DAPHNE Tablets/Film-coated

What is DAPHNE

DAPHNE is a combined oral contraceptive that contains two active ingredients: Ethinylestradiol and Cyproterone acetate. Ethinylestradiol is a synthetic form of estrogen, while Cyproterone acetate is a synthetic progestogen. This combination is effective in preventing ovulation, regulating the menstrual cycle, and managing conditions like acne and hirsutism. DAPHNE is particularly beneficial for women seeking reliable contraception along with treatment for hormonal imbalances.

The mechanism of action for DAPHNE involves the suppression of gonadotropin release from the pituitary gland. This leads to the inhibition of ovulation. Additionally, it alters the endometrial lining, making it less suitable for implantation and thickens cervical mucus, thus preventing sperm passage. These multifaceted actions contribute to its effectiveness as a contraceptive and therapeutic agent.

How to use DAPHNE

• Take DAPHNE exactly as prescribed by your healthcare provider, typically starting on the first day of your menstrual cycle.
• Swallow the tablet whole with a glass of water; do not chew or crush.
• It is usually taken once daily for 21 consecutive days, followed by a 7-day break during which withdrawal bleeding occurs.
• If a dose is missed, take it as soon as you remember. If it is close to the time of your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
• Consult your healthcare provider for specific instructions if you miss more than one dose or experience vomiting or diarrhea.

Mode of Action DAPHNE

The combination of Ethinylestradiol and Cyproterone acetate works synergistically to achieve effective contraception and manage other conditions. Ethinylestradiol primarily prevents ovulation, while Cyproterone acetate provides additional benefits by regulating hormonal imbalances that can lead to acne and excessive hair growth. This dual action makes DAPHNE suitable for women not only seeking contraception but also those looking to manage symptoms associated with polycystic ovary syndrome (PCOS) or other hormonal disorders.

By inhibiting the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), DAPHNE effectively controls the menstrual cycle and reduces the risk of ovarian cyst formation.

DAPHNE Interactions DAPHNE

• Inform your healthcare provider about all medications, including over-the-counter drugs and supplements, you are currently taking to prevent interactions.
• Be cautious when using DAPHNE with other hormonal treatments, as this may affect the efficacy of the contraceptive.
• Antibiotics and certain antifungal medications may decrease the effectiveness of DAPHNE; thus, additional contraceptive methods may be necessary during and after treatment.
• Consult your healthcare provider if you have a history of liver problems or any conditions that may affect liver function.

Dosage of DAPHNE

The recommended dosage of DAPHNE is one tablet daily for 21 days, followed by a 7-day pill-free interval. During this break, withdrawal bleeding typically occurs. However, if you forget to take a tablet or experience gastrointestinal disturbances, consult your healthcare provider for specific dosage instructions. Your provider will tailor the dosage based on your individual health needs and medical history.

It is important to adhere strictly to the prescribed regimen to maintain consistent hormone levels and enhance contraceptive effectiveness. Your healthcare provider may adjust the dosage if you experience side effects or if the contraceptive does not meet your needs.

Possible side effects of DAPHNE

• Common side effects include nausea, headaches, breast tenderness, and mood changes. These effects are usually mild and tend to improve over time.
• Less common side effects may include breakthrough bleeding, weight changes, and changes in libido.
• Serious side effects can occur but are rare, such as blood clots, liver tumors, and severe allergic reactions. Seek immediate medical attention if you experience symptoms like leg swelling, chest pain, sudden headaches, or jaundice.

DAPHNE Contraindications DAPHNE

Information not available.

Storage of DAPHNE

• Store DAPHNE at room temperature, away from moisture and heat. Ensure that it is kept in its original packaging to protect it from light.
• Keep the medication out of reach of children and pets to prevent accidental ingestion.
• Do not use DAPHNE after the expiration date printed on the packaging. Dispose of any unused medication safely, following local regulations for medication disposal.