bleeding is not uncommon, it generally stabilizes over time. Women who experience prolonged or heavy bleeding should consult their healthcare provider.
• Mood Changes: Some women may experience mood swings or changes in emotional well-being. These symptoms are typically mild and resolve as the body adjusts to the medication.
• Acne: In rare cases, women may experience acne flare-ups while taking DESIRETT. However, this side effect is generally mild and resolves without the need for additional treatment.

Women should be encouraged to report any unusual or severe side effects to their healthcare provider, as adjustments to the medication may be necessary.

DESIRETT 75 mcg Contraindications DESIRETT 75 mcg

Information not available.

Storage of DESIRETT 75 mcg

Storage Instructions: Proper storage of DESIRETT is essential to maintain its efficacy and safety. The medication should be stored in a cool, dry place at room temperature, away from direct sunlight and moisture.

• Temperature Control: The optimal storage temperature for DESIRETT is between 15°C and 30°C (59°F to 86°F). Exposure to extreme temperatures can degrade the active ingredient, reducing the effectiveness of the medication.
• Protection from Light and Moisture: DESIRETT should be kept in its original blister packaging to protect the tablets from environmental factors such as light and moisture, which can reduce the stability of desogestrel.
• Keep Out of Reach of Children: As with all medications, DESIRETT should be stored in a secure location that is out of reach of children to prevent accidental ingestion.
• Disposal of Expired Medication: Patients should regularly check the expiration date on the packaging and properly dispose of any expired medication according to local guidelines. Expired medication should not be used, as its effectiveness may be compromised.

Patients should be encouraged to consult their healthcare provider or pharmacist if they have any questions about the storage or disposal of DESIRETT. Proper storage practices help ensure that the medication remains effective throughout its shelf life.