3 V Injection/Solution for

What is 3 V

3 V is a sterile injectable solution that contains a combination of three essential B-complex vitamins: Vitamin B1 (Thiamine), Vitamin B6 (Pyridoxine), and Vitamin B12 (Cyanocobalamin). It is presented in 3ml ampoules and offered in bulk packaging of 50 ampoules, typically for clinical or hospital use where multiple patients require treatment or long-term supplementation.

This vitamin blend is widely used for:

• Treatment of vitamin B-complex deficiencies
• Supportive therapy in neuropathies, such as peripheral neuritis and diabetic neuropathy
• Alcohol-related neurological damage
• Post-surgical recovery and chronic fatigue syndromes
• Supplementation in malnourished individuals or those with increased metabolic demand

The combination of these three vitamins supports nerve health, red blood cell production, metabolic function, and general neurological wellbeing.

How to use 3 V

3 V should only be administered under medical supervision via intramuscular injection. Proper technique and dosing are critical to avoid local tissue reactions and to ensure therapeutic benefit.

• Ensure the ampoule is clear and free from particulate matter before use.
• Use a sterile syringe and needle for each administration.
• Inject deeply into a large muscle, preferably the gluteal muscle.
• Alternate injection sites if therapy is prolonged to avoid irritation or abscess formation.
• Dispose of used needles and ampoules safely in a sharps container.

In clinical settings, ampoules from the bulk pack can be used across multiple patients following strict aseptic techniques and patient-specific labeling protocols.

Mode of Action 3 V

The combined action of B1, B6, and B12 contributes to energy metabolism, neural integrity, and hematopoiesis:

• Vitamin B1 (Thiamine) is essential for ATP production and acts as a coenzyme in carbohydrate metabolism. It supports nervous system and cardiovascular function.
• Vitamin B6 (Pyridoxine) functions as a coenzyme in amino acid metabolism, neurotransmitter synthesis (e.g., serotonin, dopamine), and immune system regulation.
• Vitamin B12 (Cyanocobalamin) is crucial for DNA synthesis, red blood cell formation, and proper neurological function.

Together, they restore deficiencies, improve nerve conduction, alleviate neuropathic pain, and enhance energy levels in deficient patients.

3 V Interactions 3 V

Some drug interactions can alter the absorption or effectiveness of the vitamins in 3 V:

• Vitamin B6 (Pyridoxine):
  • Reduces the effectiveness of Levodopa unless used with a DOPA decarboxylase inhibitor
  • Can interact with phenytoin and phenobarbital, possibly decreasing their plasma levels
• Vitamin B12 (Cyanocobalamin):
  • Absorption reduced by long-term use of proton pump inhibitors (PPIs), metformin, and certain antibiotics like chloramphenicol
• Vitamin B1 (Thiamine):
  • Its bioavailability can be reduced by chronic alcohol intake or diuretics like furosemide

Always review the patient’s full medication list and consult a pharmacist if needed, especially in patients on long-term therapies or multiple medications.

Dosage of 3 V

Dosage should be individualized based on the patient’s condition, age, clinical need, and the presence of any underlying disease. A typical adult dosage recommendation is:

• 3ml intramuscularly once daily for acute deficiency states or severe neuropathy
• 3ml every other day or 2–3 times weekly for maintenance or chronic therapy
• Duration of therapy varies—generally 1–2 weeks for acute supplementation, and longer courses (4–6 weeks or more) in chronic conditions

For pediatric use, elderly patients, or those with renal/hepatic impairment, dosage adjustments may be required. Healthcare professionals should monitor for therapeutic response and any adverse effects during the treatment course.

Possible side effects of 3 V

3 V is generally well tolerated, but side effects may occur in some patients:

• Common effects:
  • Pain, redness, or swelling at the injection site
  • Nausea or stomach discomfort
  • Transient flushing or warmth
• Less common but serious reactions:
  • Allergic reactions such as rash, itching, or urticaria
  • Anaphylaxis (rare, especially with Vitamin B12)
  • Neuropathy or nerve irritation with excessive Vitamin B6 dosing over time

Discontinue the injection and seek immediate medical care if signs of allergy, breathing difficulty, or severe neurological symptoms develop. Routine follow-up is advised in long-term users.

3 V Contraindications 3 V

Use of 3 V is contraindicated in the following cases:

• Hypersensitivity to Thiamine, Pyridoxine, Cyanocobalamin, or any excipients in the formulation
• Leber’s hereditary optic neuropathy: Vitamin B12 may worsen optic nerve damage
• Patients with a history of allergic reactions to cobalamin injections
• Severe liver disease, unless used under strict medical supervision

Caution is advised in patients with renal impairment, those on polypharmacy, or those prone to allergic reactions.

Storage of 3 V

To preserve its efficacy and safety, 3 V should be stored under proper conditions:

• Keep at a controlled room temperature of 15°C to 25°C (59°F to 77°F)
• Protect from light—store in the original carton until the moment of use
• Do not freeze. If frozen, the contents should be discarded
• Discard ampoules if the solution is discolored or contains particulates
• Keep out of reach of children and pets

In hospital or clinic settings, ensure the bulk pack is stored in secure medical storage with tracking for inventory and expiration dates.