OST-D3 50000 IU Tablets

What is OST-D3 50000 IU

OST-D3 50000 IU is a high-strength vitamin D3 (cholecalciferol) supplement formulated to treat and prevent vitamin D deficiency in individuals with significantly low levels. Each tablet provides 50,000 International Units (IU) of cholecalciferol, making it suitable for therapeutic correction under medical supervision.

• Generic Name: Cholecalciferol (Vitamin D3)
• Form: Oral tablet
• Strength: 50000 IU per tablet
• Packaging: 30 tablets in HDPE bottle
• Category: Nutritional Supplement / Fat-soluble Vitamin

OST-D3 50000 IU is commonly used for:

• Treatment of vitamin D deficiency and insufficiency
• Prevention of rickets and osteomalacia
• Support in bone health, especially in osteoporosis management
• Enhancing calcium and phosphorus absorption
• Improving immune and neuromuscular function

Its use should be guided by serum vitamin D levels and under the advice of a healthcare provider due to the potency of the formulation.

How to use OST-D3 50000 IU

OST-D3 50000 IU should be taken strictly as prescribed. Due to its high potency, it is not intended for regular daily supplementation without supervision.

• Route: Oral – swallow the tablet whole with water.
• Timing: Best taken with a fat-containing meal for better absorption (as Vitamin D is fat-soluble).
• Frequency: Usually prescribed once weekly, or bi-weekly depending on the degree of deficiency.

Important Usage Guidelines:

• Do not crush, chew, or break the tablet unless advised.
• Ensure regular monitoring of serum 25(OH)D and calcium levels during therapy.
• Avoid overdose—vitamin D toxicity can cause serious complications.

If a dose is missed:

• Take it as soon as remembered unless it's close to the next dose.
• Do not double the dose to catch up.

Always follow up with your healthcare provider to assess response to treatment and adjust the dose accordingly.

Mode of Action OST-D3 50000 IU

Cholecalciferol, the active ingredient in OST-D3 50000 IU, is a precursor to the active form of vitamin D in the body. It plays a vital role in maintaining bone health and metabolic balance.

• Metabolic Pathway:
  • Cholecalciferol is converted in the liver to 25-hydroxyvitamin D [25(OH)D], a storage form.
  • It is further activated in the kidneys to 1,25-dihydroxyvitamin D (calcitriol), the biologically active form.
• Physiological Functions of Calcitriol:
  • Enhances calcium and phosphate absorption in the gut
  • Promotes calcium reabsorption in the kidneys
  • Regulates parathyroid hormone (PTH) secretion
  • Supports bone remodeling and immune function

Ultimately, OST-D3 50000 IU restores optimal vitamin D levels, helping to prevent bone demineralization, support muscle function, and regulate immune responses.

OST-D3 50000 IU Interactions OST-D3 50000 IU

OST-D3 50000 IU can interact with a variety of medications, altering its absorption or increasing the risk of toxicity. Inform your doctor about all drugs, vitamins, and supplements you're taking.

• Calcium supplements: May increase the risk of hypercalcemia when used concurrently with high-dose vitamin D.
• Thiazide diuretics: Can reduce urinary calcium excretion, increasing the risk of hypercalcemia.
• Glucocorticoids: May impair vitamin D metabolism, reducing its effectiveness.
• Antiepileptics (phenytoin, phenobarbital): Increase vitamin D degradation, lowering its efficacy.
• Cholestyramine and Orlistat: Impair absorption of fat-soluble vitamins including D3.
• Digoxin: High calcium levels from vitamin D toxicity may increase the risk of cardiac arrhythmias with digoxin.

Dietary and Herbal Considerations:

• Magnesium and phosphorus levels should be balanced during therapy.
• St. John’s Wort and other CYP inducers may reduce vitamin D effectiveness.

Always seek medical advice before initiating OST-D3 50000 IU if on long-term medication.

Dosage of OST-D3 50000 IU

The dose of OST-D3 50000 IU should be individualized based on the severity of vitamin D deficiency, age, comorbid conditions, and lab findings.

• Adults (treatment of deficiency): 1 tablet (50000 IU) once weekly for 6–8 weeks.
• Maintenance dose: One tablet monthly or every two weeks, as advised by a physician.
• Osteoporosis support: Used intermittently with calcium supplements under guidance.

Special Populations:

• Elderly: Often require vitamin D due to reduced skin synthesis and absorption.
• Pregnant and lactating women: Use only when benefits outweigh risks; lower doses are preferred.
• Chronic kidney disease patients: Require specialized dosing due to altered vitamin D metabolism.

Lab Monitoring: Periodic blood tests are essential to check 25(OH)D and calcium levels, especially during long-term therapy. Over-supplementation may lead to hypercalcemia, renal issues, and vascular calcification.

Possible side effects of OST-D3 50000 IU

OST-D3 50000 IU is generally well tolerated, but as with any high-dose vitamin supplement, it may cause adverse effects if misused or taken in excess.

• Common Side Effects:
  • Gastrointestinal discomfort (nausea, vomiting)
  • Loss of appetite
  • Constipation
  • Mild fatigue or drowsiness
• Serious Side Effects (Usually due to overdose):
  • Hypercalcemia – symptoms include confusion, muscle weakness, excessive thirst, frequent urination
  • Kidney stones or kidney damage
  • Calcification of soft tissues
• Allergic Reactions (Rare):
  • Skin rash, itching
  • Swelling of the face or throat
  • Breathing difficulties

Seek immediate medical attention if any signs of allergic reaction or vitamin D overdose appear. Regular lab monitoring minimizes risk.

OST-D3 50000 IU Contraindications OST-D3 50000 IU

OST-D3 50000 IU should not be used in certain medical conditions where high-dose vitamin D could pose a health risk. Evaluation by a healthcare provider is necessary before starting therapy.

• Hypersensitivity: Allergy to cholecalciferol or tablet components.
• Hypercalcemia: Elevated blood calcium levels.
• Hypervitaminosis D: Already high vitamin D levels make supplementation harmful.
• Severe renal impairment or renal stones: Increased risk of calcium-phosphate imbalance and calcification.
• Sarcoidosis and other granulomatous diseases: Can cause endogenous overproduction of vitamin D.

Use with caution in:

• Patients with cardiovascular disease (due to calcium effects)
• Pregnant/lactating women unless supervised
• Children or adolescents unless specifically prescribed

If contraindications are present, alternative therapies or lower-dose formulations should be considered.

Storage of OST-D3 50000 IU

Proper storage of OST-D3 50000 IU ensures the medicine remains effective and safe for use throughout its shelf life.

• Storage temperature: Keep in a cool, dry place between 15°C to 25°C (59°F to 77°F).
• Avoid moisture: Store in a dry area—do not keep in bathrooms.
• Protect from light: Keep away from direct sunlight or excessive heat.
• Keep sealed: Always close the HDPE bottle tightly after use.
• Child safety: Store out of reach of children to avoid accidental ingestion.
• Do not use expired tablets: Check the expiration date and discard properly.

Do not dispose of unused or expired tablets in household waste. Use a proper pharmaceutical take-back program if available in your area.