ACID CONCENTRATE FOR BICARBONATE HAEMODIALYSIS KSP-04 Dialysis Fluid

What is ACID CONCENTRATE FOR BICARBONATE HAEMODIALYSIS KSP-04

ACID CONCENTRATE FOR BICARBONATE HAEMODIALYSIS KSP-04 is an acidic component used in the preparation of dialysate for hemodialysis. It is formulated to be mixed with a bicarbonate concentrate and purified water to create a final dialysate solution. This dialysate facilitates the exchange of solutes and removal of toxins from the blood during dialysis sessions. Composition per Liter: Sodium Chloride: 161.43 g Potassium Chloride: 5.49 g Calcium Chloride: 9.75 g Magnesium Chloride: 3.74 g Glacial Acetic Acid: 8.85 g Purified Water: q.s. to 1 liter Medex +2 Medex +2 My Health Box +2 Key Features: Provides essential electrolytes to maintain physiological balance during dialysis. Contains acetic acid to stabilize the pH of the dialysate solution. Designed for use with bicarbonate concentrates in a three-stream dialysis system

How to use ACID CONCENTRATE FOR BICARBONATE HAEMODIALYSIS KSP-04

Preparation: Dilution: Mix the acid concentrate with a bicarbonate concentrate and purified water in a three-stream dialysis machine. The typical dilution ratio is: Acid Concentrate: 1 part Bicarbonate Concentrate: 1.83 parts Purified Water: 34 parts Medex Mixing: Ensure thorough mixing to achieve a homogeneous dialysate solution. Quality Control: Verify the conductivity and pH of the final dialysate to ensure it meets prescribed standards. Administration: The prepared dialysate is delivered to the dialyzer where it facilitates the exchange of waste products and electrolytes between the patient's blood and the dialysate. Precautions: Do not use the acid concentrate alone; it must be combined with a bicarbonate concentrate and purified water. Use only with dialysis machines compatible with three-stream systems. Ensure all components are within their expiration dates and have been stored properly

Mode of Action ACID CONCENTRATE FOR BICARBONATE HAEMODIALYSIS KSP-04

The acid concentrate plays a crucial role in the dialysis process by contributing to the composition of the dialysate solution. Mechanism: Electrolyte Balance: The concentrate provides essential electrolytes (sodium, potassium, calcium, magnesium) that help maintain the patient's electrolyte balance during dialysis. Acid-Base Regulation: Acetic acid in the concentrate helps stabilize the pH of the dialysate. During dialysis, acetic acid is metabolized to bicarbonate in the body, aiding in correcting metabolic acidosis. PMC Osmotic Gradient: The presence of dextrose creates an osmotic gradient that facilitates the removal of excess fluid from the patient's blood. Outcome: The combined effect of these components ensures effective removal of waste products, maintenance of electrolyte balance, and correction of acid-base disturbances in patients undergoing hemodialysis.

ACID CONCENTRATE FOR BICARBONATE HAEMODIALYSIS KSP-04 Interactions ACID CONCENTRATE FOR BICARBONATE HAEMODIALYSIS KSP-04

While the acid concentrate itself is not administered directly to patients, its components can interact with the patient's physiological status and medications. Potential Interactions: Electrolyte Levels: The electrolyte composition of the dialysate can influence serum electrolyte levels, potentially interacting with medications that affect electrolyte balance. Acid-Base Balance: The acid-base status influenced by the dialysate can affect the pharmacokinetics of certain drugs, altering their efficacy or toxicity. Clinical Considerations: Monitor patients for signs of electrolyte imbalances, especially if they are on medications that affect electrolyte levels. Adjust medication dosages as necessary based on the patient's response to dialysis and changes in laboratory values.

Dosage of ACID CONCENTRATE FOR BICARBONATE HAEMODIALYSIS KSP-04

Standard Dosage: Typically, 5 liters of acid concentrate are used per dialysis session. This is mixed with appropriate volumes of bicarbonate concentrate and purified water to prepare the final dialysate solution. Medex Customization: The exact volume may be adjusted based on the patient's individual needs, dialysis prescription, and the dialysis machine's specifications. Administration: The prepared dialysate is used during the dialysis session, with the flow rate and duration determined by the patient's treatment plan. Monitoring: Regularly monitor the patient's vital signs, electrolyte levels, and acid-base status during and after dialysis sessions to ensure treatment efficacy and safety.

Possible side effects of ACID CONCENTRATE FOR BICARBONATE HAEMODIALYSIS KSP-04

While the acid concentrate itself is not directly administered to patients, improper preparation or use can lead to adverse effects. Potential Side Effects: Electrolyte Imbalances: Incorrect electrolyte concentrations in the dialysate can lead to hypo- or hypernatremia, hypo- or hyperkalemia, and other disturbances. Acid-Base Disorders: Improper acid-base balance in the dialysate can result in metabolic acidosis or alkalosis. Hypotension: Rapid fluid removal or incorrect dialysate composition can cause low blood pressure during dialysis. Muscle Cramps: Electrolyte shifts during dialysis may lead to muscle cramps. Preventive Measures: Ensure accurate preparation of the dialysate with correct concentrations of all components. Monitor patients closely during dialysis sessions for any signs of adverse effects.

ACID CONCENTRATE FOR BICARBONATE HAEMODIALYSIS KSP-04 Contraindications ACID CONCENTRATE FOR BICARBONATE HAEMODIALYSIS KSP-04

Absolute Contraindications: Known hypersensitivity to any component of the concentrate. Relative Contraindications: Hyperkalemia: Use with caution in patients with elevated serum potassium levels, as the concentrate contains potassium chloride. Hypercalcemia: Patients with high serum calcium levels should be monitored closely due to the calcium content in the concentrate. Clinical Considerations: Evaluate the patient's electrolyte levels and overall clinical status before initiating dialysis with this concentrate. Adjust the dialysate composition as necessary to meet individual patient needs.

Storage of ACID CONCENTRATE FOR BICARBONATE HAEMODIALYSIS KSP-04

Storage Conditions: Store at temperatures below 30°C. Medex Keep the container tightly closed when not in use. Protect from light and moisture. Shelf Life: Use before the expiration date indicated on the container. Once opened, the solution should be used within 96 hours. Medex Handling Precautions: Inspect the solution for any visible particles or discoloration before use. Do not use if the solution appears cloudy or contains precipitates. Dispose of any unused solution according to local regulations.