What is AERRANE
AERRANE is the brand name for **isoflurane**, a **volatile halogenated ether inhalation anesthetic** used in medical and veterinary settings to induce and maintain general anesthesia:contentReference[oaicite:1]{index=1}.
- Appearance: Clear, colorless liquid in amber bottles (100 mL):contentReference[oaicite:2]{index=2}.
- Primary indication: General anesthesia induction and maintenance during surgery:contentReference[oaicite:3]{index=3}.
- Features: Nonflammable, pungent odor, rapid induction and recovery:contentReference[oaicite:4]{index=4}.
- Use: Administered via calibrated vaporizer by trained anesthesia professionals:contentReference[oaicite:5]{index=5}.
How to use AERRANE
Safe administration requires expertise and precision:
- Administration route: Inhaled via vaporizer; used with oxygen or nitrous oxide:contentReference[oaicite:6]{index=6}.
- Dosing:
- Induction: 1.5–3% vapor concentration, delivering anesthesia within 7–10 minutes:contentReference[oaicite:7]{index=7}.
- Maintenance: 1–2.5% with N₂O; may require additional concentration if used with oxygen alone:contentReference[oaicite:8]{index=8}.
- Monitoring: Continuous pulse oximetry, ECG, blood pressure, end-tidal CO₂, and ventilation:contentReference[oaicite:9]{index=9}.
- Professional setting: Only used by qualified anesthesiologists or certified providers with airway management capabilities:contentReference[oaicite:10]{index=10}.
Mode of Action AERRANE
Isoflurane induces anesthesia through central nervous system depression:
- Neurotransmitter effects: Enhances GABA_A and glycine receptor activity, inhibits NMDA receptors, and alters ion channel functions:contentReference[oaicite:11]{index=11}.
- Spinal cord action: Promotes skeletal muscle relaxation by modulating inhibitory spinal receptors:contentReference[oaicite:12]{index=12}.
- Cardiovascular effects: Reduces systemic vascular resistance, may lower blood pressure, slightly increases heart rate, and dilates coronary vessels:contentReference[oaicite:13]{index=13}.
- Respiratory effects: Depresses tidal volume, increases PaCO₂, and requires ventilatory support:contentReference[oaicite:14]{index=14}.
- Cerebral impact: Elevates cerebral blood flow and intracranial pressure at higher concentrations:contentReference[oaicite:15]{index=15}.
AERRANE Interactions AERRANE
Isoflurane’s interactions are significant in anesthetic management:
- Opioids/N₂O: Reduce the MAC of isoflurane, so dosing must be adjusted:contentReference[oaicite:16]{index=16}.
- Neuromuscular blockers: Potentiates their effect—use reduced doses:contentReference[oaicite:17]{index=17}.
- CYP interactions: Isoflurane doesn’t significantly interact metabolically, but co-use with cardiac QT-prolonging drugs (e.g., amiodarone, dronedarone) is contraindicated due to arrhythmia risk:contentReference[oaicite:18]{index=18}.
Dosage of AERRANE
Dosage is individualized and monitored continuously:
- Induction: 1.5–3% isoflurane vapor by inhalation:contentReference[oaicite:19]{index=19}.
- Maintenance: 1–2.5% with N₂O; add 0.5–1% if using oxygen only:contentReference[oaicite:20]{index=20}.
- Pediatric use: Safety under age 2 not established; monitor neurocognitive effects in infants during prolonged exposure:contentReference[oaicite:21]{index=21}.
- Elderly adjustments: MAC decreases ~6% per decade over 40 years—lower concentrations needed:contentReference[oaicite:22]{index=22}.
Possible side effects of AERRANE
Like other anesthetics, isoflurane’s adverse effects are dose-dependent:
- Common (>5%): Agitation, cough, breath-holding, nausea, shivering, vomiting, laryngospasm, delirium:contentReference[oaicite:23]{index=23}.
- Cardiovascular: Hypotension, arrhythmias, possible coronary steal syndrome:contentReference[oaicite:24]{index=24}.
- Respiratory: Depressed ventilation, bronchodilation, airway irritation:contentReference[oaicite:25]{index=25}.
- Cerebral & hepatic: Increased intracranial pressure; rare reports of hepatitis and hepatic necrosis:contentReference[oaicite:26]{index=26}.
- Rare but serious: Malignant hyperthermia, perioperative hyperkalemia in certain neuromuscular disorders:contentReference[oaicite:27]{index=27}.
AERRANE Contraindications AERRANE
AERRANE must not be used in certain patient populations:
- Known hypersensitivity to isoflurane or other halogenated anesthetics:contentReference[oaicite:28]{index=28}.
- History or susceptibility to malignant hyperthermia:contentReference[oaicite:29]{index=29}.
- Prior unexplained hepatitis after inhalational anesthetic use:contentReference[oaicite:30]{index=30}.
- Contraindicated for obstetric anesthesia except for Cesarean section use:contentReference[oaicite:31]{index=31}.
- Caution with neuromuscular diseases (e.g., Duchenne’s dystrophy), liver dysfunction, intracranial hypertension, and high cardiac risk:contentReference[oaicite:32]{index=32}.
Storage of AERRANE
Maintain proper storage to ensure efficacy and safety:
- Room temperature (15–30 °C); protect from light:contentReference[oaicite:33]{index=33}.
- Keep in original amber bottle to prevent light exposure:contentReference[oaicite:34]{index=34}.
- Do not freeze; stable under various conditions:contentReference[oaicite:35]{index=35}.
- Ensure vaporizers are filled and maintained by trained personnel only:contentReference[oaicite:36]{index=36}.
- Handle spill and waste per institutional and environmental regulations.
AERRANE features an exceptional active ingredient renowned for its potent effects, comprising Isoflurane. This powerful formulation provides a superior solution for addressing diverse health concerns. With 1 concentration and an easily manageable Inhalation/Liquid for, it remains a preferred option for countless individuals seeking effective treatment.
Introduction
All you need to know about AERRANE .
Welcome to Dwaey, specifically on AERRANE page.
This medicine contains an important and useful components, as it consists of Isoflurane.
AERRANE is available in the market in concentration 1 and in the form of Inhalation/Liquid for.
BAXTER CARIBE INC. is the producer of AERRANE and it is imported from PUERTO RICO,
The most popular alternatives of AERRANE are listed downward .
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Frequently Asked Questions
AERRANE should be stored according to the instructions provided by BAXTER CARIBE INC..
In general, it is recommended to store AERRANE in a cool, dry place, away from direct sunlight
and out of the reach of children.
The duration of treatment with AERRANE may vary depending on the condition being treated
and the guidance of your healthcare provider. It is important to follow the prescribed treatment
plan and continue taking AERRANE for the recommended duration, even if your symptoms improve.
If you have any concerns or questions about the duration of treatment, consult your healthcare provider.
It is important to check with your healthcare provider or read the medication label for specific
instructions regarding alcohol consumption while taking AERRANE. Some medications, including
AERRANE, may have interactions with alcohol that can reduce effectiveness, increase side
effects, or pose other risks to your health. It is best to follow the guidance provided by your
healthcare professional.
If you miss a dose of AERRANE, take it as soon as you remember. However, if it is close
to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing
schedule. Do not take a double dose to make up for a missed one unless advised by your healthcare provider.
No, do not stop taking AERRANE without consulting your healthcare provider, even if your
symptoms improve. It is important to complete the full course of treatment as prescribed. Stopping
the medication prematurely may lead to a relapse or incomplete resolution of the condition. If you
have concerns about the duration of treatment, consult your healthcare provider for guidance.
It is important to consult your healthcare provider before taking AERRANE if you are
pregnant or breastfeeding. They will be able to assess the potential risks and benefits based on your
specific situation. Please note that the safety and suitability of AERRANE during pregnancy
or breastfeeding may depend on the active substance [Active Substance], concentration 1,
and the specific recommendations of BAXTER CARIBE INC..
The effects of AERRANE on your ability to drive or operate machinery can vary depending on
the active substance [Active Substance], concentration 1, and individual factors.
Some medications may cause drowsiness, dizziness, or other side effects that can impair your judgment
or coordination. It is important to read the medication label or consult your healthcare provider to
understand any potential effects on your ability to perform tasks that require alertness.
The instructions for taking AERRANE with or without food may vary depending on the medication
and the recommendations of BAXTER CARIBE INC.. Some medications may be more effective when taken with
food to enhance absorption or reduce stomach irritation, while others may need to be taken on an empty
stomach for optimal absorption. Read the medication label or consult your healthcare provider for specific instructions.
The use of AERRANE in children or elderly individuals may depend on various factors, including
the specific medication, type Inhalation/Liquid for, and the recommendations of BAXTER CARIBE INC.. Some
medications may have specific dosing instructions or precautions for these age groups. Consult your
healthcare provider or read the medication label for information regarding the safe and appropriate use
of AERRANE in children or elderly individuals.
Dwaey
All medical information published on the Dwaey website aims to increase medical awareness and health education among users. However, it is not a substitute for professional medical advice. Always consult with a specialist doctor. We strongly advise against using any information or medicine found on the site without referring to your healthcare provider.
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