FIBRO-VEIN 3% Injection/Solution for

What is FIBRO-VEIN 3%

Description

FIBRO-VEIN 3% is a sterile solution for injection containing sodium tetradecyl sulfate, a synthetic surfactant used for sclerotherapy. It is formulated at a 3% concentration (30 mg/mL) and is supplied in 5 ml glass vials, typically packaged in boxes of 10.

Medical Use

This medication is primarily used in the treatment of varicose veins and venous malformations. It works by irritating the lining of blood vessels, causing them to collapse and be absorbed by the body over time.

Therapeutic Class

FIBRO-VEIN 3% belongs to the pharmacological class of sclerosing agents and is administered by healthcare professionals during sclerotherapy procedures.

Indications

• Management of small to medium varicose veins
• Treatment of reticular veins and spider veins
• Supportive care for chronic venous insufficiency

How to use FIBRO-VEIN 3%

Administration

FIBRO-VEIN 3% should be injected only by trained healthcare providers with expertise in venous anatomy and sclerosing procedures.

Procedure Steps

• Clean the injection area thoroughly with an antiseptic solution.
• Inject the solution directly into the affected vein using a fine needle.
• Apply gentle compression to the treated area immediately after injection.
• Monitor the patient closely for any immediate adverse reactions.

Post-Treatment Care

Patients are generally advised to wear compression stockings for several days following the procedure. Physical activity should be minimized for at least 24–48 hours to reduce complications.

Mode of Action FIBRO-VEIN 3%

Mechanism

Sodium tetradecyl sulfate works by damaging the endothelium (inner lining) of the vein. This induces inflammation and eventually leads to the formation of fibrotic tissue that seals the vein shut.

Physiological Effects

Once occluded, the treated vein is no longer part of the venous return system and is naturally absorbed by the body. Blood flow is redirected to healthier surrounding veins, improving overall circulation.

Expected Outcome

Properly administered, the treatment eliminates dysfunctional veins, relieves symptoms like aching or swelling, and improves cosmetic appearance.

FIBRO-VEIN 3% Interactions FIBRO-VEIN 3%

General Safety

FIBRO-VEIN 3% has minimal systemic absorption, but interactions can still occur, especially with medications that affect blood clotting.

Drugs to Use with Caution

• Anticoagulants: May increase the risk of bleeding post-injection (e.g., warfarin, rivaroxaban).
• Oral contraceptives: Combined with sclerotherapy, they may increase thromboembolic risks.
• NSAIDs: May mask inflammation or pain at the injection site.

Patient Guidance

Inform your physician of all medications, including supplements or herbal treatments, before undergoing sclerotherapy.

Dosage of FIBRO-VEIN 3%

Typical Dose

The dose depends on the size and number of veins to be treated. Usually, 0.1–1.0 mL per injection site is used.

Maximum Volume

In a single session, up to 10 mL of solution may be administered, distributed across multiple injection sites.

Injection Frequency

Treatments are usually spaced 4 to 6 weeks apart, and multiple sessions may be needed depending on the clinical objective.

Possible side effects of FIBRO-VEIN 3%

Common Side Effects

• Mild pain or burning at the injection site
• Localized swelling or redness
• Temporary skin discoloration (hyperpigmentation)

Uncommon but Serious Reactions

• Allergic reactions, including anaphylaxis
• Superficial thrombophlebitis (vein inflammation)
• Deep vein thrombosis or pulmonary embolism
• Tissue necrosis due to extravasation

Monitoring Advice

Patients should report unusual pain, swelling, or respiratory difficulty immediately. Emergency care may be required in cases of severe reaction.

FIBRO-VEIN 3% Contraindications FIBRO-VEIN 3%

Do Not Use In:

• Patients with known hypersensitivity to sodium tetradecyl sulfate
• People with acute thrombophlebitis or DVT
• Patients with severe peripheral arterial disease
• Pregnant or breastfeeding women (unless deemed essential)
• Patients who are bedridden or unable to ambulate

Use with Caution:

In those with poorly controlled diabetes, hypertension, or thyroid dysfunction, treatment should proceed under strict supervision.

Storage of FIBRO-VEIN 3%

Storage Conditions

• Store at 2°C to 25°C (36°F to 77°F)
• Protect from light by keeping in original packaging
• Do not freeze

Stability

Ensure the product is used before the expiration date printed on the vial. Do not use if particulate matter or discoloration is observed.

Disposal

Dispose of unused portions and empty containers according to local medical waste regulations.