What is 5% w/v DEXTROSE & 0.225% w/v SODIUM CHLORIDE INJECTION USP
5% w/v Dextrose & 0.225% w/v Sodium Chloride (MEDISAL) is a sterile, non-pyrogenic intravenous (IV) solution used to provide both fluid replenishment and minimal electrolyte replacement. It comes in a 50ml plastic bag, ideal for controlled or low-volume fluid administration, particularly in pediatric or neonatal patients, or where precise fluid management is required.
- Composition:
- Dextrose (anhydrous) 5% w/v – serves as a source of energy.
- Sodium Chloride 0.225% w/v – provides essential sodium and chloride ions.
- Form: Infusion/Solution for IV use
- Packaging Size: 50ml plastic bag (single-use)
This solution is isotonic to slightly hypotonic, depending on the patient’s serum osmolarity. It’s commonly used in maintenance IV therapy, especially for children, or as part of a larger therapeutic regimen in adults who require limited sodium but still need hydration and energy supplementation.
How to use 5% w/v DEXTROSE & 0.225% w/v SODIUM CHLORIDE INJECTION USP
This medicine should be administered only under medical supervision via intravenous infusion. The route of administration is through a sterile, pyrogen-free IV line, often using an infusion pump for accurate control, particularly when used in neonatal or pediatric care.
- Preparation:
- Inspect the bag for leaks, cloudiness, or particulates before use.
- Ensure aseptic technique while connecting the infusion set.
- Administration:
- Infuse slowly as directed by the physician or according to clinical protocol.
- Monitor the patient for electrolyte balance and glucose levels during infusion.
- Special Instructions:
- Do not administer simultaneously with blood transfusions through the same set.
- Adjust the rate in patients with compromised renal or cardiac function.
Always follow institutional protocols and the specific medical orders provided for the patient. The 50ml bag is not intended for prolonged infusion therapy but rather for short-term or supplemental use.
Mode of Action 5% w/v DEXTROSE & 0.225% w/v SODIUM CHLORIDE INJECTION USP
The therapeutic effects of this combination stem from its dual components – dextrose and sodium chloride – working together to address hydration, energy supplementation, and electrolyte balance.
- Dextrose:
- Serves as a quick source of glucose for energy production.
- Is metabolized via glycolysis, supporting cellular metabolism and preventing ketosis.
- Sodium Chloride:
- Supplies sodium ions that maintain extracellular fluid volume and osmotic pressure.
- Chloride ions help maintain acid-base balance and gastric secretions.
This solution also helps prevent dehydration and electrolyte imbalances in patients unable to take oral fluids. The hypotonicity allows partial free water delivery, which is beneficial in conditions like hypernatremia or in pediatric maintenance therapy.
5% w/v DEXTROSE & 0.225% w/v SODIUM CHLORIDE INJECTION USP Interactions 5% w/v DEXTROSE & 0.225% w/v SODIUM CHLORIDE INJECTION USP
Although this IV solution is generally safe and well-tolerated, caution is required when used with certain medications and clinical conditions that may affect fluid and electrolyte balance.
- Potential Drug Interactions:
- Corticosteroids: May promote sodium and fluid retention.
- Diuretics: May increase the risk of electrolyte disturbances.
- Insulin: Enhances cellular uptake of dextrose; may cause hypoglycemia if not properly balanced.
- Cardiac Glycosides (e.g., Digoxin): Electrolyte imbalance, especially hypokalemia or hypernatremia, can potentiate toxicity.
- Other Considerations:
- Concurrent use with blood products should be avoided in the same line.
- Drugs mixed into this solution may alter its tonicity and compatibility.
Always evaluate patient medications and clinical conditions before initiating IV fluids. Laboratory monitoring is crucial for high-risk patients.
Dosage of 5% w/v DEXTROSE & 0.225% w/v SODIUM CHLORIDE INJECTION USP
The dosage of this IV solution depends on individual patient needs based on age, body weight, clinical status, and laboratory values. The 50ml plastic bag size is particularly suitable for:
- Neonatal or pediatric maintenance fluid therapy.
- Supplemental hydration in patients with restricted fluid intake.
- Dilution or carrier for other medications under strict clinical monitoring.
Typical Dosage Guidelines:
- Adults: Generally not used for primary fluid therapy; may be used for precise volume replacement or medication dilution.
- Children and Neonates: Dose calculated per body weight (e.g., mL/kg/day), and based on maintenance fluid requirements (typically 100–150 mL/kg/day in neonates).
Important Points:
- Always administer under the supervision of a healthcare provider.
- Infusion rate must be carefully adjusted based on the patient's hydration and electrolyte status.
- Do not exceed the recommended infusion rate to avoid fluid overload or electrolyte imbalance.
Possible side effects of 5% w/v DEXTROSE & 0.225% w/v SODIUM CHLORIDE INJECTION USP
Though generally well-tolerated, adverse effects can occur, particularly in sensitive populations or when administered inappropriately.
- Common Side Effects:
- Local irritation or pain at the infusion site.
- Mild swelling or redness (phlebitis).
- Serious Side Effects (rare):
- Hyperglycemia due to excessive dextrose.
- Electrolyte imbalances – particularly hyponatremia or hypernatremia.
- Fluid overload leading to edema, hypertension, or pulmonary congestion.
- Hypokalemia, especially if no potassium supplementation is provided.
- Allergic Reactions:
- Rare, but may include rash, itching, or anaphylaxis in sensitive individuals.
Prompt medical attention is necessary if serious adverse effects occur. Monitor electrolytes, fluid balance, and blood glucose regularly during therapy.
5% w/v DEXTROSE & 0.225% w/v SODIUM CHLORIDE INJECTION USP Contraindications 5% w/v DEXTROSE & 0.225% w/v SODIUM CHLORIDE INJECTION USP
This solution should not be used in certain medical conditions where fluid or electrolyte disturbances can be life-threatening.
- Absolute Contraindications:
- Known hypersensitivity to dextrose or sodium chloride.
- Severe hyperglycemia or glucose intolerance (e.g., uncontrolled diabetes).
- Severe hypernatremia or fluid overload states (e.g., pulmonary edema, congestive heart failure).
- Relative Contraindications (caution required):
- Renal impairment – risk of sodium retention and fluid overload.
- Liver disease – may impair glucose metabolism.
- Post-operative states requiring precise fluid management.
Thorough patient assessment and laboratory monitoring are essential before initiating therapy with this IV fluid.
Storage of 5% w/v DEXTROSE & 0.225% w/v SODIUM CHLORIDE INJECTION USP
Proper storage is essential to ensure sterility, stability, and safety of the product.
- Storage Conditions:
- Store at controlled room temperature: 15°C to 25°C (59°F to 77°F).
- Keep away from excessive heat, freezing, and direct sunlight.
- Handling Instructions:
- Check for leaks, discoloration, or particulate matter before use.
- Use only if the solution is clear and the container is intact.
- Do not reconnect partially used bags to avoid contamination.
- Post-Use Disposal:
- Dispose of used bags and tubing following institutional biomedical waste protocols.
- Do not reuse or resterilize the bag.
Adhering to proper storage and handling protocols helps maintain product efficacy and ensures patient safety.
5% w/v DEXTROSE & 0.225% w/v SODIUM CHLORIDE INJECTION USP features an exceptional active ingredient renowned for its potent effects, comprising Dextrose (anhydrous), Sodium chloride. This powerful formulation provides a superior solution for addressing diverse health concerns. With 50mg, 2.25mg/ml concentration and an easily manageable Infusion/Solution for, it remains a preferred option for countless individuals seeking effective treatment.
Introduction
All you need to know about 5% w/v DEXTROSE & 0.225% w/v SODIUM CHLORIDE INJECTION USP .
Welcome to Dwaey, specifically on 5% w/v DEXTROSE & 0.225% w/v SODIUM CHLORIDE INJECTION USP page.
This medicine contains an important and useful components, as it consists of Dextrose (anhydrous), Sodium chloride.
5% w/v DEXTROSE & 0.225% w/v SODIUM CHLORIDE INJECTION USP is available in the market in concentration 50mg, 2.25mg/ml and in the form of Infusion/Solution for.
QATAR PHARMA is the producer of 5% w/v DEXTROSE & 0.225% w/v SODIUM CHLORIDE INJECTION USP and it is imported from QATAR,
The most popular alternatives of 5% w/v DEXTROSE & 0.225% w/v SODIUM CHLORIDE INJECTION USP are listed downward .
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Active Substance
Dextrose (anhydrous), Sodium chloride
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Frequently Asked Questions
5% w/v DEXTROSE & 0.225% w/v SODIUM CHLORIDE INJECTION USP should be stored according to the instructions provided by QATAR PHARMA.
In general, it is recommended to store 5% w/v DEXTROSE & 0.225% w/v SODIUM CHLORIDE INJECTION USP in a cool, dry place, away from direct sunlight
and out of the reach of children.
The duration of treatment with 5% w/v DEXTROSE & 0.225% w/v SODIUM CHLORIDE INJECTION USP may vary depending on the condition being treated
and the guidance of your healthcare provider. It is important to follow the prescribed treatment
plan and continue taking 5% w/v DEXTROSE & 0.225% w/v SODIUM CHLORIDE INJECTION USP for the recommended duration, even if your symptoms improve.
If you have any concerns or questions about the duration of treatment, consult your healthcare provider.
It is important to check with your healthcare provider or read the medication label for specific
instructions regarding alcohol consumption while taking 5% w/v DEXTROSE & 0.225% w/v SODIUM CHLORIDE INJECTION USP . Some medications, including
5% w/v DEXTROSE & 0.225% w/v SODIUM CHLORIDE INJECTION USP , may have interactions with alcohol that can reduce effectiveness, increase side
effects, or pose other risks to your health. It is best to follow the guidance provided by your
healthcare professional.
If you miss a dose of 5% w/v DEXTROSE & 0.225% w/v SODIUM CHLORIDE INJECTION USP , take it as soon as you remember. However, if it is close
to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing
schedule. Do not take a double dose to make up for a missed one unless advised by your healthcare provider.
No, do not stop taking 5% w/v DEXTROSE & 0.225% w/v SODIUM CHLORIDE INJECTION USP without consulting your healthcare provider, even if your
symptoms improve. It is important to complete the full course of treatment as prescribed. Stopping
the medication prematurely may lead to a relapse or incomplete resolution of the condition. If you
have concerns about the duration of treatment, consult your healthcare provider for guidance.
It is important to consult your healthcare provider before taking 5% w/v DEXTROSE & 0.225% w/v SODIUM CHLORIDE INJECTION USP if you are
pregnant or breastfeeding. They will be able to assess the potential risks and benefits based on your
specific situation. Please note that the safety and suitability of 5% w/v DEXTROSE & 0.225% w/v SODIUM CHLORIDE INJECTION USP during pregnancy
or breastfeeding may depend on the active substance [Active Substance], concentration 50mg, 2.25mg/ml,
and the specific recommendations of QATAR PHARMA.
The effects of 5% w/v DEXTROSE & 0.225% w/v SODIUM CHLORIDE INJECTION USP on your ability to drive or operate machinery can vary depending on
the active substance [Active Substance], concentration 50mg, 2.25mg/ml, and individual factors.
Some medications may cause drowsiness, dizziness, or other side effects that can impair your judgment
or coordination. It is important to read the medication label or consult your healthcare provider to
understand any potential effects on your ability to perform tasks that require alertness.
The instructions for taking 5% w/v DEXTROSE & 0.225% w/v SODIUM CHLORIDE INJECTION USP with or without food may vary depending on the medication
and the recommendations of QATAR PHARMA. Some medications may be more effective when taken with
food to enhance absorption or reduce stomach irritation, while others may need to be taken on an empty
stomach for optimal absorption. Read the medication label or consult your healthcare provider for specific instructions.
The use of 5% w/v DEXTROSE & 0.225% w/v SODIUM CHLORIDE INJECTION USP in children or elderly individuals may depend on various factors, including
the specific medication, type Infusion/Solution for, and the recommendations of QATAR PHARMA. Some
medications may have specific dosing instructions or precautions for these age groups. Consult your
healthcare provider or read the medication label for information regarding the safe and appropriate use
of 5% w/v DEXTROSE & 0.225% w/v SODIUM CHLORIDE INJECTION USP in children or elderly individuals.
Dwaey
All medical information published on the Dwaey website aims to increase medical awareness and health education among users. However, it is not a substitute for professional medical advice. Always consult with a specialist doctor. We strongly advise against using any information or medicine found on the site without referring to your healthcare provider.
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