LEXTA 20mg Tablets/Film-coated

What is LEXTA 20mg

LEXTA 20 mg is a prescription medication formulated with the active ingredient Vardenafil, a phosphodiesterase type 5 (PDE5) inhibitor. It is primarily used to treat erectile dysfunction (ED) in adult men, enhancing the ability to achieve and maintain an erection sufficient for satisfactory sexual activity.

• Form: Tablets / Film-coated
• Strength: 20 mg of Vardenafil
• Packaging: Supplied in 4-tablet blister packs
• Therapeutic Class: Erectile Dysfunction Treatment
• Onset of Action: Typically within 30 to 60 minutes
• Duration of Action: Approximately 4 to 5 hours

This medication enhances blood flow to the penile tissue by relaxing blood vessels, but sexual stimulation is required for it to be effective. LEXTA is not a cure for ED, nor does it increase sexual desire.

It is important to consult a healthcare professional before starting LEXTA, especially for individuals with pre-existing cardiovascular conditions or those taking medications that may interact with Vardenafil.

How to use LEXTA 20mg

Take LEXTA 20 mg exactly as prescribed by your doctor. It is usually taken as needed, approximately 25 to 60 minutes before sexual activity.

• Dosage Form: Oral film-coated tablet
• Timing: Take 25–60 minutes before anticipated sexual activity
• Food Consideration: May be taken with or without food; however, high-fat meals may delay onset of action
• Max Frequency: No more than once per day

Swallow the tablet whole with a glass of water. Sexual stimulation is necessary for the medication to work.

Mode of Action LEXTA 20mg

Vardenafil works by inhibiting the enzyme PDE5, which is responsible for the degradation of cGMP (cyclic guanosine monophosphate). During sexual stimulation, nitric oxide is released, which promotes cGMP production. This leads to the relaxation of smooth muscle cells and dilation of blood vessels in the penis.

• Mechanism: Inhibits PDE5 → increases cGMP → enhances blood flow
• Effect: Promotes erection in response to sexual arousal
• Onset of Action: Within 25–60 minutes
• Duration: Effects may last up to 4–5 hours

LEXTA enhances the natural erectile response, but does not cause an erection in the absence of stimulation.

LEXTA 20mg Interactions LEXTA 20mg

Vardenafil can interact with several medications and substances. Always inform your doctor of all drugs and supplements you are taking.

• Nitrates: Contraindicated; can lead to life-threatening hypotension
• Alpha-blockers: Increased risk of low blood pressure
• Antifungals (e.g. ketoconazole): May raise vardenafil levels in blood
• HIV protease inhibitors: Strong inhibitors of CYP3A4 may increase drug exposure
• Grapefruit juice: Avoid; interferes with metabolism and increases side effect risk

Combining with other erectile dysfunction treatments is not recommended unless advised by a healthcare provider.

Dosage of LEXTA 20mg

The typical starting dose of Vardenafil is 10 mg, but LEXTA 20 mg may be prescribed in patients who require a stronger effect and tolerate the medication well.

• Starting Dose: 10 mg (adjusted based on efficacy and tolerability)
• Maximum Dose: 20 mg in a 24-hour period
• Elderly Patients: May require dose adjustment
• Hepatic or Renal Impairment: Dose reduction or avoidance may be necessary

Only take the prescribed dose. Overuse increases the risk of adverse effects without added benefit.

Possible side effects of LEXTA 20mg

Most side effects are mild and temporary. However, serious adverse reactions may occur, particularly in patients with underlying health issues.

• Common: Headache, facial flushing, nasal congestion, dizziness
• Gastrointestinal: Upset stomach or indigestion
• Visual: Slight blue tint to vision or sensitivity to light
• Serious: Chest pain, priapism (prolonged erection), sudden hearing or vision loss

Seek immediate medical attention for symptoms such as chest pain, severe dizziness, or an erection lasting more than 4 hours.

LEXTA 20mg Contraindications LEXTA 20mg

• Hypersensitivity to Vardenafil or any excipient in the formulation
• Concurrent use of nitrates or nitric oxide donors
• Severe cardiovascular disorders (e.g. recent stroke or heart attack)
• Severe liver impairment
• Retinitis pigmentosa (a rare genetic eye disease)

Patients with high-risk cardiac conditions should be carefully evaluated before receiving this medication.

Storage of LEXTA 20mg

• Store at room temperature: 15°C–30°C (59°F–86°F)
• Protect from light and moisture
• Keep in original blister until use
• Keep out of the reach of children

Do not use LEXTA after the expiry date mentioned on the packaging. Safely dispose of unused medication.