LEZODEX 2.5mg Tablets/Film-coated

What is LEZODEX 2.5mg

LEZODEX 2.5 mg is a prescription medication in the form of film-coated tablets, containing the active ingredient Letrozole, which is a non-steroidal aromatase inhibitor. Letrozole is primarily used in the treatment of hormone receptor-positive breast cancer in postmenopausal women. It works by inhibiting the enzyme aromatase, which is responsible for the production of estrogen. By reducing estrogen levels, Letrozole helps to slow down or stop the growth of estrogen-dependent breast cancer cells.

• Active Ingredient: Letrozole 2.5 mg per tablet
• Therapeutic Class: Aromatase inhibitor
• Indication: Treatment of hormone receptor-positive breast cancer in postmenopausal women
• Form: Film-coated tablet
• Size: 30 tablets (10 tablets x 3 blister packs)

Letrozole is not used for premenopausal women or those who are pregnant or breastfeeding due to potential risks. It is an essential medication for managing certain types of breast cancer in postmenopausal women.

How to use LEZODEX 2.5mg

LEZODEX 2.5 mg is typically prescribed once daily as part of a comprehensive breast cancer treatment regimen. The dosage should be followed as prescribed by a healthcare provider.

• Administration: Oral use only, with or without food
• Recommended Dose: 2.5 mg once daily
• Consistency: Take at the same time each day to aid in remembering
• Duration: Typically used for a minimum of 5 years, depending on the doctor's recommendation

If you miss a dose, take it as soon as possible unless it is close to the time for your next dose. Do not take two doses at once to make up for a missed dose.

Mode of Action LEZODEX 2.5mg

Letrozole works by inhibiting the enzyme aromatase, which converts androgens into estrogens. By blocking the production of estrogen, Letrozole reduces the levels of this hormone, which is responsible for the growth of certain types of breast cancer cells that are estrogen receptor-positive.

• Primary Mechanism: Inhibition of the aromatase enzyme
• Effect: Reduces estrogen levels, slowing down the growth of estrogen-dependent cancer cells
• Onset: Takes weeks to months for significant effect in breast cancer management
• Duration: Ongoing as part of long-term cancer management

By reducing estrogen, Letrozole effectively controls cancer progression in women whose tumors are fueled by estrogen.

LEZODEX 2.5mg Interactions LEZODEX 2.5mg

Several drug interactions may occur with Letrozole. It's important to inform your doctor about any medications, supplements, or herbal products you are taking.

• Estrogen Therapy: Should not be used concurrently as it may reduce the effectiveness of Letrozole
• Tamoxifen: May interfere with Letrozole's action, as it is an estrogen receptor antagonist
• Strong CYP3A4 Inhibitors: May increase Letrozole levels, requiring dose adjustments
• Other Anticancer Drugs: Check with your healthcare provider for potential interactions

Always consult with your healthcare provider before starting or discontinuing any medications.

Dosage of LEZODEX 2.5mg

The typical dosage of LEZODEX is 2.5 mg once daily. However, your doctor may adjust the dose depending on your specific condition, response to treatment, and any side effects experienced.

• Standard Dose: 2.5 mg once daily
• Duration: Long-term use, usually for 5 years, depending on your treatment plan
• Missed Dose: Take as soon as you remember, unless it’s almost time for the next dose
• Overdose: In case of overdose, seek immediate medical attention

Always follow your doctor’s guidance on how to take this medication for the best results.

Possible side effects of LEZODEX 2.5mg

The side effects of LEZODEX are generally mild, but some may be serious. Be sure to report any persistent or troubling symptoms to your healthcare provider.

• Common: Hot flashes, joint pain, fatigue, nausea, and headache
• Less Common: Osteoporosis (bone thinning), depression, hair thinning
• Serious: Severe allergic reactions, liver problems (yellowing of the skin or eyes), and heart problems

Contact your doctor if you experience any unusual or severe side effects.

LEZODEX 2.5mg Contraindications LEZODEX 2.5mg

• Hypersensitivity: Do not use if allergic to Letrozole or any of its components
• Pregnancy: Contraindicated during pregnancy due to potential harm to the fetus
• Breastfeeding: Contraindicated as it may pass into breast milk
• Pre-menopausal Women: Not recommended as it is ineffective in premenopausal women

Consult your doctor to ensure this medication is appropriate for your specific medical history and condition.

Storage of LEZODEX 2.5mg

• Store in a cool, dry place at room temperature (15°C–30°C or 59°F–86°F)
• Keep away from moisture, heat, and light
• Keep the medication out of reach of children
• Do not use past the expiration date printed on the package

Dispose of any unused medication properly, following local disposal guidelines.