What is ALDARA 5%
ALDARA 5% is a topical immunomodulatory medication containing 5% imiquimod. Packaged in 250 mg sachets (twelve per box), it is a prescription cream used for:
- External genital and perianal warts (condylomata acuminata) in individuals aged 12 years and above :contentReference[oaicite:1]{index=1}.
- Actinic keratosis on the face or scalp in immunocompetent adults :contentReference[oaicite:2]{index=2}.
- Superficial basal cell carcinoma (sBCC) on trunk or extremities when surgery is unsuitable :contentReference[oaicite:3]{index=3}.
It is an immune response modifier, applied topically to stimulate local immunity. It's not directly antiviral or cytotoxic; rather, it harnesses the body's immune response :contentReference[oaicite:4]{index=4}. :contentReference[oaicite:5]{index=5}
How to use ALDARA 5%
- Clean application area: Gently wash with mild soap, pat dry, and apply before bedtime. Do not apply on inflamed or non-intact skin :contentReference[oaicite:6]{index=6}.
- Dosage based on indication:
- Warts: Apply once daily, 3× per week (e.g., Mon/Wed/Fri), leave on 6–10 hours, for up to 16 weeks :contentReference[oaicite:7]{index=7}.
- Actinic keratosis: Once daily, 2× per week (e.g., Mon/Thu), leave on ~8 hours, for 16 weeks :contentReference[oaicite:8]{index=8}.
- sBCC: Apply once daily, 5× per week for 6 weeks, on lesion plus a 1-cm margin :contentReference[oaicite:9]{index=9}.
- Post-application: Wash off with mild soap after the time elapses. Avoid occlusive dressings :contentReference[oaicite:10]{index=10}.
- Protect skin: Avoid sun exposure; use sunscreen, hats, and avoid tanning beds during treatment :contentReference[oaicite:11]{index=11}.
- Missed dose: If forgotten, skip it—do not double. Continue according to the prescribed schedule :contentReference[oaicite:12]{index=12}.
Mode of Action ALDARA 5%
Imiquimod is a toll-like receptor 7 (TLR7) agonist. Here's how it works:
- Immune activation: Stimulates TLR7 on dendritic cells and macrophages to produce cytokines—IFN‑α, TNF‑α, IL‑6, IL‑12—that initiate a local immune response :contentReference[oaicite:13]{index=13}.
- Langerhans cell migration: These antigen-presenting cells migrate to lymph nodes to support adaptive immunity :contentReference[oaicite:14]{index=14}.
- Antitumoral and antiviral effects: Cytokines create an environment toxic to abnormal or virus-infected cells, leading to lesion clearance :contentReference[oaicite:15]{index=15}.
- Local usage: Designed to act on skin lesions with little to no systemic absorption—serum half-life ~30 hours only if absorbed topically :contentReference[oaicite:16]{index=16}.
ALDARA 5% Interactions ALDARA 5%
There are minimal drug interactions due to low systemic absorption. Key considerations include:
- Drug interactions: No known significant interactions with oral medications :contentReference[oaicite:17]{index=17}.
- Topical agents: Concurrent use of other topical treatments (e.g., corticosteroids, retinoids, fluorouracil) may alter efficacy or increase irritation—discuss with your provider.
- Skin conditions: Avoid use over eczema or sunburned skin due to potential for excessive inflammation :contentReference[oaicite:18]{index=18}.
- Autoimmune diseases: May exacerbate conditions such as psoriasis or graft-versus-host disease—use with caution :contentReference[oaicite:19]{index=19}.
Dosage of ALDARA 5%
Specific dosing depends on the condition being treated:
- External genital/perianal warts: Apply once daily, 3× per week for up to 16 weeks, each for 6–10 hours :contentReference[oaicite:20]{index=20}.
- Actinic keratosis: Apply once daily, 2× per week for 16 weeks, 8-hour applications :contentReference[oaicite:21]{index=21}.
- Superficial BCC: Apply once daily, 5× per week for 6 weeks; target lesion + 1 cm margin :contentReference[oaicite:22]{index=22}.
- Pediatric use: ≥12 years for warts; safety for other uses not established :contentReference[oaicite:23]{index=23}.
- Discontinuation: Stop after cycles are complete or if severe reactions occur; consult your doctor before restarting.
Possible side effects of ALDARA 5%
Local skin reactions are common and often anticipated; systemic effects are rarer but possible:
- Local reactions (common): Erythema, edema, scabbing, crusting, ulceration, burning, pain, itching, scaling, erosion, exudate :contentReference[oaicite:24]{index=24}.
- Flu-like symptoms: Headache, fever, fatigue, chills, muscle aches, nausea, diarrhea :contentReference[oaicite:25]{index=25}.
- Serious local reactions: Severe ulceration, erosion, or weeping—may require treatment interruption :contentReference[oaicite:26]{index=26}.
- Allergic reactions: Rare anaphylaxis or hives—discontinue and seek emergency care if event occurs :contentReference[oaicite:27]{index=27}.
- Systemic complications (rare): Capillary leak syndrome, exacerbation of autoimmune conditions, lymph node swelling :contentReference[oaicite:28]{index=28}.
- Pediatric effects: Application in children may reduce white blood cell and neutrophil counts; use caution :contentReference[oaicite:29]{index=29}.
ALDARA 5% Contraindications ALDARA 5%
- Hypersensitivity: Allergy to imiquimod or formulation excipients :contentReference[oaicite:30]{index=30}.
- Broken skin: Avoid use on open wounds, ulcers, eczema, or sunburned areas :contentReference[oaicite:31]{index=31}.
- Autoimmune conditions: Use with caution in psoriasis or active graft-versus-host disease :contentReference[oaicite:32]{index=32}.
- Pregnancy: FDA class C—use only if benefits outweigh risks :contentReference[oaicite:33]{index=33}.
- Breastfeeding: Unknown if imiquimod passes into breast milk—avoid contact with infant skin :contentReference[oaicite:34]{index=34}.
- Immunocompromised: Efficacy and safety not established in immunosuppressed individuals :contentReference[oaicite:35]{index=35}.
Storage of ALDARA 5%
- Temperature: Store at room temperature (20–25 °C). Do not freeze or refrigerate :contentReference[oaicite:36]{index=36}.
- Packaging: Keep sachets sealed until use in original box to protect from moisture and light.
- Expiration: Discard unused sachets after the expiry date.
- Safety: Keep out of reach of children. Avoid eye contact; wash hands thoroughly post-application :contentReference[oaicite:37]{index=37}.
- Disposal: Do not flush. Use take-back programs or follow local regulations :contentReference[oaicite:38]{index=38}.
ALDARA 5% features an exceptional active ingredient renowned for its potent effects, comprising Imiquimod. This powerful formulation provides a superior solution for addressing diverse health concerns. With 50mg/g concentration and an easily manageable Cream, it remains a preferred option for countless individuals seeking effective treatment.
Introduction
All you need to know about ALDARA 5% .
Welcome to Dwaey, specifically on ALDARA 5% page.
This medicine contains an important and useful components, as it consists of Imiquimod.
ALDARA 5% is available in the market in concentration 50mg/g and in the form of Cream.
3M HEALTH CARE LIMITED is the producer of ALDARA 5% and it is imported from UK,
The most popular alternatives of ALDARA 5% are listed downward .
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Active Substance
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Indications
- No indications available.
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Frequently Asked Questions
ALDARA 5% should be stored according to the instructions provided by 3M HEALTH CARE LIMITED.
In general, it is recommended to store ALDARA 5% in a cool, dry place, away from direct sunlight
and out of the reach of children.
The duration of treatment with ALDARA 5% may vary depending on the condition being treated
and the guidance of your healthcare provider. It is important to follow the prescribed treatment
plan and continue taking ALDARA 5% for the recommended duration, even if your symptoms improve.
If you have any concerns or questions about the duration of treatment, consult your healthcare provider.
It is important to check with your healthcare provider or read the medication label for specific
instructions regarding alcohol consumption while taking ALDARA 5%. Some medications, including
ALDARA 5%, may have interactions with alcohol that can reduce effectiveness, increase side
effects, or pose other risks to your health. It is best to follow the guidance provided by your
healthcare professional.
If you miss a dose of ALDARA 5%, take it as soon as you remember. However, if it is close
to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing
schedule. Do not take a double dose to make up for a missed one unless advised by your healthcare provider.
No, do not stop taking ALDARA 5% without consulting your healthcare provider, even if your
symptoms improve. It is important to complete the full course of treatment as prescribed. Stopping
the medication prematurely may lead to a relapse or incomplete resolution of the condition. If you
have concerns about the duration of treatment, consult your healthcare provider for guidance.
It is important to consult your healthcare provider before taking ALDARA 5% if you are
pregnant or breastfeeding. They will be able to assess the potential risks and benefits based on your
specific situation. Please note that the safety and suitability of ALDARA 5% during pregnancy
or breastfeeding may depend on the active substance [Active Substance], concentration 50mg/g,
and the specific recommendations of 3M HEALTH CARE LIMITED.
The effects of ALDARA 5% on your ability to drive or operate machinery can vary depending on
the active substance [Active Substance], concentration 50mg/g, and individual factors.
Some medications may cause drowsiness, dizziness, or other side effects that can impair your judgment
or coordination. It is important to read the medication label or consult your healthcare provider to
understand any potential effects on your ability to perform tasks that require alertness.
The instructions for taking ALDARA 5% with or without food may vary depending on the medication
and the recommendations of 3M HEALTH CARE LIMITED. Some medications may be more effective when taken with
food to enhance absorption or reduce stomach irritation, while others may need to be taken on an empty
stomach for optimal absorption. Read the medication label or consult your healthcare provider for specific instructions.
The use of ALDARA 5% in children or elderly individuals may depend on various factors, including
the specific medication, type Cream, and the recommendations of 3M HEALTH CARE LIMITED. Some
medications may have specific dosing instructions or precautions for these age groups. Consult your
healthcare provider or read the medication label for information regarding the safe and appropriate use
of ALDARA 5% in children or elderly individuals.
Dwaey
All medical information published on the Dwaey website aims to increase medical awareness and health education among users. However, it is not a substitute for professional medical advice. Always consult with a specialist doctor. We strongly advise against using any information or medicine found on the site without referring to your healthcare provider.
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