ALKA -SELTZER Tablets/Effervescent

What is ALKA -SELTZER

ALKA-SELTZER is a well-known over-the-counter (OTC) medication available in effervescent tablet form. It is primarily used to relieve symptoms of acid indigestion, heartburn, and upset stomach, often accompanied by headache or body aches. Each tablet contains a combination of the following active ingredients:

• Aspirin (Acetylsalicylic Acid): A nonsteroidal anti-inflammatory drug (NSAID) that relieves pain and reduces inflammation.
• Sodium Bicarbonate: A fast-acting antacid that helps neutralize excess stomach acid.
• Citric Acid: Reacts with sodium bicarbonate to produce effervescence, aiding in quick dissolution and absorption.

This combination allows ALKA-SELTZER to treat both gastrointestinal discomfort and pain such as headache or muscle aches. The effervescent nature of the tablets makes them easier on the stomach compared to traditional solid tablets.

How to use ALKA -SELTZER

ALKA-SELTZER should be used according to the product label or as directed by a healthcare provider. Below are the general guidelines for proper use:

• Dissolution: Dissolve 2 tablets completely in a glass (approx. 120-240 ml) of water. Wait until the fizzing stops before drinking.
• Dosage Frequency: You can repeat the dose every 4 hours if needed, but do not exceed 8 tablets in 24 hours unless directed by a physician.
• Timing: Best taken on a full stomach to minimize potential stomach irritation, particularly due to the aspirin content.
• Children: Not recommended for children under 12 years unless advised by a healthcare professional.
• Duration: Do not use for more than 10 days for pain or 3 days for fever without medical advice.

Always read the full patient information leaflet and consult a doctor or pharmacist if unsure about the appropriate use.

Mode of Action ALKA -SELTZER

Each ingredient in ALKA-SELTZER works in a distinct but complementary manner:

• Aspirin: Inhibits cyclooxygenase enzymes (COX-1 and COX-2), which are involved in the synthesis of prostaglandins. This leads to reduced inflammation, pain, and fever.
• Sodium Bicarbonate: A systemic antacid that neutralizes stomach acid (HCl), providing rapid relief from acid-related discomfort.
• Citric Acid: Reacts with sodium bicarbonate to produce carbon dioxide bubbles (effervescence). This not only aids tablet dissolution but may also enhance gastric emptying and absorption of the active ingredients.

The result is fast-acting relief from common gastrointestinal and musculoskeletal symptoms, making ALKA-SELTZER a versatile remedy for multi-symptom relief.

ALKA -SELTZER Interactions ALKA -SELTZER

ALKA-SELTZER contains aspirin, which interacts with a range of medications and substances. Notable interactions include:

• Anticoagulants (e.g., warfarin, heparin): Increased risk of bleeding due to the antiplatelet effects of aspirin.
• NSAIDs (e.g., ibuprofen, naproxen): Additive risk of gastrointestinal ulceration or bleeding.
• Corticosteroids (e.g., prednisone): May increase the risk of gastric irritation and ulceration when combined with aspirin.
• Antihypertensives (ACE inhibitors, diuretics): NSAIDs can reduce their effectiveness and increase the risk of renal impairment.
• Alcohol: Concomitant use increases the risk of gastrointestinal bleeding.
• SSRIs (e.g., fluoxetine, sertraline): Increased risk of bleeding due to platelet inhibition by both aspirin and SSRIs.

Always inform your healthcare provider or pharmacist about all medications, supplements, and herbal products you are using before starting ALKA-SELTZER.

Dosage of ALKA -SELTZER

The recommended dosage depends on the age and condition being treated. General dosage guidelines are as follows:

• Adults and children over 12 years: Dissolve 2 tablets in water every 4 hours as needed. Maximum dose: 8 tablets in 24 hours.
• Children under 12: Use only under medical supervision.
• For occasional use: ALKA-SELTZER should not be used continuously for more than 10 days for pain or 3 days for fever unless advised by a physician.

Consult a healthcare provider for patients with liver or kidney issues, as dose adjustments may be needed.

Possible side effects of ALKA -SELTZER

Although ALKA-SELTZER is generally well-tolerated when used as directed, it may cause side effects in some individuals. These can range from mild to serious:

• Common side effects: Nausea, heartburn, abdominal discomfort, or mild stomach upset.
• Allergic reactions: Rash, itching, swelling (especially of the face/tongue/throat), dizziness, or trouble breathing. Seek immediate medical help if any of these occur.
• Gastrointestinal bleeding: Indicated by black, tarry stools or vomiting blood; more likely with prolonged use or high doses.
• Tinnitus (ringing in the ears): May occur with overdose or sensitivity to aspirin.
• Reye's syndrome: A rare but serious condition in children and teenagers recovering from viral infections; do not use in this age group without doctor approval.

If any side effects are persistent or concerning, stop using the medication and consult a healthcare provider.

ALKA -SELTZER Contraindications ALKA -SELTZER

ALKA-SELTZER should not be used in the following situations:

• Hypersensitivity: Known allergy to aspirin, NSAIDs, or any other component of the product.
• Active peptic ulcer or gastrointestinal bleeding: Aspirin may exacerbate bleeding and ulceration.
• Severe renal or hepatic impairment: Use may further compromise organ function.
• Hemophilia or bleeding disorders: Aspirin's antiplatelet effect increases bleeding risk.
• Asthma triggered by NSAIDs: Some individuals experience bronchospasm with aspirin.
• Pregnancy (especially third trimester): Risk of fetal harm or prolonged labor.
• Children or teenagers with viral infections: Due to the risk of Reye’s syndrome.

Always assess patient history thoroughly before recommending or using ALKA-SELTZER.

Storage of ALKA -SELTZER

Proper storage of ALKA-SELTZER ensures its safety and effectiveness:

• Temperature: Store at room temperature, ideally between 20°C to 25°C (68°F to 77°F).
• Humidity: Keep in a dry place; protect from excessive moisture to preserve the effervescent quality.
• Container: Keep in the original packaging (sachet or blister) until use to avoid degradation.
• Light: Store away from direct sunlight or intense light exposure.
• Keep out of reach of children: To prevent accidental ingestion or overdose.

Do not use expired tablets, and dispose of unused medication properly in accordance with local pharmaceutical waste guidelines.