What is 3.33% w/v DEXTROSE & 0.3% w/v SODIUM CHLORIDE INJECTION USP
3.33% w/v Dextrose & 0.3% w/v Sodium Chloride Injection USP is a sterile, non-pyrogenic solution used for intravenous administration. It contains two essential components:
- Dextrose (as monohydrate) – 3.33% w/v: A simple sugar that provides a source of energy and supports fluid and electrolyte balance.
- Sodium chloride – 0.3% w/v: Common salt that helps replenish lost sodium and maintain osmotic equilibrium.
This solution is primarily indicated for patients needing hydration, mild caloric supplementation, and electrolyte replenishment. It is often used in clinical settings such as hospitals for patients who are unable to maintain adequate oral intake.
This infusion is particularly beneficial in treating:
- Dehydration with mild electrolyte loss
- Post-operative fluid maintenance
- Patients with low sodium levels (hyponatremia)
The formulation is packed in a 500ml plastic bag and is administered via intravenous infusion under medical supervision.
How to use 3.33% w/v DEXTROSE & 0.3% w/v SODIUM CHLORIDE INJECTION USP
This medication must be administered by a healthcare professional in a controlled medical environment. Usage involves the following guidelines:
- Route of Administration: Intravenous infusion (IV drip)
- Dosage: Depends on the patient’s clinical condition, age, weight, and electrolyte balance. A physician will determine the exact rate and volume.
- Infusion Rate: Should be adjusted to the patient’s fluid and electrolyte needs. Slow infusion is recommended to avoid fluid overload.
Prior to administration:
- Inspect the solution for clarity and absence of particulate matter or discoloration.
- Ensure the bag is not leaking and that the seal is intact.
- Use only if the solution is clear and the container is undamaged.
The infusion is typically connected to a sterile IV set, and the rate is regulated using an infusion pump or manual drip counter. Patients should be monitored throughout the infusion for signs of electrolyte imbalance or fluid overload.
Mode of Action 3.33% w/v DEXTROSE & 0.3% w/v SODIUM CHLORIDE INJECTION USP
The therapeutic effects of this solution stem from its two active ingredients:
- Dextrose: Once administered, dextrose is rapidly metabolized to carbon dioxide and water, providing a quick source of energy. It also spares body proteins and helps maintain liver glycogen stores during fasting or catabolic states.
- Sodium Chloride: This replenishes extracellular sodium levels and contributes to osmotic balance. Sodium is vital for nerve transmission, muscle contraction, and regulation of blood pressure and blood volume.
Together, these components support:
- Maintenance of fluid homeostasis
- Correction of mild hyponatremia
- Caloric support in malnourished or dehydrated patients
By combining glucose and saline, the infusion offers dual support in restoring both energy and electrolyte balance in acute and maintenance therapy.
3.33% w/v DEXTROSE & 0.3% w/v SODIUM CHLORIDE INJECTION USP Interactions 3.33% w/v DEXTROSE & 0.3% w/v SODIUM CHLORIDE INJECTION USP
Although generally safe under medical supervision, this infusion may interact with the following:
- Corticosteroids (e.g., hydrocortisone): Can increase sodium retention and may exacerbate fluid overload.
- Diuretics: Loop or thiazide diuretics can alter electrolyte balance, especially potassium and sodium levels.
- Insulin: May be required in diabetic patients to manage glucose from dextrose; insulin also facilitates the cellular uptake of glucose and potassium.
- ACE inhibitors and ARBs: These can alter renal sodium handling and may increase the risk of electrolyte imbalance.
Patients should be monitored for:
- Serum glucose fluctuations in diabetic individuals
- Electrolyte levels (especially sodium and potassium)
- Fluid overload in cardiac or renal impairment
Dosage of 3.33% w/v DEXTROSE & 0.3% w/v SODIUM CHLORIDE INJECTION USP
The dosage and rate of infusion depend on individual patient needs and clinical judgment. However, general dosing guidelines include:
- Adults: 500–1000 ml/day depending on fluid and electrolyte requirements.
- Children: Dosing is weight-based; typically 20–100 ml/kg/day under close monitoring.
- Infusion Rate: Should not exceed the patient’s renal excretion capacity to avoid fluid overload.
Monitoring requirements during administration:
- Blood glucose (especially in diabetics)
- Serum electrolytes and osmolality
- Fluid input/output and signs of overhydration
Always administer using aseptic techniques. Do not mix with incompatible solutions unless under expert supervision.
Possible side effects of 3.33% w/v DEXTROSE & 0.3% w/v SODIUM CHLORIDE INJECTION USP
This formulation is generally well-tolerated, but some adverse effects may occur:
- Hyperglycemia: Especially in diabetic or insulin-resistant patients due to the dextrose content.
- Fluid overload: Signs include peripheral edema, pulmonary edema, and hypertension.
- Electrolyte imbalance: Overcorrection or improper monitoring can lead to hypo/hypernatremia or hypokalemia.
- Phlebitis: Inflammation of the vein at the infusion site, especially with prolonged use.
- Hypersensitivity reactions: Rare, but may include rash, itching, or fever.
Patients with pre-existing cardiac, hepatic, or renal impairments are more susceptible to these side effects and require close monitoring.
3.33% w/v DEXTROSE & 0.3% w/v SODIUM CHLORIDE INJECTION USP Contraindications 3.33% w/v DEXTROSE & 0.3% w/v SODIUM CHLORIDE INJECTION USP
This solution should not be used in the following conditions:
- Severe hypernatremia: May worsen sodium overload.
- Hyperglycemia or diabetic coma (untreated): Dextrose can exacerbate elevated blood glucose levels.
- Congestive heart failure: Risk of fluid overload and pulmonary edema.
- Renal failure with oliguria or anuria: Inability to excrete fluids and electrolytes may lead to toxicity.
- Uncontrolled edema or fluid retention disorders
Use with caution in:
- Patients on corticosteroids or other drugs affecting fluid balance
- Diabetic patients requiring glucose monitoring and insulin adjustment
Storage of 3.33% w/v DEXTROSE & 0.3% w/v SODIUM CHLORIDE INJECTION USP
Proper storage ensures the safety and effectiveness of the solution:
- Storage Temperature: Store below 25°C. Do not freeze.
- Light Protection: Keep in the original packaging to protect from light if required by the manufacturer.
- Integrity Check: Discard the bag if it shows signs of leakage, damage, or discoloration.
- Single Use: Once opened, the solution should be used immediately. Discard any unused portion to prevent contamination.
Keep out of reach of children and dispose of used containers safely, in accordance with local guidelines for medical waste.
3.33% w/v DEXTROSE & 0.3% w/v SODIUM CHLORIDE INJECTION USP features an exceptional active ingredient renowned for its potent effects, comprising Dextrose (as monohydrate), Sodium chloride. This powerful formulation provides a superior solution for addressing diverse health concerns. With 33mg, 3mg/ml concentration and an easily manageable Infusion/Solution for, it remains a preferred option for countless individuals seeking effective treatment.
Introduction
All you need to know about 3.33% w/v DEXTROSE & 0.3% w/v SODIUM CHLORIDE INJECTION USP .
Welcome to Dwaey, specifically on 3.33% w/v DEXTROSE & 0.3% w/v SODIUM CHLORIDE INJECTION USP page.
This medicine contains an important and useful components, as it consists of Dextrose (as monohydrate), Sodium chloride.
3.33% w/v DEXTROSE & 0.3% w/v SODIUM CHLORIDE INJECTION USP is available in the market in concentration 33mg, 3mg/ml and in the form of Infusion/Solution for.
WELLPHARMA MEDICAL SOLUTIONS LLC is the producer of 3.33% w/v DEXTROSE & 0.3% w/v SODIUM CHLORIDE INJECTION USP and it is imported from UAE,
The most popular alternatives of 3.33% w/v DEXTROSE & 0.3% w/v SODIUM CHLORIDE INJECTION USP are listed downward .
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Active Substance
Dextrose (as monohydrate), Sodium chloride
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Size
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Indications
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Type
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Company
WELLPHARMA MEDICAL SOLUTIONS LLC
Frequently Asked Questions
3.33% w/v DEXTROSE & 0.3% w/v SODIUM CHLORIDE INJECTION USP should be stored according to the instructions provided by WELLPHARMA MEDICAL SOLUTIONS LLC.
In general, it is recommended to store 3.33% w/v DEXTROSE & 0.3% w/v SODIUM CHLORIDE INJECTION USP in a cool, dry place, away from direct sunlight
and out of the reach of children.
The duration of treatment with 3.33% w/v DEXTROSE & 0.3% w/v SODIUM CHLORIDE INJECTION USP may vary depending on the condition being treated
and the guidance of your healthcare provider. It is important to follow the prescribed treatment
plan and continue taking 3.33% w/v DEXTROSE & 0.3% w/v SODIUM CHLORIDE INJECTION USP for the recommended duration, even if your symptoms improve.
If you have any concerns or questions about the duration of treatment, consult your healthcare provider.
It is important to check with your healthcare provider or read the medication label for specific
instructions regarding alcohol consumption while taking 3.33% w/v DEXTROSE & 0.3% w/v SODIUM CHLORIDE INJECTION USP . Some medications, including
3.33% w/v DEXTROSE & 0.3% w/v SODIUM CHLORIDE INJECTION USP , may have interactions with alcohol that can reduce effectiveness, increase side
effects, or pose other risks to your health. It is best to follow the guidance provided by your
healthcare professional.
If you miss a dose of 3.33% w/v DEXTROSE & 0.3% w/v SODIUM CHLORIDE INJECTION USP , take it as soon as you remember. However, if it is close
to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing
schedule. Do not take a double dose to make up for a missed one unless advised by your healthcare provider.
No, do not stop taking 3.33% w/v DEXTROSE & 0.3% w/v SODIUM CHLORIDE INJECTION USP without consulting your healthcare provider, even if your
symptoms improve. It is important to complete the full course of treatment as prescribed. Stopping
the medication prematurely may lead to a relapse or incomplete resolution of the condition. If you
have concerns about the duration of treatment, consult your healthcare provider for guidance.
It is important to consult your healthcare provider before taking 3.33% w/v DEXTROSE & 0.3% w/v SODIUM CHLORIDE INJECTION USP if you are
pregnant or breastfeeding. They will be able to assess the potential risks and benefits based on your
specific situation. Please note that the safety and suitability of 3.33% w/v DEXTROSE & 0.3% w/v SODIUM CHLORIDE INJECTION USP during pregnancy
or breastfeeding may depend on the active substance [Active Substance], concentration 33mg, 3mg/ml,
and the specific recommendations of WELLPHARMA MEDICAL SOLUTIONS LLC.
The effects of 3.33% w/v DEXTROSE & 0.3% w/v SODIUM CHLORIDE INJECTION USP on your ability to drive or operate machinery can vary depending on
the active substance [Active Substance], concentration 33mg, 3mg/ml, and individual factors.
Some medications may cause drowsiness, dizziness, or other side effects that can impair your judgment
or coordination. It is important to read the medication label or consult your healthcare provider to
understand any potential effects on your ability to perform tasks that require alertness.
The instructions for taking 3.33% w/v DEXTROSE & 0.3% w/v SODIUM CHLORIDE INJECTION USP with or without food may vary depending on the medication
and the recommendations of WELLPHARMA MEDICAL SOLUTIONS LLC. Some medications may be more effective when taken with
food to enhance absorption or reduce stomach irritation, while others may need to be taken on an empty
stomach for optimal absorption. Read the medication label or consult your healthcare provider for specific instructions.
The use of 3.33% w/v DEXTROSE & 0.3% w/v SODIUM CHLORIDE INJECTION USP in children or elderly individuals may depend on various factors, including
the specific medication, type Infusion/Solution for, and the recommendations of WELLPHARMA MEDICAL SOLUTIONS LLC. Some
medications may have specific dosing instructions or precautions for these age groups. Consult your
healthcare provider or read the medication label for information regarding the safe and appropriate use
of 3.33% w/v DEXTROSE & 0.3% w/v SODIUM CHLORIDE INJECTION USP in children or elderly individuals.
Dwaey
All medical information published on the Dwaey website aims to increase medical awareness and health education among users. However, it is not a substitute for professional medical advice. Always consult with a specialist doctor. We strongly advise against using any information or medicine found on the site without referring to your healthcare provider.
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