What is ADTRALZA 150 mg
ADTRALZA is a prescription biologic medication containing the active substance tralokinumab, a fully human monoclonal antibody. It is designed for the treatment of moderate-to-severe atopic dermatitis (eczema) in adults who are candidates for systemic therapy.
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Key Features:
Active Ingredient: Tralokinumab
Formulation: 150 mg/mL solution in pre-filled syringes
Administration: Subcutaneous injection
Packaging: Available in packs of 4 (2 packs of 2) pre-filled syringes
Indication: Treatment of moderate-to-severe atopic dermatitis in adults
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Tralokinumab works by targeting and neutralizing interleukin-13 (IL-13), a cytokine involved in the inflammatory processes of atopic dermatitis. By inhibiting IL-13, ADTRALZA helps reduce skin inflammation, itching, and other symptoms associated with eczema .
How to use ADTRALZA 150 mg
ADTRALZA is administered via subcutaneous injection. Patients may self-inject after proper training by a healthcare professional.
Administration Guidelines:
Initial Dose: 600 mg, given as four 150 mg injections at different sites on the same day.
Maintenance Dose: 300 mg, administered as two 150 mg injections every other week.
Injection Sites: Thighs, abdomen (avoiding a 5 cm area around the navel), or upper arms (if administered by someone else).
Preparation:
Allow the syringe to reach room temperature (approximately 30 minutes) before injection.
Do not shake the syringe.
Inspect the solution for clarity; it should be clear to opalescent and colorless to pale yellow.
Missed Dose: If a dose is missed, administer it as soon as possible and resume the regular dosing schedule .
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Always follow the specific instructions provided by your healthcare provider regarding injection technique and site rotation.
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Mode of Action ADTRALZA 150 mg
ADTRALZA contains tralokinumab, which is a fully human IgG4 monoclonal antibody that specifically binds to interleukin-13 (IL-13).
Mechanism Details:
Target: IL-13, a cytokine involved in the inflammatory response in atopic dermatitis.
Action: By binding to IL-13, tralokinumab prevents its interaction with IL-13 receptors, thereby inhibiting the downstream inflammatory signaling pathways.
Result: Reduction in skin inflammation, improvement in skin barrier function, and alleviation of symptoms such as itching and redness .
This targeted approach helps in managing the chronic inflammation characteristic of atopic dermatitis.
ADTRALZA 150 mg Interactions ADTRALZA 150 mg
While tralokinumab is not metabolized by liver enzymes and has a low potential for drug-drug interactions, certain considerations should be noted:
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Drug Interactions:
Live Vaccines: Avoid concurrent administration with live or live-attenuated vaccines due to potential risk of infection. Complete necessary vaccinations before initiating therapy .
Non-Live Vaccines: Can be administered safely; studies have shown no adverse interactions .
Immunosuppressants: Caution is advised when used concomitantly with other immunosuppressive agents; monitor for increased risk of infections.
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Always inform your healthcare provider about all medications and supplements you are taking to assess potential interactions.
Dosage of ADTRALZA 150 mg
The dosing regimen for ADTRALZA is as follows:
Recommended Dosage:
Initial Dose: 600 mg, administered as four 150 mg subcutaneous injections on the same day.
Maintenance Dose: 300 mg, given as two 150 mg injections every other week.
Alternative Maintenance: For patients achieving clear or almost clear skin after 16 weeks, a maintenance dose of 300 mg every four weeks may be considered .
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Dosage adjustments should be made based on clinical response and under the guidance of a healthcare professional.
Possible side effects of ADTRALZA 150 mg
Like all medications, ADTRALZA may cause side effects. Not all patients will experience these, and many side effects are mild and manageable.
Common Side Effects:
Upper respiratory tract infections (e.g., sore throat, nasal congestion)
Injection site reactions (redness, pain, swelling)
Conjunctivitis (eye redness and discomfort)
Headache
Elevated eosinophil levels in blood tests
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Less Common Side Effects:
Fatigue
Fever
Nausea
Hypersensitivity reactions (e.g., rash, hives)
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If you experience any severe or persistent side effects, contact your healthcare provider promptly.
ADTRALZA 150 mg Contraindications ADTRALZA 150 mg
ADTRALZA should not be used in certain situations:
Contraindications:
Hypersensitivity: Known allergy to tralokinumab or any of the excipients in the formulation.
Active Infections: Should not be initiated in patients with active or chronic infections until the infection is resolved.
Pregnancy and Lactation: Use only if the potential benefit justifies the potential risk to the fetus or infant. Limited data are available .
Pediatric Use: Safety and efficacy have not been established in children under 12 years of age .
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Discuss your medical history thoroughly with your healthcare provider before starting ADTRALZA.
Storage of ADTRALZA 150 mg
Proper storage of ADTRALZA is essential to maintain its efficacy:
Storage Instructions:
Refrigeration: Store in a refrigerator at 2°C to 8°C (36°F to 46°F).
Room Temperature: If necessary, the pre-filled syringes may be kept at room temperature (up to 25°C or 77°F) for a maximum of 14 days. Do not return to the refrigerator once stored at room temperature .
Protection from Light: Keep the syringes in the original carton to protect from light.
Do Not Freeze: Avoid freezing the medication.
Disposal: Dispose of any unused or expired medication according to local regulations.
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Always check the expiration date and consult your pharmacist or healthcare provider if you have any questions about storage.
ADTRALZA 150 mg features an exceptional active ingredient renowned for its potent effects, comprising Tralokinumab. This powerful formulation provides a superior solution for addressing diverse health concerns. With 150mg / ml concentration and an easily manageable Injection Solution for, it remains a preferred option for countless individuals seeking effective treatment.
Introduction
All you need to know about ADTRALZA 150 mg .
Welcome to Dwaey, specifically on ADTRALZA 150 mg page.
This medicine contains an important and useful components, as it consists of Tralokinumab.
ADTRALZA 150 mg is available in the market in concentration 150mg / ml and in the form of Injection Solution for.
LEO PHARMA A/S is the producer of ADTRALZA 150 mg and it is imported from DENMARK,
The most popular alternatives of ADTRALZA 150 mg are listed downward .
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Active Substance
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Size
4 (2 packs of 2) pre-filled syringes
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Indications
- No indications available.
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Type
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Company
Frequently Asked Questions
ADTRALZA 150 mg should be stored according to the instructions provided by LEO PHARMA A/S .
In general, it is recommended to store ADTRALZA 150 mg in a cool, dry place, away from direct sunlight
and out of the reach of children.
The duration of treatment with ADTRALZA 150 mg may vary depending on the condition being treated
and the guidance of your healthcare provider. It is important to follow the prescribed treatment
plan and continue taking ADTRALZA 150 mg for the recommended duration, even if your symptoms improve.
If you have any concerns or questions about the duration of treatment, consult your healthcare provider.
It is important to check with your healthcare provider or read the medication label for specific
instructions regarding alcohol consumption while taking ADTRALZA 150 mg . Some medications, including
ADTRALZA 150 mg , may have interactions with alcohol that can reduce effectiveness, increase side
effects, or pose other risks to your health. It is best to follow the guidance provided by your
healthcare professional.
If you miss a dose of ADTRALZA 150 mg , take it as soon as you remember. However, if it is close
to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing
schedule. Do not take a double dose to make up for a missed one unless advised by your healthcare provider.
No, do not stop taking ADTRALZA 150 mg without consulting your healthcare provider, even if your
symptoms improve. It is important to complete the full course of treatment as prescribed. Stopping
the medication prematurely may lead to a relapse or incomplete resolution of the condition. If you
have concerns about the duration of treatment, consult your healthcare provider for guidance.
It is important to consult your healthcare provider before taking ADTRALZA 150 mg if you are
pregnant or breastfeeding. They will be able to assess the potential risks and benefits based on your
specific situation. Please note that the safety and suitability of ADTRALZA 150 mg during pregnancy
or breastfeeding may depend on the active substance [Active Substance], concentration 150mg / ml,
and the specific recommendations of LEO PHARMA A/S .
The effects of ADTRALZA 150 mg on your ability to drive or operate machinery can vary depending on
the active substance [Active Substance], concentration 150mg / ml, and individual factors.
Some medications may cause drowsiness, dizziness, or other side effects that can impair your judgment
or coordination. It is important to read the medication label or consult your healthcare provider to
understand any potential effects on your ability to perform tasks that require alertness.
The instructions for taking ADTRALZA 150 mg with or without food may vary depending on the medication
and the recommendations of LEO PHARMA A/S . Some medications may be more effective when taken with
food to enhance absorption or reduce stomach irritation, while others may need to be taken on an empty
stomach for optimal absorption. Read the medication label or consult your healthcare provider for specific instructions.
The use of ADTRALZA 150 mg in children or elderly individuals may depend on various factors, including
the specific medication, type Injection Solution for, and the recommendations of LEO PHARMA A/S . Some
medications may have specific dosing instructions or precautions for these age groups. Consult your
healthcare provider or read the medication label for information regarding the safe and appropriate use
of ADTRALZA 150 mg in children or elderly individuals.
Dwaey
All medical information published on the Dwaey website aims to increase medical awareness and health education among users. However, it is not a substitute for professional medical advice. Always consult with a specialist doctor. We strongly advise against using any information or medicine found on the site without referring to your healthcare provider.
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