PANOXYL 5% Topical Lotion

What is PANOXYL 5%

PANOXYL 5% is a topical lotion that contains 5% Benzoyl Peroxide, an effective and widely used treatment for mild to moderate acne. It is applied directly to the skin and is available in a 30ml plastic bottle. Benzoyl peroxide is an over-the-counter and prescription-strength active ingredient that targets acne-causing bacteria and excess oil on the skin.

• Generic name: Benzoyl Peroxide
• Form: Topical lotion
• Strength: 5%
• Volume: 30ml plastic bottle

PANOXYL 5% helps in reducing blackheads, whiteheads, pimples, and inflammation associated with acne. It is particularly beneficial for patients with oily or acne-prone skin and is often used as part of a complete skincare routine under the guidance of a healthcare professional or dermatologist.

Due to its antibacterial, keratolytic, and comedolytic properties, PANOXYL is considered one of the most effective non-prescription treatments for acne vulgaris.

How to use PANOXYL 5%

Proper application of PANOXYL 5% is essential for achieving the desired results while minimizing skin irritation. Always follow the directions provided by your doctor or the instructions on the label.

• Preparation: Wash your hands before and after applying the lotion.
• Cleanse skin: Gently wash the affected area with a mild cleanser and pat dry with a soft towel.
• Application: Apply a thin layer of the lotion to the entire affected area once or twice daily.
• Frequency: Start with once daily. If well-tolerated, you may increase to twice daily after a few days.
• Avoid sensitive areas: Do not apply on broken, irritated, or sunburned skin, or near eyes, mouth, or mucous membranes.
• Wash hands: After application, wash hands thoroughly to prevent accidental contact with eyes or clothing.

Some patients may experience slight redness, peeling, or dryness during the first few weeks. These are common and often subside with continued use. A non-comedogenic moisturizer can help relieve dryness. Always consult your doctor if irritation becomes severe or persistent.

Mode of Action PANOXYL 5%

The therapeutic effects of Benzoyl Peroxide in PANOXYL 5% are due to its antimicrobial and exfoliative actions. It targets the root causes of acne: bacteria, blocked pores, and excess oil.

• Antibacterial effect: Benzoyl peroxide penetrates the skin and releases oxygen. This oxygen kills Cutibacterium acnes (formerly Propionibacterium acnes), the bacteria responsible for acne inflammation.
• Keratolytic action: It helps loosen and remove dead skin cells from the surface, reducing clogged pores and preventing comedone (blackheads and whiteheads) formation.
• Sebum regulation: Although not directly altering sebum production, it helps reduce oil accumulation and associated bacterial growth.
• Anti-inflammatory effect: It reduces redness and swelling around acne lesions by controlling the bacterial-induced immune response.

This multi-mechanism approach makes PANOXYL 5% an effective and reliable first-line treatment in acne management. However, it works best with consistent use and may take several weeks to show full results.

PANOXYL 5% Interactions PANOXYL 5%

Although PANOXYL 5% is used topically, it can still interact with other products applied to the skin, potentially increasing irritation or diminishing efficacy. Being aware of these interactions can help avoid adverse skin reactions.

• Other topical acne treatments:
  • Using PANOXYL with other strong agents like retinoids (e.g., tretinoin, adapalene) or salicylic acid can lead to increased skin dryness, peeling, or redness.
• Cosmetic products:
  • Avoid alcohol-based toners, astringents, or harsh exfoliants while using PANOXYL, as these may increase irritation.
• Sunscreens and moisturizers:
  • Use oil-free, non-comedogenic products to avoid aggravating acne.
• Whitening agents:
  • Products containing hydroquinone may be affected by benzoyl peroxide, leading to temporary staining of the skin or clothing.

Important: Benzoyl peroxide may bleach fabrics (clothing, towels, bedsheets). Use with care and avoid contact with colored materials. Always check with your healthcare provider before combining PANOXYL with other prescription or over-the-counter skin products.

Dosage of PANOXYL 5%

The dosage of PANOXYL 5% depends on the severity of acne, skin sensitivity, and the patient’s response to treatment. It is generally started at a lower frequency and adjusted based on tolerance.

• Initial application: Apply once daily in the evening after cleansing. This helps assess your skin’s sensitivity to the product.
• Maintenance dose: If tolerated well, the frequency may be increased to twice daily (morning and evening).
• Amount: A pea-sized amount is sufficient for the affected area. Avoid overuse, as excessive application does not improve results and may cause irritation.
• Duration: Most patients begin to see improvement within 2–4 weeks. Maximum effect may take up to 8–12 weeks.
• Combination therapy: In moderate to severe acne, PANOXYL may be used alongside topical or oral antibiotics, retinoids, or hormonal treatments as directed by a dermatologist.

Never apply more than recommended. Overuse may lead to skin dryness, irritation, and flaking. Consistent daily use, even when acne appears to improve, helps maintain clear skin and prevent new breakouts.

Possible side effects of PANOXYL 5%

PANOXYL 5% is generally well-tolerated when used appropriately, but some individuals may experience mild to moderate skin reactions, especially during the first few weeks of treatment.

• Common side effects:
  • Dryness or tightness of the skin
  • Peeling or flaking
  • Redness and itching
  • Mild stinging or burning sensation
• Less common side effects:
  • Skin discoloration (temporary)
  • Sun sensitivity or phototoxic reaction
  • Bleaching of hair or clothing due to product residue
• Serious side effects (rare):
  • Severe allergic reaction (rash, swelling, severe burning)
  • Contact dermatitis (skin blistering, intense itching)

To minimize irritation, start with once-daily application and gradually increase as tolerated. Discontinue use and consult a healthcare provider if severe irritation, allergic reaction, or worsening of acne occurs.

PANOXYL 5% Contraindications PANOXYL 5%

While PANOXYL 5% is safe for most individuals, there are some situations where it should not be used or should be used with caution.

• Absolute contraindications:
  • Hypersensitivity to benzoyl peroxide or any component of the formulation
• Relative contraindications or precautions:
  • Severely damaged or sunburned skin
  • History of eczema or atopic dermatitis (use with caution)
  • Concurrent use of other irritating topical products (e.g., retinoids, salicylic acid)
  • Use near mucous membranes, eyes, or lips

Before starting PANOXYL, consult a healthcare provider if you are pregnant, breastfeeding, or have a history of allergic skin reactions. Conduct a patch test before the first application by applying a small amount to a limited area and observing for 24 hours.

Storage of PANOXYL 5%

Proper storage ensures the efficacy and stability of PANOXYL 5%. It should be kept under suitable environmental conditions and out of reach of children.

• Temperature: Store at room temperature between 15°C to 25°C (59°F to 77°F).
• Light and moisture: Protect from direct sunlight and excessive moisture. Do not store in bathrooms.
• Container: Keep the bottle tightly closed when not in use. Store in its original container.
• Keep out of reach of children and pets.
• Do not use: After the expiration date mentioned on the label.
• Disposal: Do not pour unused lotion down the drain or toilet. Dispose of it through a pharmacist or local waste disposal authority.

Incorrect storage may reduce product effectiveness or increase skin irritation risk. Always refer to the packaging or consult a pharmacist for specific storage guidelines.