AIRFAST 4mg Tablets/Chewable

What is AIRFAST 4mg

AIRFAST 4mg is a chewable tablet formulation containing Montelukast sodium (equivalent to 4mg of Montelukast), a leukotriene receptor antagonist used in the management and prevention of asthma and allergic rhinitis. It is commonly prescribed for children aged 2 to 5 years.

• Belongs to the class of medications called leukotriene receptor antagonists.
• Indicated for the long-term management of asthma and to relieve symptoms of seasonal allergic rhinitis (hay fever).
• Especially useful for patients who experience exercise-induced bronchoconstriction.
• Formulated as chewable tablets, making it easier for pediatric use.
• Not intended for acute asthma attacks; rather, it is used as a preventive and maintenance therapy.

It is typically administered once daily in the evening to help reduce airway inflammation and bronchial hyperresponsiveness. Its use is guided by a healthcare provider’s assessment of the patient’s condition and response to therapy.

How to use AIRFAST 4mg

AIRFAST 4mg Chewable Tablets should be used exactly as directed by a healthcare professional. This medication is intended for children aged 2 to 5 years and must be taken regularly to be effective.

• Administration: The tablet should be chewed thoroughly before swallowing. Do not swallow whole.
• Timing: Administer once daily in the evening, with or without food.
• Consistency: Take at the same time each day to maintain consistent drug levels in the body.
• Missed dose: If a dose is missed, give it as soon as remembered. If it's almost time for the next dose, skip the missed one—do not double dose.
• Not for immediate relief: Do not use AIRFAST during an acute asthma attack. A fast-acting inhaler should be used instead.
• Allergen exposure: Can be used before anticipated allergen exposure (e.g., pollen season).
• Parental guidance: Parents should supervise children while taking the medication to ensure proper chewing and swallowing.

Always consult your child’s doctor before starting or stopping the medication and report any unusual symptoms during treatment.

Mode of Action AIRFAST 4mg

Montelukast, the active ingredient in AIRFAST 4mg, works by blocking leukotrienes—chemicals in the body that cause inflammation, bronchoconstriction, and mucus production in asthma and allergies.

• Leukotriene receptor antagonist: Specifically targets and blocks the cysteinyl leukotriene receptor type 1 (CysLT1) found in the airways and on inflammatory cells.
• Anti-inflammatory effect: Reduces inflammation in the airways, helping prevent asthma symptoms such as wheezing, coughing, and shortness of breath.
• Bronchoprotective effect: Prevents narrowing of the airways triggered by allergens or exercise.
• Improves respiratory function: Enhances overall control of asthma and reduces the frequency of exacerbations.
• Allergy symptom relief: Blocks nasal congestion, sneezing, runny nose, and itchy eyes by inhibiting leukotriene-mediated inflammation in the upper respiratory tract.

The therapeutic effects of AIRFAST are most noticeable after a few days of regular use, although some patients may begin to feel relief earlier. Its mechanism does not involve bronchodilation but instead focuses on inflammation prevention.

AIRFAST 4mg Interactions AIRFAST 4mg

Although Montelukast generally has a low potential for drug interactions, it is important to be aware of medications and substances that may affect its efficacy or safety.

• Phenytoin, Phenobarbital, and Rifampin: These are enzyme-inducing agents that can lower Montelukast levels, reducing its effectiveness.
• Gemfibrozil: May increase Montelukast levels in the blood due to inhibition of metabolism.
• Drugs metabolized by CYP450 enzymes: Montelukast is metabolized by CYP3A4, CYP2C8, and CYP2C9, but at therapeutic doses, it does not significantly inhibit or induce these enzymes.
• NSAIDs and Aspirin: While not a direct interaction, patients with aspirin-sensitive asthma should be monitored closely as these drugs may worsen asthma symptoms.
• Other asthma medications: AIRFAST can be safely used with inhaled corticosteroids, beta-agonists, and theophylline, but always under medical supervision.

Always inform your healthcare provider about all medications your child is taking, including over-the-counter drugs and supplements, to avoid potential interactions.

Dosage of AIRFAST 4mg

The dosage of AIRFAST 4mg is based on age, weight, and the condition being treated. It is specifically formulated for pediatric use.

• Children 2 to 5 years old: 4 mg once daily in the evening.
• Form: Chewable tablet, to be thoroughly chewed before swallowing.
• With or without food: Food does not significantly affect its absorption, so it can be taken with or without meals.
• In seasonal allergic rhinitis: Can be started just before the onset of allergy season and discontinued after the season ends.
• Exercise-induced bronchospasm: Should not be used as a single agent for this condition in children under 6 years.

Never exceed the prescribed dose. If symptoms persist or worsen, consult the healthcare provider promptly. Do not abruptly discontinue asthma medications without medical advice.

Possible side effects of AIRFAST 4mg

While most children tolerate AIRFAST 4mg well, some may experience side effects. Most are mild and temporary, but some may require medical attention.

• Common side effects:
• Abdominal pain
• Headache
• Thirst
• Diarrhea
• Upper respiratory tract infections
• Less common but serious effects:
• Mood or behavior changes (e.g., aggression, anxiety, irritability)
• Sleep disturbances (including nightmares or insomnia)
• Allergic reactions (rash, swelling, breathing difficulty)
• Hepatic dysfunction (very rare)
• Neuropsychiatric events: These have been reported in some children. Caregivers should observe for unusual changes in behavior.

Seek immediate medical attention if signs of a severe allergic reaction or mood changes appear. Always report any adverse effects to the prescribing physician.

AIRFAST 4mg Contraindications AIRFAST 4mg

AIRFAST 4mg is contraindicated in certain cases and should be used with caution in specific populations.

• Hypersensitivity: Contraindicated in patients with known allergy to Montelukast or any of the excipients.
• Acute asthma attacks: Not a substitute for fast-acting bronchodilators. Should not be used during acute asthma exacerbations.
• Hepatic impairment: Use with caution in patients with moderate to severe liver dysfunction due to hepatic metabolism of the drug.
• Neuropsychiatric history: Caution advised in children with a history of behavioral disorders or seizures.
• Phenylketonuria (PKU): The chewable tablet may contain aspartame, which is contraindicated in PKU.

A thorough medical evaluation should precede the use of AIRFAST to rule out any contraindications or risk factors that may compromise safety or efficacy.

Storage of AIRFAST 4mg

Proper storage of AIRFAST 4mg ensures the medication maintains its efficacy and safety throughout its shelf life.

• Temperature: Store at room temperature, ideally between 15°C to 30°C (59°F to 86°F).
• Humidity: Protect from excessive moisture. Keep the medication in its original blister packaging until use.
• Light protection: Store away from direct sunlight and heat sources.
• Child safety: Keep out of reach and sight of children to prevent accidental ingestion.
• Do not use after expiry: Check expiration date on the packaging and do not use past this date.
• Disposal: Do not flush unused tablets. Dispose of through a pharmacy or according to local guidelines for pharmaceutical waste.

Improper storage can degrade the active ingredient, reducing the drug’s effectiveness and possibly causing harm. Always follow the pharmacist’s or manufacturer’s instructions for optimal storage conditions.