What is 5% w/v Dextrose & 0.9% w/v Sodium Chloride Injection, USP [Medisal]
5% w/v Dextrose & 0.9% w/v Sodium Chloride Injection USP is a sterile, non-pyrogenic intravenous (IV) solution supplied in a 500ml polypropylene bottle. It contains:
- Dextrose (anhydrous) 5% w/v: A form of glucose, which is a simple sugar used by the body for energy.
- Sodium chloride 0.9% w/v: Also known as normal saline, it replenishes electrolytes and maintains fluid balance.
This isotonic solution is commonly used in clinical settings for fluid replacement, correction of electrolyte imbalances, and as a vehicle for the administration of compatible medications. The combination of dextrose and saline offers both caloric supply and sodium replenishment, which is essential for maintaining hemodynamic stability, particularly in patients who are dehydrated or require nutritional support.
It is typically used under the supervision of healthcare professionals in hospital or clinical environments, particularly for:
- Dehydration treatment
- Maintenance of fluid and electrolyte balance during surgery or illness
- Supportive therapy for patients unable to ingest fluids orally
- Vehicle for compatible drug infusion
How to use 5% w/v Dextrose & 0.9% w/v Sodium Chloride Injection, USP [Medisal]
The administration of this IV solution should always be conducted by a healthcare professional trained in intravenous therapy. Usage guidelines include:
- Route of Administration: Intravenous (IV) infusion via sterile technique.
- Preparation: Ensure the solution is clear and free of particulate matter before use. Do not use if the bottle is damaged or the solution appears discolored or cloudy.
- Dosage: Individualized based on patient’s clinical condition, age, body weight, electrolyte status, and fluid requirements.
- Infusion Rate: Typically ranges between 50 to 250 ml/hour depending on patient’s needs. Infusion should be adjusted to avoid fluid overload, especially in patients with renal or cardiac impairment.
- Monitoring: Regular monitoring of fluid input/output, serum electrolytes, blood glucose levels, and renal function is essential during prolonged therapy.
Before using this solution for drug dilution or administration, healthcare professionals must check the compatibility of the added substance. Aseptic technique must always be observed to prevent infection.
Once the infusion is complete, any unused portion should be discarded. Do not reconnect partially used bottles.
Mode of Action 5% w/v Dextrose & 0.9% w/v Sodium Chloride Injection, USP [Medisal]
This dual-component IV solution acts by providing:
- Dextrose:
- Supplies calories that can be immediately utilized for energy production, especially during catabolic states.
- Reduces protein catabolism by sparing amino acids from being used as an energy source.
- Helps in preventing ketosis when carbohydrate intake is inadequate.
- Sodium Chloride (NaCl):
- Maintains osmotic pressure and hydration status.
- Replenishes extracellular sodium and chloride ions lost through sweat, vomiting, diarrhea, or other causes.
- Plays a vital role in nerve transmission and muscle contraction.
Collectively, this solution maintains both energy balance and extracellular fluid volume, which is critical in patients with fluid and electrolyte disturbances. The isotonic nature of the solution ensures that there is no net fluid shift across cellular membranes, reducing the risk of cellular swelling or dehydration.
5% w/v Dextrose & 0.9% w/v Sodium Chloride Injection, USP [Medisal] Interactions 5% w/v Dextrose & 0.9% w/v Sodium Chloride Injection, USP [Medisal]
This IV fluid can interact with other medications or substances administered concurrently. Important interaction considerations include:
- Drug compatibility: Some drugs may precipitate or degrade when mixed with this solution. Always confirm compatibility before mixing or co-administering.
- Diuretics (e.g., furosemide, hydrochlorothiazide): Can enhance sodium loss or alter fluid balance, requiring dosage adjustments or close monitoring.
- Corticosteroids (e.g., prednisone): May promote sodium retention and fluid overload, especially in patients with heart or kidney conditions.
- Insulin: The dextrose component may necessitate increased insulin requirements in diabetic patients. Blood glucose levels should be monitored frequently.
- Potassium-sparing or depleting agents: The sodium load in this infusion may interfere with serum potassium levels and the effectiveness of such drugs.
- Antihypertensives: Fluid volume expansion may reduce the effectiveness of antihypertensive drugs.
Consult with a pharmacist or medical specialist for safe co-administration practices. Use extreme caution when combining this solution with hypertonic agents or drugs known to affect fluid or electrolyte balance.
Dosage of 5% w/v Dextrose & 0.9% w/v Sodium Chloride Injection, USP [Medisal]
The dosage and rate of administration are tailored to the patient’s clinical condition and therapeutic goals. General guidelines include:
- Adults:
- Typical maintenance infusion: 500 ml to 2 liters per day, based on hydration and electrolyte needs.
- Rate: 50–150 ml/hour depending on clinical indication and comorbid conditions.
- Children:
- Dosing is weight-based: commonly 20-100 ml/kg/day.
- Close monitoring required due to increased sensitivity to fluid and electrolyte shifts.
- Elderly:
- Begin at lower infusion rates due to risk of cardiac or renal impairment.
Special considerations:
- Adjust dose in patients with renal, cardiac, or hepatic impairment.
- Do not exceed maximum fluid allowance to avoid volume overload or pulmonary edema.
- Always use infusion pumps for accurate delivery in pediatric or critical care settings.
Possible side effects of 5% w/v Dextrose & 0.9% w/v Sodium Chloride Injection, USP [Medisal]
While generally well tolerated, this IV solution may cause side effects, especially when used improperly or in high volumes. Possible adverse effects include:
- Common:
- Injection site pain or inflammation
- Local phlebitis or thrombophlebitis
- Metabolic:
- Hyperglycemia, especially in diabetic patients
- Electrolyte imbalance, such as hypernatremia or hypokalemia
- Fluid overload leading to edema or hypertension
- Severe but rare:
- Pulmonary edema
- Congestive heart failure in susceptible individuals
- Acid-base imbalances
Immediate medical attention should be sought if symptoms such as difficulty breathing, chest discomfort, or sudden swelling occur.
5% w/v Dextrose & 0.9% w/v Sodium Chloride Injection, USP [Medisal] Contraindications 5% w/v Dextrose & 0.9% w/v Sodium Chloride Injection, USP [Medisal]
This solution is contraindicated in patients with specific medical conditions where the administration could be harmful. These include:
- Severe renal impairment: Due to the risk of fluid retention and electrolyte accumulation.
- Uncontrolled diabetes mellitus: Because of the dextrose content, which may worsen hyperglycemia.
- Congestive heart failure or pulmonary edema: The sodium and fluid load may exacerbate volume overload.
- Hypernatremia or fluid retention disorders: Worsening of sodium imbalance may occur.
- Known hypersensitivity: Rare, but any hypersensitivity to components is a contraindication.
This IV solution should be used with caution in elderly patients, neonates, or those with liver disease. Always assess risk versus benefit before initiating therapy in borderline cases.
Storage of 5% w/v Dextrose & 0.9% w/v Sodium Chloride Injection, USP [Medisal]
Proper storage is essential to ensure the safety, sterility, and efficacy of the solution. Recommended storage conditions include:
- Temperature: Store at 15°C to 25°C (59°F to 77°F).
- Keep away from direct sunlight and freezing conditions.
- Protect from excessive heat and humidity.
- Container integrity: Use only if the polypropylene bottle is intact. Discard if the solution is discolored, cloudy, or contains particulates.
- Do not use beyond expiration date.
Once opened, the solution should be used immediately to avoid contamination. Unused portions must not be stored for later use due to the risk of microbial growth.
5% w/v Dextrose & 0.9% w/v Sodium Chloride Injection, USP [Medisal] features an exceptional active ingredient renowned for its potent effects, comprising Dextrose (anhydrous), Sodium chloride. This powerful formulation provides a superior solution for addressing diverse health concerns. With 50mg, 9mg/ml concentration and an easily manageable Injection/Solution for, it remains a preferred option for countless individuals seeking effective treatment.
Introduction
All you need to know about 5% w/v Dextrose & 0.9% w/v Sodium Chloride Injection, USP [Medisal] .
Welcome to Dwaey, specifically on 5% w/v Dextrose & 0.9% w/v Sodium Chloride Injection, USP [Medisal] page.
This medicine contains an important and useful components, as it consists of Dextrose (anhydrous), Sodium chloride.
5% w/v Dextrose & 0.9% w/v Sodium Chloride Injection, USP [Medisal] is available in the market in concentration 50mg, 9mg/ml and in the form of Injection/Solution for.
MEDISAL PHARMACEUTICALS INDUSTRY LLC is the producer of 5% w/v Dextrose & 0.9% w/v Sodium Chloride Injection, USP [Medisal] and it is imported from UAE,
The most popular alternatives of 5% w/v Dextrose & 0.9% w/v Sodium Chloride Injection, USP [Medisal] are listed downward .
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Active Substance
Dextrose (anhydrous), Sodium chloride
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Size
500ml Polypropylene Bottle
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Indications
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Type
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Company
MEDISAL PHARMACEUTICALS INDUSTRY LLC
Frequently Asked Questions
5% w/v Dextrose & 0.9% w/v Sodium Chloride Injection, USP [Medisal] should be stored according to the instructions provided by MEDISAL PHARMACEUTICALS INDUSTRY LLC.
In general, it is recommended to store 5% w/v Dextrose & 0.9% w/v Sodium Chloride Injection, USP [Medisal] in a cool, dry place, away from direct sunlight
and out of the reach of children.
The duration of treatment with 5% w/v Dextrose & 0.9% w/v Sodium Chloride Injection, USP [Medisal] may vary depending on the condition being treated
and the guidance of your healthcare provider. It is important to follow the prescribed treatment
plan and continue taking 5% w/v Dextrose & 0.9% w/v Sodium Chloride Injection, USP [Medisal] for the recommended duration, even if your symptoms improve.
If you have any concerns or questions about the duration of treatment, consult your healthcare provider.
It is important to check with your healthcare provider or read the medication label for specific
instructions regarding alcohol consumption while taking 5% w/v Dextrose & 0.9% w/v Sodium Chloride Injection, USP [Medisal]. Some medications, including
5% w/v Dextrose & 0.9% w/v Sodium Chloride Injection, USP [Medisal], may have interactions with alcohol that can reduce effectiveness, increase side
effects, or pose other risks to your health. It is best to follow the guidance provided by your
healthcare professional.
If you miss a dose of 5% w/v Dextrose & 0.9% w/v Sodium Chloride Injection, USP [Medisal], take it as soon as you remember. However, if it is close
to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing
schedule. Do not take a double dose to make up for a missed one unless advised by your healthcare provider.
No, do not stop taking 5% w/v Dextrose & 0.9% w/v Sodium Chloride Injection, USP [Medisal] without consulting your healthcare provider, even if your
symptoms improve. It is important to complete the full course of treatment as prescribed. Stopping
the medication prematurely may lead to a relapse or incomplete resolution of the condition. If you
have concerns about the duration of treatment, consult your healthcare provider for guidance.
It is important to consult your healthcare provider before taking 5% w/v Dextrose & 0.9% w/v Sodium Chloride Injection, USP [Medisal] if you are
pregnant or breastfeeding. They will be able to assess the potential risks and benefits based on your
specific situation. Please note that the safety and suitability of 5% w/v Dextrose & 0.9% w/v Sodium Chloride Injection, USP [Medisal] during pregnancy
or breastfeeding may depend on the active substance [Active Substance], concentration 50mg, 9mg/ml,
and the specific recommendations of MEDISAL PHARMACEUTICALS INDUSTRY LLC.
The effects of 5% w/v Dextrose & 0.9% w/v Sodium Chloride Injection, USP [Medisal] on your ability to drive or operate machinery can vary depending on
the active substance [Active Substance], concentration 50mg, 9mg/ml, and individual factors.
Some medications may cause drowsiness, dizziness, or other side effects that can impair your judgment
or coordination. It is important to read the medication label or consult your healthcare provider to
understand any potential effects on your ability to perform tasks that require alertness.
The instructions for taking 5% w/v Dextrose & 0.9% w/v Sodium Chloride Injection, USP [Medisal] with or without food may vary depending on the medication
and the recommendations of MEDISAL PHARMACEUTICALS INDUSTRY LLC. Some medications may be more effective when taken with
food to enhance absorption or reduce stomach irritation, while others may need to be taken on an empty
stomach for optimal absorption. Read the medication label or consult your healthcare provider for specific instructions.
The use of 5% w/v Dextrose & 0.9% w/v Sodium Chloride Injection, USP [Medisal] in children or elderly individuals may depend on various factors, including
the specific medication, type Injection/Solution for, and the recommendations of MEDISAL PHARMACEUTICALS INDUSTRY LLC. Some
medications may have specific dosing instructions or precautions for these age groups. Consult your
healthcare provider or read the medication label for information regarding the safe and appropriate use
of 5% w/v Dextrose & 0.9% w/v Sodium Chloride Injection, USP [Medisal] in children or elderly individuals.
Dwaey
All medical information published on the Dwaey website aims to increase medical awareness and health education among users. However, it is not a substitute for professional medical advice. Always consult with a specialist doctor. We strongly advise against using any information or medicine found on the site without referring to your healthcare provider.
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