What is ADACEL
ADACEL is a combination vaccine formulated to provide active booster immunization against three serious bacterial infections:
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Tetanus: Caused by Clostridium tetani, leading to painful muscle stiffness and spasms.
Diphtheria: Caused by Corynebacterium diphtheriae, affecting the throat and potentially leading to heart and nerve damage.
Pertussis (Whooping Cough): Caused by Bordetella pertussis, leading to severe coughing spells that can interfere with breathing.
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ADACEL is approved for use in individuals aged 10 through 64 years as a single-dose booster vaccine. It is also recommended during the third trimester of pregnancy to protect newborns from pertussis in their early months of life.
How to use ADACEL
Administration Guidelines:
Dosage: A single 0.5 mL dose administered intramuscularly.
Injection Site: Preferably the deltoid muscle of the upper arm.
Booster Timing:
For adolescents and adults: Administer at least 5 years after the last dose of DTaP or Td vaccine.
For pregnant women: Administer during the third trimester (preferably between 27 and 36 weeks gestation).
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Co-administration with Other Vaccines:
ADACEL can be administered concurrently with other vaccines, using separate syringes and injection sites.
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Mode of Action ADACEL
ADACEL stimulates the body's immune system to produce antibodies against the toxins produced by the bacteria responsible for tetanus, diphtheria, and pertussis.
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Components and Their Functions:
Tetanus Toxoid: Induces immunity against tetanus toxin.
Diphtheria Toxoid: Induces immunity against diphtheria toxin.
Acellular Pertussis Antigens:
Pertussis Toxin (PT): Neutralizes the main toxin produced by B. pertussis.
Filamentous Hemagglutinin (FHA): Prevents bacterial adhesion to respiratory epithelial cells.
Pertactin (PRN): Aids in bacterial adhesion and invasion.
Fimbriae Types 2 and 3 (FIM): Enhance bacterial attachment to host cells.
By introducing these antigens, ADACEL primes the immune system to recognize and combat these pathogens upon future exposures.
ADACEL Interactions ADACEL
Drug Interactions:
No significant drug interactions have been reported with ADACEL. However, immunosuppressive therapies may reduce the vaccine's effectiveness.
Disease Interactions:
Individuals with the following conditions should consult healthcare providers before vaccination:
Neurologic Disorders: History of encephalopathy not attributable to another identifiable cause within 7 days of a previous pertussis-containing vaccine.
Immunodeficiency: May result in a diminished immune response to the vaccine.
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Dosage of ADACEL
Standard Dosage:
A single 0.5 mL intramuscular injection.
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Booster Recommendations:
Adolescents and Adults (10–64 years):
Administer at least 5 years after the last dose of DTaP or Td vaccine.
Pregnant Women:
Administer during each pregnancy, preferably between 27 and 36 weeks gestation, to protect the newborn from pertussis.
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Note: The safety and efficacy of ADACEL in individuals under 10 years or over 64 years have not been established.
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Possible side effects of ADACEL
Common Side Effects:
Local Reactions:
Pain, redness, or swelling at the injection site.
Systemic Reactions:
Fever.
Headache.
Fatigue.
Gastrointestinal symptoms such as nausea, vomiting, or diarrhea.
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Less Common Side Effects:
Body aches.
Mild fever.
Diarrhea.
Tiredness.
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Rare but Serious Side Effects:
Anaphylaxis (a severe allergic reaction).
Guillain-Barré Syndrome.
Encephalopathy.
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Note: Any unusual or severe symptoms following vaccination should be reported to a healthcare provider immediately.
ADACEL Contraindications ADACEL
Absolute Contraindications:
Severe allergic reaction (e.g., anaphylaxis) to any component of ADACEL or following a previous dose of a tetanus, diphtheria, or pertussis-containing vaccine.
Encephalopathy within 7 days of a previous pertussis-containing vaccine not attributable to another identifiable cause.
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Precautions:
Progressive or unstable neurologic disorders, uncontrolled seizures, or progressive encephalopathy.
Moderate or severe acute illness with or without fever (vaccination should be postponed until recovery).
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Storage of ADACEL
Storage Conditions:
Temperature: Store refrigerated at 2°C to 8°C (36°F to 46°F).
Do Not Freeze: Freezing destroys the vaccine's potency.
Light Protection: Keep the vaccine in its original packaging to protect from light.
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Handling Instructions:
If the vaccine has been frozen, it should be discarded.
Before administration, visually inspect the vaccine for particulate matter and discoloration.
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ADACEL features an exceptional active ingredient renowned for its potent effects, comprising Tetanus Toxoid -
Diphtheria Toxoid,
Pertussis Toxoid Adsorbed (PT) ,
Filamentous Haemagglutinin (FHA),
Pertactin Adsorbed (PRN),
Fimbriae Types 2 and 3 Adsorbed (FIM). This powerful formulation provides a superior solution for addressing diverse health concerns. With 5 Lf/0.5 ml, 2 Lf/0.5 ml, 2.5 ?g/0.5 ml, 5 ?g/0.5 ml, 3 ?g/0.5 ml, 5 ?g/0.5 ml concentration and an easily manageable Suspension for injection, it remains a preferred option for countless individuals seeking effective treatment.
Introduction
All you need to know about ADACEL .
Welcome to Dwaey, specifically on ADACEL page.
This medicine contains an important and useful components, as it consists of Tetanus Toxoid -
Diphtheria Toxoid,
Pertussis Toxoid Adsorbed (PT) ,
Filamentous Haemagglutinin (FHA),
Pertactin Adsorbed (PRN),
Fimbriae Types 2 and 3 Adsorbed (FIM).
ADACEL is available in the market in concentration 5 Lf/0.5 ml, 2 Lf/0.5 ml, 2.5 ?g/0.5 ml, 5 ?g/0.5 ml, 3 ?g/0.5 ml, 5 ?g/0.5 ml and in the form of Suspension for injection.
SANOFI PASTEUR LIMITED is the producer of ADACEL and it is imported from CANADA,
The most popular alternatives of ADACEL are listed downward .
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Active Substance
Tetanus Toxoid -
Diphtheria Toxoid,
Pertussis Toxoid Adsorbed (PT) ,
Filamentous Haemagglutinin (FHA),
Pertactin Adsorbed (PRN),
Fimbriae Types 2 and 3 Adsorbed (FIM)
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Size
0.5 ml Single dose Glass Vial
-
Indications
- No indications available.
-
Type
-
Company
Frequently Asked Questions
ADACEL should be stored according to the instructions provided by SANOFI PASTEUR LIMITED.
In general, it is recommended to store ADACEL in a cool, dry place, away from direct sunlight
and out of the reach of children.
The duration of treatment with ADACEL may vary depending on the condition being treated
and the guidance of your healthcare provider. It is important to follow the prescribed treatment
plan and continue taking ADACEL for the recommended duration, even if your symptoms improve.
If you have any concerns or questions about the duration of treatment, consult your healthcare provider.
It is important to check with your healthcare provider or read the medication label for specific
instructions regarding alcohol consumption while taking ADACEL. Some medications, including
ADACEL, may have interactions with alcohol that can reduce effectiveness, increase side
effects, or pose other risks to your health. It is best to follow the guidance provided by your
healthcare professional.
If you miss a dose of ADACEL, take it as soon as you remember. However, if it is close
to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing
schedule. Do not take a double dose to make up for a missed one unless advised by your healthcare provider.
No, do not stop taking ADACEL without consulting your healthcare provider, even if your
symptoms improve. It is important to complete the full course of treatment as prescribed. Stopping
the medication prematurely may lead to a relapse or incomplete resolution of the condition. If you
have concerns about the duration of treatment, consult your healthcare provider for guidance.
It is important to consult your healthcare provider before taking ADACEL if you are
pregnant or breastfeeding. They will be able to assess the potential risks and benefits based on your
specific situation. Please note that the safety and suitability of ADACEL during pregnancy
or breastfeeding may depend on the active substance [Active Substance], concentration 5 Lf/0.5 ml, 2 Lf/0.5 ml, 2.5 ?g/0.5 ml, 5 ?g/0.5 ml, 3 ?g/0.5 ml, 5 ?g/0.5 ml,
and the specific recommendations of SANOFI PASTEUR LIMITED.
The effects of ADACEL on your ability to drive or operate machinery can vary depending on
the active substance [Active Substance], concentration 5 Lf/0.5 ml, 2 Lf/0.5 ml, 2.5 ?g/0.5 ml, 5 ?g/0.5 ml, 3 ?g/0.5 ml, 5 ?g/0.5 ml, and individual factors.
Some medications may cause drowsiness, dizziness, or other side effects that can impair your judgment
or coordination. It is important to read the medication label or consult your healthcare provider to
understand any potential effects on your ability to perform tasks that require alertness.
The instructions for taking ADACEL with or without food may vary depending on the medication
and the recommendations of SANOFI PASTEUR LIMITED. Some medications may be more effective when taken with
food to enhance absorption or reduce stomach irritation, while others may need to be taken on an empty
stomach for optimal absorption. Read the medication label or consult your healthcare provider for specific instructions.
The use of ADACEL in children or elderly individuals may depend on various factors, including
the specific medication, type Suspension for injection, and the recommendations of SANOFI PASTEUR LIMITED. Some
medications may have specific dosing instructions or precautions for these age groups. Consult your
healthcare provider or read the medication label for information regarding the safe and appropriate use
of ADACEL in children or elderly individuals.
Dwaey
All medical information published on the Dwaey website aims to increase medical awareness and health education among users. However, it is not a substitute for professional medical advice. Always consult with a specialist doctor. We strongly advise against using any information or medicine found on the site without referring to your healthcare provider.
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