AGIOLAX Granules

What is AGIOLAX

AGIOLAX is a herbal laxative granule formulation designed for the relief of constipation and the regulation of bowel movements. It combines the bulking and hydrating properties of fiber-rich components (Ispaghula husk and Plantago ovata seeds) with the stimulant effects of Tinnevelly Senna pods. This synergistic blend makes AGIOLAX suitable for both occasional and chronic constipation when used as directed.

• Active ingredients:
  • Ispaghula Husk (Psyllium Husk): A natural fiber that absorbs water and swells to form a gel-like mass, promoting stool bulk and motility.
  • Plantago ovata Seeds: Further contributes to fiber content and enhances mucilage formation.
  • Tinnevelly Senna Pods: Contains anthraquinone glycosides, which stimulate intestinal peristalsis and accelerate bowel emptying.
• Form: Granules
• Packaging: 250g Jar

AGIOLAX is commonly used by patients with constipation, hemorrhoids, or post-surgical bowel irregularities. It is suitable for adults and elderly patients but should be used under medical supervision in children.

How to use AGIOLAX

AGIOLAX should be used exactly as prescribed by a healthcare provider or as directed on the product label. It is typically taken orally with water.

• General Instructions:
  • Take 1 teaspoon (about 5g) once or twice daily, preferably in the evening.
  • Swallow the granules with a full glass of water (at least 150-200 ml).
  • Do not chew or crush the granules. They should be taken whole.
  • It is best taken after meals to avoid any potential gastric discomfort.
• Important Considerations:
  • Always take with adequate fluid to prevent intestinal obstruction.
  • Allow at least 6–8 hours for the laxative effect to manifest.
  • Not suitable for immediate relief of constipation symptoms.

Do not exceed the recommended dose unless directed by a doctor. Regular, prolonged use should be monitored by a healthcare professional to prevent dependency or electrolyte imbalance.

Mode of Action AGIOLAX

AGIOLAX exerts a combined laxative effect due to its unique combination of bulk-forming fibers and stimulant herbs.

• Ispaghula Husk:
  • Absorbs water and swells in the intestine, increasing stool volume and moisture.
  • This results in mechanical stimulation of peristalsis and facilitates easier defecation.
• Plantago ovata Seeds:
  • Acts synergistically with Ispaghula husk to improve mucilage content.
  • Enhances intestinal lubrication and supports the bulking process.
• Tinnevelly Senna Pods:
  • Contains anthraquinone glycosides (e.g., sennosides) that are metabolized by colonic bacteria into active metabolites.
  • These compounds irritate the colonic mucosa and stimulate contractions (peristalsis), promoting bowel emptying.

By combining a stimulant laxative with a bulk-forming agent, AGIOLAX ensures effective and more physiologic bowel regulation without causing abrupt bowel evacuation like harsh laxatives.

AGIOLAX Interactions AGIOLAX

AGIOLAX may interact with several medications, particularly due to its fiber content and stimulant laxative properties. Always inform your healthcare provider of all medications and supplements you are taking.

• Potential interactions include:
  • Digitalis glycosides (e.g., Digoxin): Senna-induced potassium loss can enhance digoxin toxicity.
  • Diuretics or corticosteroids: May potentiate electrolyte imbalance, especially hypokalemia.
  • Antidiabetic agents: Fiber may alter the absorption of oral antidiabetics, affecting blood glucose control.
  • Anticoagulants: High-fiber products may interfere with vitamin K absorption and the activity of warfarin.
  • Thyroid medications: Absorption of levothyroxine may be reduced; dose timing should be adjusted.
  • Oral medications: Fiber can reduce the absorption of various oral drugs if taken simultaneously.

To avoid these interactions, separate the administration of AGIOLAX and other oral medications by at least 2 hours.

Dosage of AGIOLAX

The dosage of AGIOLAX depends on the individual’s condition, age, and response to treatment. Below is the general guidance:

• Adults and adolescents (12 years and older):
  • One teaspoonful (approximately 5g) in the evening.
  • If needed, a second dose may be taken in the morning.
• Children under 12 years:
  • Use only under medical supervision.
• Geriatric patients:
  • Same adult dose; ensure adequate hydration to prevent dehydration.

Administration:

• Take with a full glass of water.
• Do not chew or crush the granules.
• Avoid taking AGIOLAX immediately before bed unless prescribed.

Adjust dosage only on medical advice. Prolonged use should not exceed 1–2 weeks unless under supervision.

Possible side effects of AGIOLAX

AGIOLAX is generally well tolerated when taken as recommended. However, as with all medications, side effects may occur.

• Common side effects:
  • Abdominal bloating or cramping
  • Flatulence (gas)
  • Loose stools or mild diarrhea, especially with higher doses
• Less common:
  • Nausea
  • Rectal discomfort
• Serious (rare):
  • Allergic reactions (rash, itching, swelling, difficulty breathing)
  • Electrolyte imbalances (especially hypokalemia with prolonged use)
  • Intestinal obstruction or impaction (if taken with insufficient fluids)

If any serious reaction occurs, discontinue use and seek immediate medical attention. Report any persistent side effects to your healthcare provider.

AGIOLAX Contraindications AGIOLAX

AGIOLAX is contraindicated in certain medical conditions and should not be used without professional guidance in specific populations.

• Do NOT use AGIOLAX if:
  • You have known hypersensitivity to Ispaghula, Senna, or any component of the product.
  • You suffer from intestinal obstruction or stenosis.
  • You have a history of intestinal atony or impaired bowel motility.
  • You have inflammatory bowel diseases such as Crohn’s disease or ulcerative colitis (in severe cases).
  • You are experiencing undiagnosed abdominal pain, nausea, or vomiting.
  • You are dehydrated or have an existing electrolyte imbalance.
• Use with caution:
  • In elderly patients or those prone to dehydration
  • In patients on concurrent medications that affect electrolyte balance
  • During pregnancy or lactation (only with medical advice)

Storage of AGIOLAX

Proper storage of AGIOLAX ensures product stability and efficacy throughout its shelf life.

• Storage guidelines:
  • Store in a cool, dry place below 25°C (77°F).
  • Keep the jar tightly closed after each use to protect from moisture and air exposure.
  • Do not refrigerate or freeze.
  • Keep away from direct sunlight and heat sources.
• Additional recommendations:
  • Keep out of reach of children.
  • Do not use after the expiration date printed on the jar.
  • Discard any product that shows signs of discoloration, clumping, or unusual odor.

Always check the packaging for specific storage instructions from the manufacturer.