LIORESAL 25mg Tablets

What is LIORESAL 25mg

LIORESAL 25 mg contains Baclofen, a muscle relaxant used primarily to treat muscle spasticity caused by neurological disorders such as multiple sclerosis, spinal cord injuries, or other conditions affecting muscle control. Baclofen acts centrally on the spinal cord to reduce muscle stiffness, spasms, and pain, helping improve mobility and quality of life.

• Therapeutic class: Muscle relaxant and antispastic agent
• Indications: Relief of muscle spasticity in neurological conditions
• Mechanism: Acts on GABA_B receptors to inhibit nerve signals causing muscle contraction
• Usage: Prescription-only, under strict medical supervision

How to use LIORESAL 25mg

Use LIORESAL exactly as prescribed by your healthcare provider. Do not alter your dose or stop treatment without consulting your doctor.

• Route: Oral
• Dosage: Usually given in divided doses throughout the day
• Swallow tablets: With water, with or without food
• Important: Avoid sudden discontinuation to prevent withdrawal symptoms
• Monitoring: Regular follow-up for dose adjustment and side effect monitoring

Mode of Action LIORESAL 25mg

Baclofen acts as an agonist at GABA_B receptors in the spinal cord. This action inhibits excitatory neurotransmitter release, leading to decreased muscle tone and spasticity.

• Target: GABA_B receptors
• Effect: Reduced nerve excitability and muscle spasm
• Outcome: Improved muscle relaxation and mobility

LIORESAL 25mg Interactions LIORESAL 25mg

Interactions with other CNS depressants and medications may enhance sedative effects or muscle relaxation.

• Alcohol: May increase sedation and risk of respiratory depression
• Benzodiazepines, opioids: Additive CNS depression
• Antihypertensives: May cause additive hypotensive effects
• Other muscle relaxants: Risk of increased muscle weakness

Dosage of LIORESAL 25mg

The dosage should be individualized according to patient response and condition severity.

• Adults: Dose usually starts at lower amounts (5 mg) and titrated up
• Maintenance dose: Commonly 40-80 mg daily in divided doses; 25 mg tablets can be used for dose adjustment
• Special populations: Dose adjustment may be necessary for elderly or patients with renal impairment

Possible side effects of LIORESAL 25mg

• Drowsiness, dizziness, weakness
• Fatigue, headache
• Nausea, constipation
• Rare: Confusion, hallucinations, muscle weakness
• Serious: Seizures, allergic reactions (seek immediate medical attention)

LIORESAL 25mg Contraindications LIORESAL 25mg

• Hypersensitivity to Baclofen
• Severe renal impairment (use with caution)
• History of epilepsy (caution advised)
• Pregnancy and breastfeeding only if benefits outweigh risks

Storage of LIORESAL 25mg

• Store at room temperature (20°C - 25°C)
• Keep away from moisture, heat, and light
• Keep out of reach of children
• Do not use beyond expiration date