What is ALBUMIN NOVONORDISK 20%
ALBUMIN NOVONORDISK 20% is a sterile, hyperoncotic plasma expander containing human albumin at 200 g/L (20 %) in a 50 mL bottle. Extracted from pooled donor plasma, it undergoes rigorous viral inactivation (e.g., pasteurization) to ensure safety and sterility.
- Classification: Human albumin solution; colloid volume expander.
- Indications:
- Hypovolemia and hypovolemic shock
- Hypoalbuminemia in critically ill or bleeding patients
- Prevention of circulatory dysfunction post-paracentesis in cirrhosis
- Ovarian hyperstimulation syndrome (OHSS)
- ARDS as adjunct with diuretics
- Acute nephrosis unresponsive to diuretics
- Neonatal hyperbilirubinemia in exchange transfusion
- Packaging: Single-dose sterile 50 mL bottle with albumin and infusion set.
This product is reserved for clinical settings, administered under close monitoring by trained healthcare professionals.
How to use ALBUMIN NOVONORDISK 20%
Prior to administration, inspect the bottle. The solution should be clear to slightly opalescent; discard if cloudy or particulate is present. Allow it to reach room temperature before infusion.
- Route: Intravenous (IV) only, using aseptic technique.
- Infusion setup: Connect the provided infusion set. Do not dilute with water or mix with other IV fluids.
- Infusion rate:
- Typical: up to 1–2 mL/min (≈1g albumin per minute).
- If large volumes (>1500 mL) are needed, warm to room temperature.
- Monitoring: Track vitals (BP, HR), fluid status, and signs of overload. Adjust rate accordingly.
- Post-infusion: Discard unused portion and maintain sterility.
Repeated doses may be administered based on clinical response. Always tailor infusion speed and volume to the patient’s cardiovascular status to avoid complications. :contentReference[oaicite:1]{index=1}
Mode of Action ALBUMIN NOVONORDISK 20%
Human albumin plays multiple physiological roles, with the 20 % solution offering potent volume-expanding benefits:
- Oncotic pressure: High albumin concentration draws fluid from interstitial to intravascular compartments.
- Volume expansion: Each mL infused can mobilize 2–4 mL plasma volume—quickly restoring circulating volume in shock.
- Molecular transport: Binds and carries hormones, fatty acids, drugs (e.g., warfarin), and bilirubin.
- Buffering: Helps maintain plasma pH and electrolyte balance.
Overall, albumin improves hemodynamics, tissue perfusion, and supports fluid balance in critical conditions. Its colloid osmotic effect is especially useful when fluid restriction is necessary. :contentReference[oaicite:2]{index=2}
ALBUMIN NOVONORDISK 20% Interactions ALBUMIN NOVONORDISK 20%
Albumin infusions have a low risk of pharmacokinetic interactions, but certain considerations apply:
- Displacement of bound drugs: High-dose albumin can release drugs like warfarin or phenytoin, increasing free drug levels.
- ACE inhibitors: Combining with albumin may trigger hypotension—monitor blood pressure closely.
- Other colloids: Concomitant use with synthetic colloids may lead to hypovolemia or overload—avoid without monitoring.
- Electrolyte shifts: Volume shifts can dilute electrolytes—monitor sodium, potassium, calcium.
Interactions are mild experimentally; most risk comes from physiological effects of volume changes. Maintain close observation of vitals and drug levels when using with anticoagulants, diuretics, or in renal/cardiac impairment. :contentReference[oaicite:3]{index=3}
Dosage of ALBUMIN NOVONORDISK 20%
Dosing is individualized by weight, condition severity, and response.
- Hypovolemia: Adults: 25 g (~125 mL). Can repeat after 15–30 min if needed. Pediatric: 0.5–1 g/kg (≈25–50 mL/kg). :contentReference[oaicite:4]{index=4}
- Hypoalbuminemia: Adults: 50–75 g/day. Pediatric: ~25 g/day. :contentReference[oaicite:5]{index=5}
- Paracentesis: 8 g per 1000 mL ascites removed. :contentReference[oaicite:6]{index=6}
- ARDS: 25 g over 30 min, repeat every 8 hrs for 3 days. :contentReference[oaicite:7]{index=7}
- OHSS: 50–100 g over 4 hrs; repeat every 4–12 hrs as needed. :contentReference[oaicite:8]{index=8}
- Neonatal hyperbilirubinemia: 1 g/kg before/during exchange transfusion. :contentReference[oaicite:9]{index=9}
Do not exceed 2 g/kg/day. Monitor hemodynamics and labs during therapy. :contentReference[oaicite:10]{index=10}
Possible side effects of ALBUMIN NOVONORDISK 20%
While generally safe, albumin infusions can cause side effects ranging from common infusion-related symptoms to rare serious events:
- Mild reactions: Fever, chills, flushing, nausea. Often resolve with slower infusion. :contentReference[oaicite:11]{index=11}
- Hypotension: May result from rapid infusion or ACE inhibitor interaction—infuse slowly. :contentReference[oaicite:12]{index=12}
- Volume overload: Watch for pulmonary edema or heart failure in predisposed patients. :contentReference[oaicite:13]{index=13}
- Allergic/anaphylaxis: Urticaria, bronchospasm, rarely anaphylactic shock—infusion should be stopped immediately. :contentReference[oaicite:14]{index=14}
- Hemo-dilution: May dilute hematocrit—supplement blood if hemorrhage. :contentReference[oaicite:15]{index=15}
Monitor vitals and labs, especially in at-risk patients. Slow or stop infusion upon serious reactions. :contentReference[oaicite:16]{index=16}
ALBUMIN NOVONORDISK 20% Contraindications ALBUMIN NOVONORDISK 20%
Use is contraindicated or should be used with caution in the following scenarios:
- Absolute:
- Known hypersensitivity to human albumin or any excipients
- Severe anemia (can worsen oxygen delivery)
- Decompensated heart failure or pulmonary edema (risk of volume overload) :contentReference[oaicite:17]{index=17}
- Relative/caution:
- Renal impairment (risk of fluid retention)
- Hypertension
- Bleeding disorders
- Dehydration without hypovolemia
- Pregnant or lactating women (use only if benefit outweighs risk) :contentReference[oaicite:18]{index=18}
- Pediatrics needs special dosing and monitoring :contentReference[oaicite:19]{index=19}
Use only after careful clinical evaluation. Continuous monitoring is essential during administration.
Storage of ALBUMIN NOVONORDISK 20%
Storage Instructions:
- Keep between 2–25 °C (36–77 °F); do not freeze. :contentReference[oaicite:20]{index=20}
- Store in original container, protected from light.
- Avoid shaking to prevent protein denaturation or foaming.
Handling before use:
- Inspect visually for cloudiness or particulates; discard if abnormal.
- Do not dilute with non-approved solutions.
- Once opened, use immediately and discard unused portion. :contentReference[oaicite:21]{index=21}
Disposal: Follow biohazard/local regulations. Do not flush or discard with household waste.
ALBUMIN NOVONORDISK 20% features an exceptional active ingredient renowned for its potent effects, comprising Albumin (human). This powerful formulation provides a superior solution for addressing diverse health concerns. With 200mg/ml concentration and an easily manageable Infusion, it remains a preferred option for countless individuals seeking effective treatment.
Introduction
All you need to know about ALBUMIN NOVONORDISK 20% .
Welcome to Dwaey, specifically on ALBUMIN NOVONORDISK 20% page.
This medicine contains an important and useful components, as it consists of Albumin (human).
ALBUMIN NOVONORDISK 20% is available in the market in concentration 200mg/ml and in the form of Infusion.
NOVO NORDISK A/S is the producer of ALBUMIN NOVONORDISK 20% and it is imported from DENMARK,
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Frequently Asked Questions
ALBUMIN NOVONORDISK 20% should be stored according to the instructions provided by NOVO NORDISK A/S.
In general, it is recommended to store ALBUMIN NOVONORDISK 20% in a cool, dry place, away from direct sunlight
and out of the reach of children.
The duration of treatment with ALBUMIN NOVONORDISK 20% may vary depending on the condition being treated
and the guidance of your healthcare provider. It is important to follow the prescribed treatment
plan and continue taking ALBUMIN NOVONORDISK 20% for the recommended duration, even if your symptoms improve.
If you have any concerns or questions about the duration of treatment, consult your healthcare provider.
It is important to check with your healthcare provider or read the medication label for specific
instructions regarding alcohol consumption while taking ALBUMIN NOVONORDISK 20%. Some medications, including
ALBUMIN NOVONORDISK 20%, may have interactions with alcohol that can reduce effectiveness, increase side
effects, or pose other risks to your health. It is best to follow the guidance provided by your
healthcare professional.
If you miss a dose of ALBUMIN NOVONORDISK 20%, take it as soon as you remember. However, if it is close
to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing
schedule. Do not take a double dose to make up for a missed one unless advised by your healthcare provider.
No, do not stop taking ALBUMIN NOVONORDISK 20% without consulting your healthcare provider, even if your
symptoms improve. It is important to complete the full course of treatment as prescribed. Stopping
the medication prematurely may lead to a relapse or incomplete resolution of the condition. If you
have concerns about the duration of treatment, consult your healthcare provider for guidance.
It is important to consult your healthcare provider before taking ALBUMIN NOVONORDISK 20% if you are
pregnant or breastfeeding. They will be able to assess the potential risks and benefits based on your
specific situation. Please note that the safety and suitability of ALBUMIN NOVONORDISK 20% during pregnancy
or breastfeeding may depend on the active substance [Active Substance], concentration 200mg/ml,
and the specific recommendations of NOVO NORDISK A/S.
The effects of ALBUMIN NOVONORDISK 20% on your ability to drive or operate machinery can vary depending on
the active substance [Active Substance], concentration 200mg/ml, and individual factors.
Some medications may cause drowsiness, dizziness, or other side effects that can impair your judgment
or coordination. It is important to read the medication label or consult your healthcare provider to
understand any potential effects on your ability to perform tasks that require alertness.
The instructions for taking ALBUMIN NOVONORDISK 20% with or without food may vary depending on the medication
and the recommendations of NOVO NORDISK A/S. Some medications may be more effective when taken with
food to enhance absorption or reduce stomach irritation, while others may need to be taken on an empty
stomach for optimal absorption. Read the medication label or consult your healthcare provider for specific instructions.
The use of ALBUMIN NOVONORDISK 20% in children or elderly individuals may depend on various factors, including
the specific medication, type Infusion, and the recommendations of NOVO NORDISK A/S. Some
medications may have specific dosing instructions or precautions for these age groups. Consult your
healthcare provider or read the medication label for information regarding the safe and appropriate use
of ALBUMIN NOVONORDISK 20% in children or elderly individuals.
Dwaey
All medical information published on the Dwaey website aims to increase medical awareness and health education among users. However, it is not a substitute for professional medical advice. Always consult with a specialist doctor. We strongly advise against using any information or medicine found on the site without referring to your healthcare provider.
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