OST-D3 25000 IU Tablets

What is OST-D3 25000 IU

OST-D3 25000 IU is a high-dose vitamin D3 supplement containing cholecalciferol, which is the natural form of vitamin D produced in human skin after exposure to sunlight. Each tablet delivers 25,000 International Units (IU) of cholecalciferol, making it suitable for correcting vitamin D deficiency and replenishing stores in individuals with significantly low levels.

• Generic Name: Cholecalciferol (Vitamin D3)
• Brand Name: OST-D3 25000 IU
• Form: Oral tablets
• Packaging: 30 tablets per HDPE bottle
• Classification: Vitamin supplement (fat-soluble)

OST-D3 25000 IU is typically prescribed for:

• Vitamin D deficiency or insufficiency
• Osteomalacia and rickets
• Supportive treatment for osteoporosis
• Improving calcium and phosphorus absorption
• Boosting immune system health

It is especially beneficial for individuals who get limited sun exposure, have malabsorption disorders, or follow restrictive diets lacking in vitamin D-rich foods.

How to use OST-D3 25000 IU

OST-D3 25000 IU should be used exactly as prescribed by your healthcare provider. Due to its high potency, it is not intended for daily use unless directed by a physician.

• Route: Oral – swallow the tablet whole with a full glass of water.
• With food: Best taken with a fat-containing meal to enhance absorption, as Vitamin D3 is fat-soluble.
• Dosage frequency: Commonly prescribed once a week or once every two weeks, depending on deficiency severity.

General instructions:

• Do not crush or chew the tablet unless directed.
• Take at the same time each scheduled day for consistency.
• Do not exceed the prescribed dose; vitamin D overdose can be harmful.

Missed dose: If you miss a dose, take it as soon as you remember. If it's close to your next scheduled dose, skip the missed one. Never take a double dose to compensate.

Consult your healthcare provider regularly to monitor your vitamin D levels and adjust the dosage if necessary.

Mode of Action OST-D3 25000 IU

Cholecalciferol (Vitamin D3), the active ingredient in OST-D3 25000 IU, plays a vital role in regulating calcium and phosphorus levels in the body, essential for healthy bones, teeth, and immune function.

• Conversion in the body:
  • Cholecalciferol is initially inactive.
  • In the liver, it is converted into 25-hydroxyvitamin D (calcidiol).
  • In the kidneys, it is further converted to the active form, 1,25-dihydroxyvitamin D (calcitriol).
• Physiological effects of active vitamin D:
  • Enhances intestinal absorption of calcium and phosphate.
  • Promotes bone mineralization and remodeling.
  • Regulates parathyroid hormone (PTH) levels to prevent bone loss.
  • Supports immune response and anti-inflammatory processes.

In summary, cholecalciferol ensures optimal calcium homeostasis, preventing bone disorders like rickets and osteomalacia while supporting broader metabolic and immune health.

OST-D3 25000 IU Interactions OST-D3 25000 IU

OST-D3 25000 IU may interact with various medications and supplements, affecting its absorption, metabolism, or increasing the risk of side effects. Inform your healthcare provider of all substances you use.

• Calcium supplements: May increase risk of hypercalcemia if taken concurrently without monitoring.
• Thiazide diuretics (e.g., hydrochlorothiazide): Can increase calcium levels, heightening hypercalcemia risk when combined with vitamin D.
• Corticosteroids: May reduce vitamin D effectiveness and calcium absorption.
• Antiepileptic drugs (e.g., phenytoin, phenobarbital): Can increase vitamin D metabolism, reducing efficacy.
• Cholestyramine or orlistat: Reduce fat absorption, potentially impairing vitamin D3 absorption.
• Digoxin: Increased calcium levels may enhance digoxin toxicity—monitor closely if used together.

Herbal and dietary considerations:

• Magnesium supplements may also interact with vitamin D metabolism—coordination is advised.
• High-phosphate foods or phosphate binders may alter mineral balance.

Always consult a physician or pharmacist before combining supplements or medications with OST-D3 25000 IU.

Dosage of OST-D3 25000 IU

OST-D3 25000 IU is a high-dose supplement typically used for treating moderate to severe vitamin D deficiency. Dosage must be tailored individually based on clinical evaluation and lab results (e.g., serum 25(OH)D levels).

• Adults (general deficiency treatment): One tablet (25,000 IU) weekly for 6–8 weeks.
• Maintenance therapy: One tablet every 2–4 weeks once adequate levels are restored.
• Osteoporosis support: May be given intermittently with calcium supplementation.
• Elderly patients: Same dose applies, but with closer calcium level monitoring due to increased sensitivity.

Special populations:

• Pregnant or breastfeeding women: Only under medical supervision—usually lower doses preferred.
• Renal impairment: Dosing requires caution due to altered metabolism and risk of hypercalcemia.

Lab monitoring: Repeat vitamin D and calcium levels every 6–12 weeks to guide therapy continuation or adjustment.

Never self-prescribe or use OST-D3 25000 IU for extended periods without supervision, as excessive vitamin D can lead to toxicity.

Possible side effects of OST-D3 25000 IU

OST-D3 25000 IU is generally well tolerated when used as prescribed. However, high doses of vitamin D can lead to certain side effects, especially with prolonged or unsupervised use.

• Common side effects:
  • Nausea
  • Loss of appetite
  • Dry mouth or metallic taste
  • Fatigue or weakness
• Less common but serious effects (usually due to overdose or long-term use):
  • Hypercalcemia (high blood calcium)
  • Kidney stones
  • Excessive thirst and frequent urination
  • Confusion or mental fog
• Allergic reactions (rare):
  • Rash or itching
  • Swelling of face, lips, or throat
  • Difficulty breathing

Seek medical attention if symptoms of overdose or allergic reactions occur. It is essential to use OST-D3 25000 IU under medical supervision with appropriate lab testing.

OST-D3 25000 IU Contraindications OST-D3 25000 IU

OST-D3 25000 IU should not be used in certain medical conditions where vitamin D3 supplementation may pose a health risk. Always consult your healthcare provider before starting therapy.

• Known hypersensitivity: Allergy to cholecalciferol or any ingredient in the tablet.
• Hypercalcemia: Already elevated calcium levels can worsen with vitamin D3 intake.
• Hypervitaminosis D: A condition of excessive vitamin D levels—additional supplementation is harmful.
• Severe renal impairment: Increases the risk of calcium-phosphate imbalance or soft tissue calcification.
• Sarcoidosis or other granulomatous disorders: Can increase sensitivity to vitamin D and lead to hypercalcemia.

Use with caution:

• Patients taking thiazide diuretics or digoxin
• Pregnant or lactating women
• Patients with a history of kidney stones

All contraindications should be discussed with your healthcare provider and vitamin D therapy should be discontinued if any contraindicated condition develops during use.

Storage of OST-D3 25000 IU

To ensure OST-D3 25000 IU tablets remain potent and safe, proper storage conditions are crucial.

• Temperature: Store at controlled room temperature, ideally between 15°C – 25°C (59°F – 77°F).
• Humidity: Keep the bottle tightly closed and away from high humidity—do not store in bathrooms.
• Light: Protect from direct sunlight or excessive heat exposure.
• Child safety: Store out of the reach and sight of children to prevent accidental ingestion.
• Expiration: Check the label for expiry date and discard tablets after that time.

Do not use tablets that show changes in appearance (e.g., discoloration, crumbling). For safe disposal of unused or expired medications, follow local regulations or return to a pharmacy.