LEZAL 0.5 mg/mL Oral Solution

What is LEZAL 0.5 mg/mL

LEZAL 0.5 mg/mL is an oral solution containing the active ingredient Sodium Cromoglycate, a mast cell stabilizer commonly used for the management of allergic disorders. It is typically prescribed to reduce or prevent symptoms associated with allergies, including food allergies, allergic rhinitis, and mastocytosis.

• Generic Name: Sodium Cromoglycate
• Strength: 0.5 mg/mL
• Form: Oral solution
• Indications: Chronic allergic conditions (e.g., food allergy, systemic mastocytosis, allergic rhinitis)

Sodium Cromoglycate does not provide immediate relief of allergic symptoms but is used for long-term management and prevention by inhibiting the release of inflammatory mediators from mast cells.

How to use LEZAL 0.5 mg/mL

LEZAL should be taken as prescribed by a healthcare professional. It is typically used regularly for ongoing allergic conditions, not on an “as-needed” basis.

• Route: Oral (by mouth)
• Administration: Measure the dose accurately using a dosing cup or syringe
• Frequency: Usually taken 3–4 times daily before meals
• Consistency: Continued use is necessary for effective prevention of allergic symptoms

It is important to follow the full prescribed regimen even if symptoms improve, as abrupt discontinuation may lead to recurrence of allergy symptoms.

Mode of Action LEZAL 0.5 mg/mL

Sodium Cromoglycate acts by stabilizing mast cells, thereby preventing the release of histamine and other inflammatory mediators involved in allergic reactions.

• Primary Mechanism: Inhibits degranulation of sensitized mast cells
• Effect: Prevents release of histamine, leukotrienes, and other mediators
• Onset: Therapeutic effect typically takes days to weeks with consistent use

This preventative approach helps reduce the severity and frequency of allergic reactions over time.

LEZAL 0.5 mg/mL Interactions LEZAL 0.5 mg/mL

LEZAL generally has a low interaction profile, but caution is always advised when combining with other medications.

• Antihistamines: May be used concurrently for added symptom control
• Oral Corticosteroids: No direct interaction, but dosage adjustments may be needed
• Other Anti-allergics: Compatible but should be used under medical supervision
• Food: Should be taken on an empty stomach or 15–30 minutes before meals

Always inform your doctor about all medications or supplements you are using to avoid unwanted interactions.

Dosage of LEZAL 0.5 mg/mL

Dosage should be tailored to the individual based on age, weight, and clinical condition.

• Children: 100–200 mg (approx. 5–10 mL) 3–4 times daily before meals
• Adults: Usually 200 mg (10 mL) 4 times a day before meals and at bedtime
• Adjustment: May be modified based on response and tolerability
• Missed Dose: If missed, take as soon as possible unless it's almost time for the next dose

Do not exceed the prescribed dose, and never double a dose to make up for a missed one.

Possible side effects of LEZAL 0.5 mg/mL

LEZAL is generally well tolerated. Most side effects are mild and transient.

• Common: Headache, nausea, stomach discomfort, and diarrhea
• Rare: Skin rash, joint pain, or mild dizziness
• Serious (rare): Anaphylactic reactions or severe gastrointestinal issues

If any serious symptoms or allergic reactions occur (e.g., swelling of face or throat, difficulty breathing), seek immediate medical attention.

LEZAL 0.5 mg/mL Contraindications LEZAL 0.5 mg/mL

• Hypersensitivity to Sodium Cromoglycate or any component of the formulation
• Acute asthma attacks (not intended for immediate symptom relief)

Caution should be used in individuals with known liver or kidney impairments; consult your doctor before use.

Storage of LEZAL 0.5 mg/mL

• Store at 15°C–25°C (59°F–77°F)
• Protect from light and moisture
• Keep the bottle tightly closed when not in use
• Keep out of reach of children
• Do not use after the expiration date

Discard any unused portion 30 days after opening unless otherwise instructed.