ADALAT LA 30 Tablets/Modified Release

What is ADALAT LA 30

ADALAT LA 30 mg is a prolonged-release tablet containing Nifedipine, a calcium channel blocker used to treat high blood pressure and angina (chest pain). The "LA" denotes "long-acting," indicating that the medication is formulated to release the active ingredient slowly over time, allowing for once-daily dosing. Key Features: Active Ingredient: Nifedipine Formulation: Prolonged-release tablet Indications: Hypertension (high blood pressure) Chronic stable angina Vasospastic (Prinzmetal's) angina Manufacturer: Bayer Healthcare AG

How to use ADALAT LA 30

Administration Guidelines: Dosage: Typically, one tablet (30 mg) taken once daily. Timing: Take at the same time each day, preferably in the morning. Method: Swallow the tablet whole with a glass of water. Do not bite, chew, or break the tablet, as this can affect the prolonged-release mechanism. Food: Can be taken with or without food. Grapefruit Warning: Do not consume grapefruit or grapefruit juice while taking this medication, as it can increase the levels of Nifedipine in your blood, leading to potential side effects. patient-info.co.uk patient-info.co.uk Missed Dose: If you miss a dose, take it as soon as you remember. If it's almost time for your next dose, skip the missed dose. Do not take a double dose to make up for a missed one. patient-info.co.uk Overdose: In case of overdose, seek immediate medical attention. Symptoms may include low blood pressure, irregular heartbeat, high blood sugar, and unconsciousness.

Mode of Action ADALAT LA 30

Nifedipine, the active ingredient in ADALAT LA 30, is a calcium channel blocker that works by inhibiting the influx of calcium ions into vascular smooth muscle and cardiac muscle during depolarization. Physiological Effects: Vasodilation: Relaxes blood vessels, reducing peripheral resistance and lowering blood pressure. Reduced Myocardial Oxygen Demand: Decreases the workload on the heart, helping to alleviate angina. Improved Coronary Blood Flow: Dilates coronary arteries, enhancing oxygen delivery to the heart muscle.

ADALAT LA 30 Interactions ADALAT LA 30

Drug Interactions: CYP3A4 Inhibitors: Medications like ketoconazole, erythromycin, and ritonavir can increase Nifedipine levels, enhancing its effects and potential side effects. CYP3A4 Inducers: Drugs such as rifampin, carbamazepine, and phenytoin can decrease Nifedipine levels, reducing its efficacy. Beta-blockers: Concurrent use may increase the risk of heart failure or bradycardia. Digoxin: Nifedipine can increase digoxin levels; monitoring is advised. Quinidine: May alter plasma concentrations of both drugs. Food Interactions: Grapefruit Juice: Avoid consumption, as it can significantly increase Nifedipine levels, leading to enhanced effects and side effects.

Dosage of ADALAT LA 30

Standard Dosage: Adults: One 30 mg tablet once daily. Dose Adjustment: Depending on the patient's response, the dose may be adjusted. Special Populations: Elderly: No specific dose adjustment required, but caution is advised. Renal Impairment: No dosage adjustment typically necessary. Hepatic Impairment: Use with caution; metabolism may be prolonged. Children: Not recommended for use in individuals under 18 years of age.

Possible side effects of ADALAT LA 30

Common Side Effects (may affect up to 1 in 10 people): Headache Flushing General feeling of being unwell Constipation Swelling, particularly of the ankles and legs farmacoinc.com +1 medcentral.com +1 farmacoinc.com +3 assetpharmacy.com +3 patient-info.co.uk +3 Uncommon Side Effects (may affect up to 1 in 100 people): Stomach pain Low blood pressure upon standing Fainting Irregular heartbeat Dry mouth Indigestion Muscle cramps Joint swelling Sleep disorders Anxiety Nosebleeds Dizziness Blurred vision myhealthbox.eu +9 assetpharmacy.com +9 patient-info.co.uk +9 medcentral.com +2 patient-info.co.uk +2 assetpharmacy.com +2 Rare Side Effects (may affect up to 1 in 1,000 people): Pins and needles Inflammation of the gums assetpharmacy.com +1 patient-info.co.uk +1 Serious Side Effects: Severe allergic reactions, including swelling of the face, lips, or throat Rapid heartbeat Shortness of breath Skin reactions, including blistering or peeling myhealthbox.eu +5 patient-info.co.uk +5 farmacoinc.com +5 Note: If you experience any severe or persistent side effects, contact your healthcare provider immediately.

ADALAT LA 30 Contraindications ADALAT LA 30

Do not take ADALAT LA 30 if you: Are allergic to Nifedipine or any other ingredients in the tablet. Have cardiogenic shock. Have severe aortic stenosis. Have unstable angina or have had a recent heart attack. Have significant liver impairment. Have a history of gastrointestinal obstruction or narrowing. Have inflammatory bowel disease. Are taking rifampicin. medicines.org.uk

Storage of ADALAT LA 30

Storage Guidelines: Store at room temperature, not exceeding 30°C. Keep the tablets in their original packaging to protect from light and moisture. Keep out of reach and sight of children. Do not use after the expiry date stated on the packaging.