What is AERIUS 0.5mg/ml
AERIUS 0.5mg/ml is an oral solution formulation of Desloratadine, an antihistamine used to treat allergic conditions. Desloratadine is a second-generation H1-receptor antagonist known for its effectiveness in relieving symptoms associated with allergic rhinitis (hay fever) and chronic idiopathic urticaria (chronic hives).
- Active ingredient: Desloratadine at 0.5 mg per ml, designed for flexible dosing especially in pediatric and elderly patients.
- Indications: Used for symptomatic relief of nasal and non-nasal allergy symptoms such as sneezing, runny nose, itchy and watery eyes, and skin itching or hives.
- Oral solution form: Offers an alternative to tablets for patients who have difficulty swallowing pills, such as children or elderly individuals.
- Non-sedating: Being a second-generation antihistamine, AERIUS has minimal penetration into the central nervous system, reducing drowsiness compared to first-generation antihistamines.
- Onset and duration: Begins working within 1 to 3 hours after administration with effects lasting up to 24 hours, allowing once-daily dosing.
Overall, AERIUS 0.5mg/ml oral solution is a convenient and effective option for managing allergy symptoms in a wide range of patients.
How to use AERIUS 0.5mg/ml
Proper administration of AERIUS 0.5mg/ml oral solution is important to ensure effectiveness and safety:
- Dosage measurement: Use the provided measuring device or a calibrated oral syringe to ensure accurate dosing.
- Typical dosing: Follow your healthcare provider’s recommendations. For adults and children aged 12 years and above, the usual dose is 5 ml (2.5 mg) once daily.
- Pediatric dosing: For children aged 6 to 11 years, typically 2.5 ml (1.25 mg) once daily; younger children dosing depends on physician advice.
- Administration: The solution can be taken with or without food.
- Timing: Preferably take at the same time each day to maintain consistent blood levels.
- Missed dose: If a dose is missed, take it as soon as remembered unless it is near the time of the next dose. Do not double doses to compensate.
- Duration of treatment: Use for the duration prescribed; do not stop treatment abruptly unless advised by a healthcare provider.
- Consultation: Inform your healthcare provider about all medications and health conditions before starting.
Correct use helps achieve optimal symptom control with minimal risk of side effects.
Mode of Action AERIUS 0.5mg/ml
AERIUS contains desloratadine, which acts specifically on histamine H1 receptors to reduce allergic symptoms:
- Histamine antagonist: Desloratadine selectively blocks peripheral H1-receptors, preventing histamine from binding and triggering allergic reactions.
- Reduction of symptoms: By inhibiting histamine’s effects, it reduces typical allergic manifestations such as itching, sneezing, runny nose, and hives.
- Non-sedating profile: Limited penetration across the blood-brain barrier means it does not cause significant sedation or drowsiness, unlike first-generation antihistamines.
- Anti-inflammatory effects: Desloratadine also modulates release of other inflammatory mediators, providing additional relief beyond histamine blockade.
- Pharmacokinetics: After oral administration, desloratadine is rapidly absorbed, reaching peak plasma levels in about 3 hours, with a half-life of approximately 27 hours, supporting once-daily dosing.
Through these mechanisms, AERIUS efficiently manages allergic symptoms with a favorable safety profile.
AERIUS 0.5mg/ml Interactions AERIUS 0.5mg/ml
Although AERIUS generally has a low potential for drug interactions, certain medications and substances can affect its efficacy or safety:
- CYP3A4 and CYP2D6 inhibitors: Desloratadine is metabolized by these liver enzymes. Potent inhibitors such as ketoconazole, erythromycin, or cimetidine may increase desloratadine levels slightly, though clinically significant interactions are rare.
- Other antihistamines: Concurrent use with other antihistamines is generally not recommended, as it may increase risk of side effects.
- Alcohol and CNS depressants: Though desloratadine is non-sedating, combining it with alcohol or sedatives might increase drowsiness in sensitive individuals.
- Ritonavir and other antiviral agents: May increase desloratadine plasma concentrations, necessitating caution or dose adjustment.
- Monoamine oxidase inhibitors (MAOIs): No significant interactions expected, but caution advised with other drugs affecting the central nervous system.
- Always consult your healthcare provider: Disclose all medications, supplements, or herbal products you are taking to avoid potential interactions.
Overall, AERIUS is considered safe with minimal interaction risks when used as directed.
Dosage of AERIUS 0.5mg/ml
Correct dosing of AERIUS oral solution depends on the patient's age and medical condition:
- Adults and adolescents (≥12 years): 5 ml (2.5 mg desloratadine) once daily is the standard dose.
- Children aged 6 to 11 years: Typically 2.5 ml (1.25 mg) once daily.
- Children under 6 years: Safety and efficacy not fully established; use only under medical supervision.
- Renal or hepatic impairment: Usually no dose adjustment needed, but caution advised in severe cases.
- Elderly patients: No special dose adjustment generally required.
- Duration: Use for the period recommended by your healthcare provider, usually during allergy seasons or chronic symptom management.
- Administration tips: Use the supplied measuring device for accurate dosing; do not exceed recommended doses.
Adhering to these dosage guidelines helps ensure safe and effective treatment of allergic symptoms.
Possible side effects of AERIUS 0.5mg/ml
Although AERIUS 0.5mg/ml is well tolerated, some patients may experience side effects. Most are mild and transient:
- Common side effects:
- Headache
- Drowsiness or fatigue (less common than first-generation antihistamines)
- Dry mouth
- Nausea
- Pharyngitis (sore throat)
- Uncommon side effects:
- Dizziness
- Abdominal pain
- Increased appetite or weight changes (rare)
- Rare but serious reactions:
- Allergic reactions such as rash, itching, swelling, or difficulty breathing
- Palpitations or irregular heartbeat
- Severe headache or neurological symptoms
- When to seek medical advice: If side effects are severe, persistent, or suggest an allergic reaction, stop taking the medication and consult a healthcare professional immediately.
Monitoring and reporting side effects contributes to safe ongoing use of AERIUS.
AERIUS 0.5mg/ml Contraindications AERIUS 0.5mg/ml
AERIUS 0.5mg/ml should not be used in the following circumstances to avoid harm:
- Hypersensitivity: Known allergy to desloratadine, loratadine, or any excipients in the formulation.
- Severe renal or hepatic impairment: Use with caution or avoid as pharmacokinetics may be altered.
- Children under 6 years: Safety and efficacy not fully established for this age group with this formulation.
- Pregnancy and breastfeeding: Use only if clearly necessary and after consulting a healthcare provider.
- Concomitant use with other H1-antihistamines: May increase risk of adverse effects.
Patients should disclose all medical conditions and medications to their healthcare provider before starting treatment with AERIUS to ensure safe use.
Storage of AERIUS 0.5mg/ml
Proper storage of AERIUS oral solution maintains its quality and effectiveness:
- Temperature: Store at room temperature, ideally between 15°C and 30°C (59°F to 86°F).
- Light protection: Keep the bottle in its original packaging to protect from light exposure.
- Humidity: Store in a dry place away from moisture, avoiding bathrooms or damp environments.
- Cap tightly: Ensure the bottle cap is securely closed after each use to prevent contamination or evaporation.
- Keep out of reach of children: Store safely to prevent accidental ingestion.
- Do not use after expiration date: Check the label for expiry and dispose of properly if expired.
- Disposal: Follow local regulations or pharmacy guidelines for safe disposal of unused or expired medication.
Adhering to storage instructions helps preserve the medication’s safety and efficacy for the entire treatment duration.
AERIUS 0.5mg/ml features an exceptional active ingredient renowned for its potent effects, comprising Desloratadine. This powerful formulation provides a superior solution for addressing diverse health concerns. With 0.5mg/ml concentration and an easily manageable Solution (Oral), it remains a preferred option for countless individuals seeking effective treatment.
Introduction
All you need to know about AERIUS 0.5mg/ml .
Welcome to Dwaey, specifically on AERIUS 0.5mg/ml page.
This medicine contains an important and useful components, as it consists of Desloratadine.
AERIUS 0.5mg/ml is available in the market in concentration 0.5mg/ml and in the form of Solution (Oral).
MERCK SHARP & DOHME B.V is the producer of AERIUS 0.5mg/ml and it is imported from NETHERLANDS,
The most popular alternatives of AERIUS 0.5mg/ml are listed downward .
-
Active Substance
-
Size
-
Indications
-
Type
-
Company
Frequently Asked Questions
AERIUS 0.5mg/ml should be stored according to the instructions provided by MERCK SHARP & DOHME B.V.
In general, it is recommended to store AERIUS 0.5mg/ml in a cool, dry place, away from direct sunlight
and out of the reach of children.
The duration of treatment with AERIUS 0.5mg/ml may vary depending on the condition being treated
and the guidance of your healthcare provider. It is important to follow the prescribed treatment
plan and continue taking AERIUS 0.5mg/ml for the recommended duration, even if your symptoms improve.
If you have any concerns or questions about the duration of treatment, consult your healthcare provider.
It is important to check with your healthcare provider or read the medication label for specific
instructions regarding alcohol consumption while taking AERIUS 0.5mg/ml. Some medications, including
AERIUS 0.5mg/ml, may have interactions with alcohol that can reduce effectiveness, increase side
effects, or pose other risks to your health. It is best to follow the guidance provided by your
healthcare professional.
If you miss a dose of AERIUS 0.5mg/ml, take it as soon as you remember. However, if it is close
to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing
schedule. Do not take a double dose to make up for a missed one unless advised by your healthcare provider.
No, do not stop taking AERIUS 0.5mg/ml without consulting your healthcare provider, even if your
symptoms improve. It is important to complete the full course of treatment as prescribed. Stopping
the medication prematurely may lead to a relapse or incomplete resolution of the condition. If you
have concerns about the duration of treatment, consult your healthcare provider for guidance.
It is important to consult your healthcare provider before taking AERIUS 0.5mg/ml if you are
pregnant or breastfeeding. They will be able to assess the potential risks and benefits based on your
specific situation. Please note that the safety and suitability of AERIUS 0.5mg/ml during pregnancy
or breastfeeding may depend on the active substance [Active Substance], concentration 0.5mg/ml,
and the specific recommendations of MERCK SHARP & DOHME B.V.
The effects of AERIUS 0.5mg/ml on your ability to drive or operate machinery can vary depending on
the active substance [Active Substance], concentration 0.5mg/ml, and individual factors.
Some medications may cause drowsiness, dizziness, or other side effects that can impair your judgment
or coordination. It is important to read the medication label or consult your healthcare provider to
understand any potential effects on your ability to perform tasks that require alertness.
The instructions for taking AERIUS 0.5mg/ml with or without food may vary depending on the medication
and the recommendations of MERCK SHARP & DOHME B.V. Some medications may be more effective when taken with
food to enhance absorption or reduce stomach irritation, while others may need to be taken on an empty
stomach for optimal absorption. Read the medication label or consult your healthcare provider for specific instructions.
The use of AERIUS 0.5mg/ml in children or elderly individuals may depend on various factors, including
the specific medication, type Solution (Oral), and the recommendations of MERCK SHARP & DOHME B.V. Some
medications may have specific dosing instructions or precautions for these age groups. Consult your
healthcare provider or read the medication label for information regarding the safe and appropriate use
of AERIUS 0.5mg/ml in children or elderly individuals.
Dwaey
All medical information published on the Dwaey website aims to increase medical awareness and health education among users. However, it is not a substitute for professional medical advice. Always consult with a specialist doctor. We strongly advise against using any information or medicine found on the site without referring to your healthcare provider.
Related Products
0 Comments