PANBIGEL Micro-enema Rectal Gel

What is PANBIGEL Micro-enema

PANBIGEL Micro-enema is a rectal gel formulated with a combination of Gelatine, Glycerine, and Purified Bile Extract. It is primarily used as a localized laxative to relieve occasional constipation and promote bowel evacuation, especially in preparation for diagnostic procedures such as sigmoidoscopy or rectal examinations.

• Gelatine acts as a lubricant and softener, helping to ease stool passage.
• Glycerine is a known osmotic agent that draws water into the bowel, softening stool and stimulating rectal contraction.
• Purified Bile Extract enhances the peristaltic movement of the rectum by stimulating mucosal secretion.

This micro-enema is supplied in a 5g tube format, typically sold in packs of 6 tubes, and is designed for single-use administration for fast and effective relief.

How to use PANBIGEL Micro-enema

Proper usage of PANBIGEL Micro-enema ensures optimal results while minimizing discomfort or potential complications. Always follow your healthcare provider’s instructions and the product leaflet.

• Wash your hands thoroughly before and after application.
• Lay down on your left side with your knees drawn toward the chest for easy insertion.
• Break the seal of the tube if present, and gently insert the nozzle into the rectum.
• Squeeze the full contents of the 5g tube slowly into the rectum.
• Withdraw the tube while still applying slight pressure to ensure the full dose is delivered.
• Remain lying down for a few minutes to allow the gel to work effectively.

Relief typically occurs within 15 to 30 minutes after application. Do not use more than one tube per day unless advised by your doctor. Avoid prolonged use without medical supervision.

Mode of Action PANBIGEL Micro-enema

PANBIGEL works through a triple mechanism to facilitate rectal evacuation:

• Lubrication (Gelatine): Gelatine acts by coating the stool and the rectal wall, making the passage of fecal matter smoother and less irritating to the mucosa.
• Osmotic Action (Glycerine): Glycerine draws water from surrounding tissues into the rectum. This softens the stool and increases volume, which in turn stimulates the bowel to contract and expel its contents.
• Stimulation (Purified Bile Extract): Bile salts stimulate mucosal secretion and enhance peristaltic reflexes, helping the lower bowel initiate evacuation more effectively.

This synergistic action provides gentle yet rapid relief from constipation, without systemic absorption, making it suitable even for individuals who require localized rectal care without systemic laxative effects.

PANBIGEL Micro-enema Interactions PANBIGEL Micro-enema

PANBIGEL Micro-enema is generally considered safe due to its localized action and minimal systemic absorption. However, it’s still important to consider potential interactions, especially in sensitive individuals or those on specific medications.

• No known drug-drug interactions have been clinically significant due to the non-systemic nature of the product.
• Do not use alongside other rectal products (e.g., suppositories, enemas, or rectal creams) unless directed by your physician, as this may increase rectal irritation or interfere with absorption.
• Inform your doctor if you are using diuretics, corticosteroids, or medications that affect electrolyte balance, although these interactions are minimal with topical rectal products.
• Using PANBIGEL excessively with other laxatives may lead to dependency or reduced bowel function over time.

Always disclose your full medication list to your healthcare provider before initiating any rectal product, even if it is over-the-counter.

Dosage of PANBIGEL Micro-enema

The standard dosage of PANBIGEL Micro-enema is designed to provide effective relief while minimizing the risk of irritation or overuse.

• Adults and adolescents (12 years and older): One tube (5g) rectally, as needed, preferably in the morning or before a medical procedure.
• Children under 12 years: Use only under medical supervision. Dosage adjustments may be necessary based on age and body weight.
• Frequency: Do not use more than once daily unless directed by a physician.
• Duration: Short-term use only. If constipation persists beyond 5–7 days, consult your healthcare provider to investigate underlying causes.

Misuse or overuse may result in reduced natural bowel function or dependency. Always consult a healthcare provider for chronic constipation or if using alongside other laxative therapies.

Possible side effects of PANBIGEL Micro-enema

PANBIGEL is generally well-tolerated, but like all medications, it may cause some side effects, especially with improper or prolonged use.

• Common side effects:
  • Mild rectal irritation or burning sensation upon administration
  • A transient feeling of urgency or discomfort
  • Abdominal cramping
• Less common side effects:
  • Mucosal dryness or inflammation if used repeatedly
  • Local allergic reactions (e.g., itching, rash)
• Rare but serious reactions:
  • Rectal bleeding or persistent pain
  • Severe irritation or signs of infection

If you experience any severe or persistent symptoms, discontinue use and seek medical attention promptly. Avoid using if allergic to any of the ingredients listed.

PANBIGEL Micro-enema Contraindications PANBIGEL Micro-enema

PANBIGEL should not be used in individuals with certain medical conditions or sensitivities. Consult your doctor before use in the following scenarios:

• Hypersensitivity or allergy to gelatine, glycerine, bile extracts, or any excipients in the formulation.
• Active inflammatory bowel conditions such as ulcerative colitis or Crohn’s disease during flare-ups.
• Rectal bleeding of unknown origin or conditions like hemorrhoids or anal fissures if symptoms are severe.
• Bowel obstruction or ileus: Using a rectal stimulant in a blocked intestine may worsen symptoms or cause complications.
• Children under 2 years: Safety has not been established unless directed by a pediatrician.

Patients with chronic constipation should not rely on repeated use without medical evaluation. Use caution in elderly patients or those with reduced rectal tone.

Storage of PANBIGEL Micro-enema

Proper storage ensures the efficacy and safety of the PANBIGEL Micro-enema over its shelf life.

• Store at a temperature between 15°C to 25°C (59°F to 77°F).
• Do not freeze. Exposure to freezing temperatures can degrade the formulation.
• Keep the product in its original packaging to protect it from light and moisture.
• Keep out of reach of children and pets.
• Do not use the product after the expiration date printed on the tube or box.
• Discard any unused portion after opening; each tube is intended for single-use only.

Improper storage can affect the consistency and effectiveness of the gel. If the product appears discolored, dried out, or altered in any way, do not use it.