LEXIN 1g Tablets

What is LEXIN 1g

LEXIN 1g is a prescription antibiotic medication that contains the active ingredient Cefalexin Monohydrate (also spelled *Cephalexin*). It belongs to the class of antibiotics known as first-generation cephalosporins and is primarily used to treat a wide range of bacterial infections. These include infections of the respiratory tract, urinary tract, skin, bones, joints, and certain dental infections.

Cefalexin works by interfering with the formation of the bacterial cell wall, leading to cell rupture and death. It is particularly effective against gram-positive bacteria and some gram-negative bacteria. The 1g strength is typically reserved for more severe infections or as part of a high-dose treatment regimen under medical supervision.

• Generic Name: Cefalexin Monohydrate
• Brand Name: LEXIN
• Form: Tablets
• Strength: 1g (1000 mg)
• Pharmacological Class: First-generation cephalosporin antibiotic
• Common Uses: Skin infections, tonsillitis, bronchitis, UTIs, bone infections

How to use LEXIN 1g

LEXIN 1g should be used exactly as directed by your healthcare provider. The tablets are taken orally and are typically administered 1–2 times daily, depending on the severity and type of infection.

• Route: Oral
• Administration: Swallow whole with water; do not crush or chew unless advised
• Timing: Take at evenly spaced intervals for consistent antibiotic levels
• With or Without Food: May be taken with food to reduce stomach upset
• Course Duration: Complete the full course even if symptoms improve early

Skipping doses or stopping early can result in antibiotic resistance or recurrence of infection.

Mode of Action LEXIN 1g

Cefalexin, the active component in LEXIN 1g, is a beta-lactam antibiotic that targets bacterial cell wall synthesis. It binds to penicillin-binding proteins (PBPs) inside the bacterial cell membrane, inhibiting the final transpeptidation step in peptidoglycan synthesis.

• Mechanism: Inhibits bacterial cell wall formation
• Bactericidal Action: Causes rupture and death of susceptible bacteria
• Spectrum: Effective against many gram-positive and some gram-negative organisms
• Onset of Action: Therapeutic effect typically observed within 1–2 days of treatment

Cefalexin is stable in the presence of gastric acid and is well-absorbed after oral administration.

LEXIN 1g Interactions LEXIN 1g

LEXIN 1g may interact with other medications, which could affect its efficacy or increase the risk of side effects.

• Probenecid: May increase cefalexin blood levels by decreasing renal excretion
• Oral Contraceptives: May reduce the effectiveness of hormonal birth control
• Metformin: Cefalexin may increase metformin levels; monitor blood sugar closely
• Anticoagulants (e.g., warfarin): May increase bleeding risk

Always inform your healthcare provider about all medications, supplements, or herbal products you are taking.

Dosage of LEXIN 1g

LEXIN 1g is typically prescribed for adults or adolescents with severe infections or those requiring higher dosing. Dosage depends on the type of infection and patient-specific factors such as renal function.

• Adults: 1g every 8–12 hours depending on the severity of the infection
• Renal Impairment: Dosage adjustment may be required; monitor kidney function
• Children: Not commonly used in 1g strength; lower strengths are preferred
• Duration: Typically 7–14 days based on infection type and clinical response

Do not self-adjust the dosage. Take exactly as prescribed by your healthcare provider.

Possible side effects of LEXIN 1g

Like all antibiotics, LEXIN 1g may cause side effects. Most are mild and temporary, but some can be serious and require medical attention.

• Common: Diarrhea, nausea, vomiting, abdominal pain
• Allergic Reactions: Rash, itching, hives, swelling of face or lips
• Severe: Anaphylaxis, Stevens-Johnson syndrome (rare)
• Gastrointestinal: Clostridioides difficile-associated diarrhea (C. diff)
• Hematologic: Rarely causes neutropenia or eosinophilia

Report any signs of allergic reaction or severe gastrointestinal symptoms immediately.

LEXIN 1g Contraindications LEXIN 1g

LEXIN 1g is contraindicated in certain individuals and should not be used under the following conditions:

• Known Allergy: Hypersensitivity to cefalexin, cephalosporins, or penicillins
• Severe Renal Disease: Caution is needed; may require alternative antibiotic
• History of Severe Allergic Reaction: Especially to beta-lactam antibiotics

Consult your doctor if you have a history of allergies, kidney disease, or gastrointestinal conditions.

Storage of LEXIN 1g

• Temperature: Store at room temperature below 25°C (77°F)
• Humidity: Keep in a dry place; avoid exposure to moisture
• Packaging: Store in the original blister until ready to use
• Child Safety: Keep out of reach of children and pets

Do not use after the expiry date printed on the packaging. Return any unused medication to your pharmacy for proper disposal.