LIOCAINE 2% Gel

What is LIOCAINE 2%

LIOCAINE 2% is a topical anesthetic gel that contains Lidocaine Hydrochloride as its active ingredient. It is used to relieve localized pain or discomfort in various parts of the body. Lidocaine is an amide-type local anesthetic that works by blocking nerve signals in the skin and mucous membranes.

• Therapeutic Category: Local anesthetic
• Indications: Used for temporary relief of pain from minor burns, insect bites, skin irritations, hemorrhoids, and minor surgical or dental procedures
• Formulation: Clear or translucent gel for external use only
• Concentration: 2% Lidocaine HCl (20 mg/g)

LIOCAINE 2% is available over the counter or may be prescribed, depending on the condition being treated. It should only be used as directed by a healthcare provider, particularly in sensitive areas or for prolonged use.

How to use LIOCAINE 2%

Before using LIOCAINE 2%, carefully read the instructions and follow the application guidelines provided by your healthcare provider or the product leaflet.

• Application Area: External use on skin or mucous membranes (e.g., gums, genital area)
• Dosage: Apply a thin layer (typically pea-sized) to the affected area 2 to 3 times daily as needed
• Hands: Wash hands before and after applying the gel
• Avoid: Contact with eyes, nose, mouth (unless specifically directed), or broken skin

Do not cover the area with a bandage or dressing unless instructed by a doctor, as this can increase absorption and potential toxicity.

Mode of Action LIOCAINE 2%

Lidocaine works by inhibiting sodium ion channels on the neuronal cell membrane. By doing so, it prevents the initiation and transmission of nerve impulses that convey sensations such as pain, itching, or burning.

• Target: Voltage-gated sodium channels in peripheral nerves
• Onset of Action: Usually within 2–5 minutes of application
• Duration of Action: Effects typically last 30 minutes to 1 hour

Lidocaine provides localized relief without affecting consciousness or central nervous system activity when used topically.

LIOCAINE 2% Interactions LIOCAINE 2%

Although topical lidocaine generally has minimal systemic absorption, caution is warranted if used over large areas or for prolonged periods.

• Antiarrhythmics (e.g., mexiletine, amiodarone): May enhance systemic effects of lidocaine
• Other topical anesthetics: Additive effect may increase risk of toxicity
• Beta-blockers or cimetidine: May increase lidocaine blood levels if systemically absorbed

Always inform your healthcare provider about all medications you’re taking, especially if you are using multiple topical products.

Dosage of LIOCAINE 2%

Dosage depends on the area to be treated and the condition being managed. Never exceed the recommended amount or frequency.

• Adults: Apply a thin layer (approximately 1–2 grams) up to 3–4 times daily
• Children: Use only under medical supervision; dosage should be significantly reduced
• Maximum Dose: Do not exceed 17–20 grams of gel in a 24-hour period unless instructed
• Special Populations: Adjust use in elderly or patients with hepatic dysfunction

Overuse can result in systemic toxicity—seek medical help if signs such as dizziness, irregular heartbeat, or confusion appear.

Possible side effects of LIOCAINE 2%

Most patients tolerate LIOCAINE well when used correctly, but side effects can occur, especially with prolonged use or overapplication.

• Common: Mild skin irritation, redness, or itching at the site of application
• Less Common: Numbness beyond the targeted area, rash, or stinging
• Rare but Serious: Seizures, slow heartbeat, difficulty breathing (in case of systemic absorption or overdose)

Discontinue use and consult your doctor if you experience severe reactions or symptoms persist.

LIOCAINE 2% Contraindications LIOCAINE 2%

• Known hypersensitivity to lidocaine or other local anesthetics of the amide type
• Severe hepatic impairment
• Broken or severely damaged skin in the application area
• Patients with known methemoglobinemia

Use cautiously in elderly, infants, and individuals with heart or liver problems.

Storage of LIOCAINE 2%

• Store below 25°C (77°F) in a dry place
• Do not freeze or expose to direct sunlight
• Keep tightly closed when not in use
• Keep out of reach of children

Do not use the gel after the expiration date. Discard safely as per local pharmaceutical disposal regulations.