ALLAIR 5mg Chewable tablet

What is ALLAIR 5mg

ALLAIR is a chewable tablet containing **5 mg montelukast sodium**, part of the leukotriene receptor antagonist class. It's primarily used to manage and prevent chronic asthma symptoms and relieve allergic rhinitis in children aged 6 to 14 years.

• Drug class: Leukotriene receptor antagonist (LTRA).
• Indications: Maintenance treatment of mild to moderate persistent asthma, prevention of exercise-induced bronchoconstriction, and relief of seasonal or perennial allergic rhinitis in the specified pediatric group :contentReference[oaicite:1]{index=1}.
• Form & packaging: Cherry-flavored chewable tablets provided in 10-tablet blisters (total 30 tablets per pack).
• Administration route: Oral chewable tablet, swallowed completely after chewing.
• Approved age group: Specifically formulated for children 6–14 years; other age groups (2–5 years or ≥15 years) use different strengths/forms :contentReference[oaicite:2]{index=2}.

How to use ALLAIR 5mg

• Dosing: One 5 mg chewable tablet orally once daily, ideally administered in the evening for asthma control :contentReference[oaicite:3]{index=3}.
• With or without food: Can be taken regardless of meals.
• For exercise-induced bronchoconstriction: One 5 mg tablet ≥2 hrs before exercise; do not exceed one dose in 24 hrs :contentReference[oaicite:4]{index=4}.
• Missed dose: Skip it and resume next day at usual time—do not double dose :contentReference[oaicite:5]{index=5}.
• Treatment duration: Taken daily as maintenance therapy; abrupt cessation requires physician guidance.
• Do not use as a rescue medication: Not effective for acute asthma attacks—always have a rescue inhaler available :contentReference[oaicite:6]{index=6}.

Ensure adherence for optimal symptom control—chew thoroughly and swallow. Inform caregivers about its correct use.

Mode of Action ALLAIR 5mg

• Leukotriene receptor blockade: Montelukast selectively antagonizes the cysteinyl leukotriene receptor CysLT₁, thus inhibiting bronchoconstriction, mucus secretion, vascular permeability, and inflammation :contentReference[oaicite:7]{index=7}.
• Prevention of bronchospasm: Effective in reducing both spontaneous and exercise-induced airway narrowing :contentReference[oaicite:8]{index=8}.
• Anti-inflammatory effect: Decreases eosinophilic infiltration in airways and nasal passages, relieving asthma and allergy symptoms :contentReference[oaicite:9]{index=9}.
• Clinical benefits: Improves peak expiratory flow, reduces asthma exacerbations and rescue inhaler use, and alleviates nasal congestion and sneezing :contentReference[oaicite:10]{index=10}.

By targeting the leukotriene pathway, ALLAIR provides targeted control of airway inflammation and symptom prevention in pediatric respiratory conditions.

ALLAIR 5mg Interactions ALLAIR 5mg

• Minimal clinically significant interactions: Montelukast isn’t known to interact significantly with theophylline, warfarin, or corticosteroids :contentReference[oaicite:11]{index=11}.
• CYP2C8 substrates: As a CYP2C8 inhibitor, montelukast may increase levels of drugs like amodiaquine, though this effect is generally minor :contentReference[oaicite:12]{index=12}.
• CYP inducers/inhibitors: Phenobarbital or rifampin may alter montelukast levels—monitor clinical response :contentReference[oaicite:13]{index=13}.
• Aspirin-sensitive asthma: Avoid aspirin as montelukast does not protect against aspirin-induced attacks :contentReference[oaicite:14]{index=14}.
• Vaccines: No interaction—routine immunizations are safe during ALLAIR therapy.

Dosage of ALLAIR 5mg

• Children 6–14 years: 5 mg chewable tablet once daily in the evening :contentReference[oaicite:15]{index=15}.
• Exercise-induced bronchoconstriction (6–14 years): 5 mg single dose at least 2 hrs before activity—max one dose per 24 hrs :contentReference[oaicite:16]{index=16}.
• Other age groups:
  • 2–5 years: 4 mg chewable or granules
  • ≥15 years: 10 mg tablet :contentReference[oaicite:17]{index=17}.
• Renal impairment: No adjustment needed as excretion is hepatic :contentReference[oaicite:18]{index=18}.
• Hepatic impairment: No changes for mild-to-moderate disease; data lacking for severe cases and use cautiously :contentReference[oaicite:19]{index=19}.

Possible side effects of ALLAIR 5mg

• Common: Headache, abdominal pain, cough, fever, sore throat, runny nose, diarrhea, earache :contentReference[oaicite:20]{index=20}.
• Less common: Fatigue, muscle cramps, rash, paresthesia, sinusitis :contentReference[oaicite:21]{index=21}.
• Serious (rare):
  • Neuropsychiatric effects: sleep disturbances, mood changes, aggression, depression, suicidal thoughts—boxed warning applies :contentReference[oaicite:22]{index=22}.
  • Churg–Strauss syndrome (eosinophilic granulomatosis): especially if tapering steroids :contentReference[oaicite:23]{index=23}.
  • Severe hypersensitivity: angioedema, erythema multiforme :contentReference[oaicite:24]{index=24}.
  • Hepatic effects: rare elevation in liver enzymes or injury :contentReference[oaicite:25]{index=25}.

Monitor children for behavioral changes; report serious adverse events immediately and discontinue treatment where necessary.

ALLAIR 5mg Contraindications ALLAIR 5mg

• Hypersensitivity: Known allergy to montelukast or tablet excipients (e.g., aspartame, dyes) :contentReference[oaicite:26]{index=26}.
• Chewable tablets in PKU: Contain phenylalanine; avoid in phenylketonuria—use alternate formulation :contentReference[oaicite:27]{index=27}.
• Acute asthma attacks: Not a substitute for rescue medication :contentReference[oaicite:28]{index=28}.
• Neuropsychiatric disorders: Use caution in children with psychiatric history—risk-benefit assessment needed :contentReference[oaicite:29]{index=29}.

Storage of ALLAIR 5mg

• Temperature: Store at 20–25 °C (68–77 °F)—short excursions permitted :contentReference[oaicite:30]{index=30}.
• Packaging: Keep tablets in blister packs until use to protect from moisture and preserve freshness :contentReference[oaicite:31]{index=31}.
• Light and humidity: Store away from direct sunlight, heat, and damp environments.
• Child safety: Keep out of reach—chewable but toxic if misused.
• Expiry and disposal: Discard expired tablets responsibly—not flushed down the toilet :contentReference[oaicite:32]{index=32}.

Keep the packaging label for dosage and expiry info. Avoid storage in bathrooms or near sinks.