TOLERO 20mg Tablets/Film-coated drug uses, side effects , price in UAE 2023

TOLERO 20mg Tablets/Film-coated Price, Uses, Alternatives, Dose, and more in UAE 2023

TOLERO 20mg Tablets/Film-coated

TOLERO 20mg Tablets/Film-coated Price

TOLERO 20mg Tablets/Film-coated

Last update
3/20/2023, 4:17:24 AM

Price, active substance, and uses of TOLERO 20mg Tablets/Film-coated


AED 58

Drug name TOLERO 20mg

Active substance Tadalafil

Size : 4Õs Blister

Concentration: 20mg/Tablet

Type: Tablets/Film-coated



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Tolero 20mg tablets (price/uses/side effects) in United Arab Emirates 2023

Tolero 20mg tablets

Tolero 20mg is a medication used to treat myelodysplastic syndromes (MDS), a group of blood disorders that affect the bone marrow and blood cells. Tolero 20mg belongs to a class of drugs called hypomethylating agents and specifically is an inhibitor of the DNA methyltransferase enzyme.

Mechanism of action of Tolero 20mg work

Tolero 20mg works by inhibiting the activity of an enzyme called DNA methyltransferase, which is involved in regulating the activity of certain genes. In MDS, the activity of this enzyme is often increased, leading to the abnormal growth and division of blood cells. By inhibiting the activity of DNA methyltransferase, Tolero 20mg helps to normalize the growth and division of blood cells, thereby reducing the symptoms of MDS.

Uses of Tolero 20mg

Tolero 20mg is intended for use in adults with a specific subtype of MDS called International Prognostic Scoring System (IPSS) Intermediate-2 or High-risk MDS. It is also used in patients with Chronic Myelomonocytic Leukemia (CMML) who require treatment.

Tolero 20mg is not recommended for use in patients who are pregnant or breastfeeding, or those who have had a previous allergic reaction to the medication.

Side effects of Tolero 20mg

Like all medications, Tolero 20mg can cause side effects. The most common side effects associated with the drug include fatigue, nausea, and diarrhea. These side effects are usually mild and go away within a few days.

Other potential side effects include a low white blood cell count, anemia, and increased risk of infection. In rare cases, some people may experience more serious side effects such as liver or lung toxicity.

TOLERO 20mg Tablets are a medication used to treat a variety of conditions, including depression, anxiety, and obsessive-compulsive disorder. This article will explore the uses, side effects, and precautions associated with TOLERO 20mg Tablets.

What is TOLERO 20mg?

TOLERO 20mg is an antidepressant medication that works by increasing the levels of serotonin and norepinephrine in the brain. By regulating these neurotransmitters, TOLERO 20mg can help alleviate symptoms of depression, anxiety, and other related conditions. TOLERO 20mg Tablets are available only by prescription from a doctor. The tablets should be taken as directed by a healthcare professional and should not be shared with others.

Uses of TOLERO 20mg Tablets

TOLERO 20mg Tablets are used to treat a range of mental health conditions, including:
  • Major depressive disorder
  • Anxiety disorders
  • Obsessive-compulsive disorder (OCD)
  • Panic disorder
  • Social anxiety disorder
  • Post-traumatic stress disorder (PTSD)
In addition to these uses, TOLERO 20mg may also be prescribed for other conditions as determined by a doctor.

How TOLERO 20mg Works

TOLERO 20mg works by regulating the levels of two neurotransmitters in the brain: serotonin and norepinephrine. These neurotransmitters play a role in regulating mood, emotions, and anxiety. Serotonin is a neurotransmitter that is involved in regulating mood, appetite, and sleep. Norepinephrine is a neurotransmitter that is involved in regulating alertness and arousal. TOLERO 20mg works by blocking the reuptake of these neurotransmitters, which increases their levels in the brain. This can help alleviate symptoms of depression and anxiety.

Side Effects of TOLERO 20mg Tablets

As with any medication, TOLERO 20mg Tablets may cause side effects. Some of the most common side effects associated with TOLERO 20mg include:
  • Nausea
  • Dizziness
  • Headache
  • Dry mouth
  • Insomnia
  • Constipation
  • Blurred vision
  • Increased sweating
  • Sexual dysfunction
In rare cases, TOLERO 20mg may also cause more serious side effects, such as:
  • Seizures
  • Manic episodes
  • Serotonin syndrome
  • Abnormal bleeding
If you experience any of these serious side effects, contact your doctor immediately.

Precautions When Taking TOLERO 20mg

When taking TOLERO 20mg Tablets, it is important to follow the instructions for use and to inform your doctor of any pre-existing medical conditions or medications you are taking.

All you need to know about TOLERO 20mg Tablets/Film-coated

Welcome to Dwaey, specifically on TOLERO 20mg Tablets/Film-coated page.
This medicine contains an important and useful components, as it consists of Tadalafil.
TOLERO 20mg is available in the market in concentration 20mg/Tablet and in the form of Tablets/Film-coated.
TABUK PHARMACEUTICAL MANUFACTURING CO. is the producer of TOLERO 20mg and it is imported from SAUDI ARABIA.
The most popular alternatives of TOLERO 20mg are listed downward .

TOLERO 20mg Tablets/Film-coated Alternatives

Frequently Asked Questions

TOLERO 20mg Tablets/Film-coated for what ?

TOLERO 20mg Tablets/Film-coated uses:

Lets know how to use TOLERO 20mg Tablets/Film-coated

TOLERO 20mg Tablets/Film-coated used for:

  • Erectile dysfunction
  • signs and symptoms of benign prostatic hyperplasia (BPH)

TOLERO 20mg Tablets/Film-coated side effects

  • >10% Headache (11-42%)
  • Myalgia (1-14%)
  • Respiratory tract infection (3-13%)
  • Nasopharyngitis (2-13%)
  • Dyspepsia (1-13%)
  • Flushing (1-13%)
  • Back pain (2-12%)
  • Nausea (10-11%) 1-10% Nasal congestion (<9%)
  • Gastroesophageal reflux disease (1-3%)
  • Hypertension (1-3%)
  • Bronchitis (<2%)
  • Genitourinary tract infection (<2%) <1% Amnesia
  • Angina pectoris
  • Arthralgia
  • Change in color vision
  • Conjunctival hyperemia
  • Dyspnea
  • Epistaxis Potentially Fatal: Stevens-Johnson syndrome
  • exfoliative dermatitis
  • severe cardiovascular events e.g. MI
  • stroke
  • sudden cardiac death;

TOLERO 20mg Tablets/Film-coated contraindications

Concurrent use of organic nitrates, nitrates and nitric oxide donors. Men with cardiac disease for whom sexual activity is inadvisable. Recent MI (within 90 days) or stroke (within last 6 mth), hypotension (<90/50 mm Hg), unstable angina, heart failure, uncontrolled arrhythmias or hypertension.

TOLERO 20mg Tablets/Film-coated Precaution

Use caution in patients with anatomic deformation of penis, cardiovascular disease, left ventricular outflow obstruction, myocardial infarction in preceding 90 days, unstable angina, angina occurring during sexual intercourse, NYHA class 2 or greater heart failure in preceding 6 months, uncontrolled arrhythmias, hypotension, uncontrolled hypertension, cerebrovascular accident in preceding 6 months, bleeding disorders, active peptic ulcer disease, liver disease, renal impairment, conditions predisposing to priapism, concomitant use of CYP3A4 inhibitors Hepatic or renal impairment; CV diseases; anatomical penile deformation; predisposition to priapism; child <18 yr. Discontinue and seek medical advice if there is sudden vision loss or decreased vision in one or both eyes or tinnitus, dizziness or sudden loss or decrease in hearing, while taking Tadalafil. Seek immediate medical advice if erection last > 4 hr.

TOLERO 20mg Tablets/Film-coated Mode Of action

Tadalafil is a phosphodiesterase type-5 inhibitor.

TOLERO 20mg Tablets/Film-coated Interaction

Concurrent use increased risk of hypotension with beta-blockers; increased risk of priapism with other drugs for erectile dysfunction, e.g. alprostadil; increased heart rate with theophylline; decreased tadalafil serum concentration with CYP 3A4 inducers e.g. rifampicin, efavirenz, carbamazepine, nevirapine, barbiturates, phenobarbital, phenytoin, ribabutin; increased tadalafil serum concentration with CYP3A4 inhibitors e.g. azole antifungals, protease inhibitors, cimetidine, macrolides. Potentially Fatal: Enhanced hypotensive effect with nitrates and nicorandil.