LEXIN 250mg Capsules (Hard Gelatin)

What is LEXIN 250mg

LEXIN 250 mg is an oral antibiotic medication that contains the active ingredient Cefalexin Monohydrate, a first-generation cephalosporin. It is used to treat various bacterial infections affecting the respiratory tract, skin, urinary tract, and other soft tissues. Cefalexin is known for its broad-spectrum activity against gram-positive and some gram-negative bacteria.

LEXIN 250 mg comes in the form of hard gelatin capsules and is often prescribed for mild to moderate infections or for pediatric use when appropriate. This antibiotic acts by disrupting bacterial cell wall synthesis, leading to cell lysis and death.

• Generic Name: Cefalexin Monohydrate
• Brand Name: LEXIN
• Form: Hard Gelatin Capsules
• Strength: 250 mg
• Indications: Respiratory infections, skin infections, UTIs, otitis media, dental infections

How to use LEXIN 250mg

LEXIN 250 mg capsules should be taken by mouth as directed by your healthcare provider. The dosage and frequency depend on the severity and type of infection being treated.

• Administration: Swallow the capsule whole with a full glass of water
• Frequency: Usually every 6 or 8 hours (3–4 times daily)
• With or Without Food: Can be taken with food to minimize gastrointestinal discomfort
• Compliance: Complete the full course to prevent recurrence or resistance

Do not skip doses, and avoid stopping the medication early even if you feel better.

Mode of Action LEXIN 250mg

Cefalexin, the active compound in LEXIN 250 mg, exerts its antibacterial effect by binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall. This binding inhibits the final transpeptidation step in the synthesis of peptidoglycan, an essential component of the bacterial cell wall.

• Action: Inhibits bacterial cell wall synthesis
• Effect: Bactericidal – leads to cell death
• Spectrum: Primarily effective against Streptococcus, Staphylococcus, E. coli, and Klebsiella

Its action is limited to susceptible bacterial strains, and resistance may occur with inappropriate or prolonged use.

LEXIN 250mg Interactions LEXIN 250mg

While generally safe, LEXIN 250 mg can interact with other drugs, affecting efficacy or increasing the risk of side effects.

• Probenecid: Can elevate cefalexin levels by decreasing renal clearance
• Metformin: May alter glucose metabolism; monitor blood glucose
• Anticoagulants: Risk of enhanced anticoagulant effect (e.g., with warfarin)
• Live Vaccines: May interfere with the effectiveness of oral typhoid vaccine

Always consult your healthcare provider or pharmacist before combining cefalexin with other treatments.

Dosage of LEXIN 250mg

LEXIN 250 mg is generally used for mild to moderate infections or in patients requiring lower dosages such as children or the elderly. Dosage must be tailored to individual needs.

• Adults: 250–500 mg every 6 hours, depending on infection type
• Children: Dosing based on weight – typically 25–50 mg/kg/day in divided doses
• Renal Impairment: May require dose adjustments

Never self-adjust your dose; follow your physician’s instructions carefully.

Possible side effects of LEXIN 250mg

While most users tolerate LEXIN 250 mg well, some individuals may experience side effects, which range from mild to severe.

• Common: Diarrhea, nausea, stomach upset
• Allergic Reactions: Rash, itching, swelling, especially in those with penicillin allergies
• Rare: C. difficile-associated diarrhea, liver enzyme elevation
• Serious (Rare): Anaphylaxis, Stevens-Johnson syndrome

Seek immediate medical attention if severe allergic symptoms or persistent diarrhea occur.

LEXIN 250mg Contraindications LEXIN 250mg

LEXIN 250 mg should not be used in certain conditions or populations due to the risk of adverse reactions.

• Hypersensitivity: Known allergy to cefalexin or other cephalosporins
• Cross-Allergy: Use with caution in penicillin-allergic individuals
• Severe Renal Dysfunction: Use only under strict medical supervision

Discuss your full medical history with your doctor before starting the medication.

Storage of LEXIN 250mg

• Temperature: Store at or below 25°C (77°F)
• Humidity: Keep in a dry place away from moisture and sunlight
• Packaging: Keep in original blister until use
• Children: Store out of reach of children and pets

Do not use expired medication. Return unused capsules to a pharmacy for safe disposal.