3 V Injection/Solution for

What is 3 V

3 V is a combination injectable solution containing three essential B vitamins: Vitamin B1 (Thiamine), Vitamin B6 (Pyridoxine), and Vitamin B12 (Cyanocobalamin). It is presented in a 3ml ampoule and typically packaged in a set of three ampoules. This formulation is intended for intramuscular administration and is used to treat or prevent deficiencies of these vital vitamins.

• Vitamin B1 (Thiamine) supports carbohydrate metabolism and nerve function.
• Vitamin B6 (Pyridoxine) plays a role in amino acid metabolism, neurotransmitter synthesis, and immune function.
• Vitamin B12 (Cyanocobalamin) is essential for red blood cell formation, neurological function, and DNA synthesis.

This combination is commonly prescribed in cases of:

• Peripheral neuropathy
• Alcoholism-related vitamin deficiency
• Post-surgical recovery
• Chronic fatigue and anemia associated with B-vitamin deficiencies

How to use 3 V

3 V is administered via intramuscular injection only. It must be given by a healthcare professional, typically into the gluteal muscle. Correct administration technique and adherence to dosage schedules are essential for therapeutic success.

• Inspect the ampoule visually before use. Do not use if it appears cloudy or has particulate matter.
• Use aseptic techniques to withdraw and inject the solution.
• Ensure the entire 3ml is administered in a single injection unless otherwise advised by a physician.

Do not self-administer unless instructed and trained by a healthcare provider. Complete the full course even if symptoms improve early, especially in cases of neurological symptoms.

Mode of Action 3 V

The therapeutic effects of 3 V are due to the synergistic actions of its components:

• Thiamine (B1) acts as a coenzyme in carbohydrate metabolism and is crucial for neural function and energy production.
• Pyridoxine (B6) serves as a coenzyme for numerous enzymatic reactions involved in amino acid and neurotransmitter metabolism.
• Cyanocobalamin (B12) is required for proper red blood cell formation and maintenance of myelin in the nervous system.

Together, these vitamins help restore nerve function, improve energy metabolism, and reverse clinical symptoms associated with deficiency such as fatigue, neuropathy, and anemia.

3 V Interactions 3 V

While generally safe, the components of 3 V can interact with certain medications:

• Vitamin B6 may decrease the efficacy of:
  • Levodopa (unless combined with a dopa decarboxylase inhibitor)
  • Phenobarbital and phenytoin (by altering metabolism)
• Vitamin B12 absorption may be reduced by:
  • Proton pump inhibitors (e.g., omeprazole)
  • Metformin
  • Chloramphenicol
• Vitamin B1 may be degraded by alcohol and some diuretics like furosemide, reducing its effectiveness.

Always inform your healthcare provider about all medications you are currently taking, including over-the-counter drugs and supplements, to avoid interactions.

Dosage of 3 V

Dosage of 3 V should always be determined by a healthcare provider based on the patient's clinical condition, age, severity of symptoms, and nutritional status. A general adult dosing guideline is:

• Intramuscular Injection: 3ml once daily or every other day for a period of 1 to 2 weeks.
• In maintenance therapy, the frequency may be reduced to once weekly or as needed.

Children and elderly patients may require adjusted doses. Do not exceed recommended dosing without medical advice. Periodic monitoring of vitamin levels may be advised during prolonged therapy.

Possible side effects of 3 V

Most patients tolerate 3 V well, but some may experience side effects, especially if hypersensitive or when high doses are administered.

• Common mild effects:
  • Pain or redness at the injection site
  • Flushing or warmth sensation
  • Nausea
  • Headache
• Less common or serious effects:
  • Hypersensitivity reactions (rash, itching)
  • Dyspnea or tightness in chest (rare anaphylaxis with B12)
  • Numbness or tingling with prolonged B6 overuse

Seek immediate medical attention in case of allergic reactions or neurological symptoms.

3 V Contraindications 3 V

3 V should not be used in the following situations:

• Known hypersensitivity to thiamine, pyridoxine, cyanocobalamin, or any component of the formulation.
• Leber’s disease (hereditary optic neuropathy): B12 may accelerate optic nerve atrophy.
• Severe hepatic impairment unless deemed necessary and monitored closely.
• Neonates and infants unless prescribed and supervised by a pediatric specialist.

Caution is advised in patients with renal insufficiency or those receiving other vitamin supplements to avoid cumulative overdose.

Storage of 3 V

Proper storage is essential to maintain the stability and efficacy of the product.

• Store at controlled room temperature: 15°C to 25°C (59°F to 77°F).
• Protect from light. Keep the ampoules in the original packaging until use.
• Do not freeze the solution. Discard if frozen or if the contents appear discolored or contain particles.
• Keep out of reach of children and pets.
• Check expiration date before use. Do not use expired ampoules.

Proper storage ensures the vitamin content remains potent and safe for administration during the entire shelf life.