LEVOKILZ 500mg Tablets/Film-coated

What is LEVOKILZ 500mg

LEVOKILZ 500mg is a high-strength, broad-spectrum antibiotic tablet containing the active substance Levofloxacin. It belongs to the fluoroquinolone class of antimicrobials and is designed to treat various bacterial infections effectively. LEVOKILZ is presented as a film-coated tablet in a 5’s blister pack, making it convenient for short-term therapies.

Key Information:

• Generic Name: Levofloxacin
• Form: Film-coated tablets
• Strength: 500mg
• Indications: Respiratory infections, urinary tract infections, sinusitis, skin infections, and gastrointestinal infections
• Prescription: Required; use under medical supervision only

How to use LEVOKILZ 500mg

p>Correct usage of LEVOKILZ 500mg ensures optimal treatment outcomes while minimizing the risk of side effects or bacterial resistance. Always adhere to your doctor’s guidance when taking this medication.

How to take LEVOKILZ 500mg:

• Swallow the tablet whole with a full glass of water. Do not crush or chew the tablet.
• It can be taken with or without food; however, taking it with food may reduce stomach upset.
• Maintain a consistent daily schedule — take it at the same time each day to maintain stable blood levels.
• If taking antacids, iron, or zinc supplements, space them at least 2 hours before or after LEVOKILZ to avoid absorption interference.
• Complete the full course prescribed, even if symptoms improve before the end of treatment.
• If a dose is missed, take it as soon as possible unless the next dose is close. Never double the dose to make up for a missed one.

Mode of Action LEVOKILZ 500mg

LEVOKILZ 500mg acts by disrupting essential bacterial processes needed for survival and replication. Its unique action quickly controls and eliminates the infection.

Mechanism of action:

• Targets and inhibits two critical bacterial enzymes: DNA gyrase and topoisomerase IV.
• DNA gyrase facilitates the supercoiling of bacterial DNA, necessary for replication and repair.
• Topoisomerase IV plays a vital role in the separation of replicated DNA during cell division.
• By blocking these enzymes, LEVOKILZ causes rapid bacterial DNA damage, resulting in cell death.
• The antibiotic demonstrates a bactericidal effect, meaning it directly kills bacteria rather than just inhibiting their growth.

LEVOKILZ 500mg Interactions LEVOKILZ 500mg

Drug interactions can influence how LEVOKILZ 500mg works and may increase the risk of side effects. Inform your healthcare provider about all medications you are taking before starting treatment.

Possible interactions:

• Antacids, Sucralfate, or Supplements: Products containing magnesium, aluminum, iron, or zinc can significantly reduce absorption.
• Warfarin: May enhance anticoagulant effects; monitor INR closely.
• NSAIDs (e.g., ibuprofen): Can increase the risk of central nervous system side effects like seizures.
• Hypoglycemic Agents: Insulin or oral diabetes medications may lead to unpredictable blood sugar changes.
• Corticosteroids: Concurrent use raises the risk of tendon rupture, especially in elderly patients.

Dosage of LEVOKILZ 500mg

The dosage of LEVOKILZ 500mg should be tailored to the infection type, severity, and the patient's renal function. Always follow your doctor’s exact prescription instructions.

Common dosage recommendations:

• Acute sinusitis: 500mg once daily for 10–14 days.
• Community-acquired pneumonia: 500mg once daily for 7–14 days.
• Complicated urinary tract infections: 500mg once daily for 7–14 days.
• Uncomplicated urinary tract infections: 500mg once daily for 3 days.
• Skin and soft tissue infections: 500mg once or twice daily for 7–14 days.

Note: Patients with impaired kidney function may require dose adjustments. Always check renal function before prescribing or adjusting the dose.

Possible side effects of LEVOKILZ 500mg

LEVOKILZ 500mg is generally well tolerated, but as with all medications, it can cause side effects. Most are mild and self-limiting, but some can be serious and require prompt medical attention.

Common side effects:

• Nausea, vomiting
• Diarrhea or constipation
• Headache and dizziness
• Sleep disturbances (insomnia)

Serious side effects:

• Tendon inflammation or rupture, particularly in elderly or corticosteroid-treated patients
• Severe allergic reactions (anaphylaxis, angioedema)
• Seizures and hallucinations (rare)
• Peripheral neuropathy (numbness, tingling in hands/feet)
• Photosensitivity (increased skin sensitivity to sunlight)

Contact a healthcare provider immediately if experiencing severe side effects.

LEVOKILZ 500mg Contraindications LEVOKILZ 500mg

LEVOKILZ 500mg is contraindicated in certain patient groups due to potential risks outweighing the benefits. Always screen patients carefully before prescribing.

Absolute contraindications:

• Known hypersensitivity to Levofloxacin or any quinolone antibiotic
• History of tendon disorders associated with quinolone use
• Children and adolescents (<18 years old), unless no alternative exists
• Pregnancy and breastfeeding, unless absolutely necessary
• Patients with a history of epilepsy or who are prone to seizures
• Severe renal dysfunction without dosage adjustment

Alternative antibiotics with safer profiles are recommended in these cases.

Storage of LEVOKILZ 500mg

Proper storage of LEVOKILZ 500mg ensures its potency and safety for patient use throughout its shelf life.

Storage instructions:

• Store at controlled room temperature, between 15°C and 30°C (59°F–86°F).
• Keep the tablets in their original blister packaging until use to protect them from light and moisture.
• Do not store in a humid or damp place like bathrooms.
• Keep out of reach of children and pets.
• Do not use the medicine past its expiry date; safely dispose of expired medication following local guidelines.