What is 25% w/v DEXTROSE INJECTION USP
25% w/v Dextrose Injection USP is a sterile, hypertonic intravenous solution composed of 25 grams of anhydrous dextrose dissolved in 100 milliliters of sterile water for injection, supplied in a 500ml plastic bag. It is primarily used to provide a concentrated source of glucose, which serves as a key energy substrate in clinical settings.
- Purpose: It is indicated for patients who require rapid correction of hypoglycemia, nutritional supplementation when oral intake is inadequate or impossible, and as part of fluid and electrolyte management in various medical conditions.
- Composition: Contains anhydrous dextrose, a simple sugar that is metabolized by the body to provide immediate energy.
- Formulation: The solution is clear, colorless, and free of visible particulates, making it safe for intravenous administration.
- Clinical Use: Used in hospitals for parenteral nutrition, treatment of dehydration, and as a diluent or vehicle for compatible intravenous medications.
- Indications: Correction of hypoglycemia, maintenance of blood glucose levels during fasting, provision of calories for metabolic needs, and treatment of certain fluid imbalances.
How to use 25% w/v DEXTROSE INJECTION USP
Administration of 25% Dextrose Injection requires careful clinical judgment and monitoring to ensure safety and efficacy.
- Route: Administered strictly via intravenous infusion. Do not use intramuscularly or subcutaneously to avoid tissue irritation and necrosis.
- Preparation: Inspect the solution visually to ensure it is clear and free of particles. Confirm compatibility if mixing with other intravenous drugs.
- Infusion Rate: Adjust the infusion rate based on the patient's condition, blood glucose levels, and fluid status to avoid complications such as hyperglycemia or fluid overload.
- Monitoring: Continuously monitor blood glucose, electrolytes, and overall fluid balance during administration.
- Dosing: Dosage should be individualized depending on patient age, weight, clinical condition, and specific therapeutic needs.
- Emergency Use: For acute hypoglycemia, bolus intravenous administration under strict medical supervision is appropriate.
Mode of Action 25% w/v DEXTROSE INJECTION USP
The pharmacological effect of 25% Dextrose Injection is based on its provision of glucose, an essential energy substrate.
- Energy Source: Dextrose is rapidly absorbed into the bloodstream and taken up by cells, where it undergoes glycolysis to produce ATP, the primary energy currency of cells.
- Blood Glucose Regulation: The infusion elevates blood glucose levels, correcting hypoglycemia and providing energy to metabolically active tissues such as the brain and muscles.
- Osmotic Effect: Being hypertonic, it draws fluid from intracellular compartments into the vascular system, aiding in rehydration and maintenance of circulatory volume.
- Supportive Role: Helps maintain caloric intake in patients who cannot consume adequate nutrition orally or enterally.
25% w/v DEXTROSE INJECTION USP Interactions 25% w/v DEXTROSE INJECTION USP
Dextrose injection can interact with various medications, necessitating careful monitoring.
- Insulin and Oral Hypoglycemics: These drugs lower blood glucose, so concurrent administration with dextrose requires dose adjustments to avoid hypo- or hyperglycemia.
- Diuretics: May exacerbate electrolyte imbalances, especially potassium disturbances when used alongside dextrose solutions.
- Warfarin: Hyperglycemia may alter the metabolism of warfarin, potentially affecting anticoagulation control.
- Corticosteroids and Catecholamines: Both may raise blood glucose levels, increasing the risk of hyperglycemia when combined with dextrose infusions.
- Intravenous Drugs: Always verify compatibility before mixing other drugs with dextrose solutions to avoid precipitation or inactivation.
Dosage of 25% w/v DEXTROSE INJECTION USP
The dosage of 25% Dextrose Injection should be individualized based on the patient's clinical needs, age, weight, and metabolic status.
- Adults: Maintenance doses generally range from 100 to 250 ml administered over several hours, depending on caloric and fluid requirements.
- Emergency Hypoglycemia: Rapid intravenous bolus doses of 25 to 50 ml may be administered under close supervision.
- Children: Dose calculations are typically weight-based and carefully titrated to avoid rapid fluctuations in blood glucose.
- Adjustment: Dosage must be modified according to blood glucose measurements, electrolyte status, and renal or cardiac function.
- Parenteral Nutrition: Often combined with amino acids and lipids for comprehensive nutritional support in critically ill patients.
Possible side effects of 25% w/v DEXTROSE INJECTION USP
While generally well tolerated, 25% Dextrose Injection may cause some adverse effects, especially if improperly administered.
- Local Reactions: Pain, irritation, or thrombophlebitis at the infusion site due to hyperosmolarity.
- Hyperglycemia: Excessive infusion can cause high blood sugar, leading to symptoms such as thirst, increased urination, headache, and in severe cases, diabetic ketoacidosis.
- Fluid Overload: Risk of pulmonary edema or heart failure in susceptible individuals if administered too rapidly or in excess.
- Electrolyte Imbalances: Shifts in potassium and sodium levels can cause arrhythmias or neurological symptoms.
- Allergic Reactions: Rare but may include rash, itching, or anaphylaxis.
- Other: Nausea, dizziness, or headache may occur in some patients.
25% w/v DEXTROSE INJECTION USP Contraindications 25% w/v DEXTROSE INJECTION USP
Administration of this solution is contraindicated or should be used with caution in the following situations:
- Uncontrolled Hyperglycemia: Patients with markedly elevated blood glucose or diabetic ketoacidosis should not receive hypertonic dextrose.
- Severe Dehydration: Without prior electrolyte correction, hypertonic solutions may worsen imbalance.
- Allergy: Known hypersensitivity to dextrose or any component of the formulation.
- Intracranial Hemorrhage: Risk of increased intracranial pressure due to osmotic effects.
- Severe Renal or Cardiac Disease: Risk of fluid overload and electrolyte disturbances.
Storage of 25% w/v DEXTROSE INJECTION USP
Proper storage ensures the integrity and sterility of the dextrose solution:
- Temperature: Store at controlled room temperature between 20°C and 25°C (68°F to 77°F). Avoid freezing.
- Protection: Keep in original packaging to protect from light and contamination.
- Handling: Do not shake the bag vigorously to prevent foaming and contamination.
- Inspection: Before use, inspect for cloudiness, discoloration, or particulate matter. Do not use if these are present.
- Expiration: Use before the expiry date indicated on the packaging.
- Environment: Store in a clean, dry place away from incompatible substances and extreme temperatures.
25% w/v DEXTROSE INJECTION USP features an exceptional active ingredient renowned for its potent effects, comprising Dextrose (anhydrous). This powerful formulation provides a superior solution for addressing diverse health concerns. With 250mg/ml concentration and an easily manageable Infusion/Solution for, it remains a preferred option for countless individuals seeking effective treatment.
Introduction
All you need to know about 25% w/v DEXTROSE INJECTION USP .
Welcome to Dwaey, specifically on 25% w/v DEXTROSE INJECTION USP page.
This medicine contains an important and useful components, as it consists of Dextrose (anhydrous).
25% w/v DEXTROSE INJECTION USP is available in the market in concentration 250mg/ml and in the form of Infusion/Solution for.
QATAR PHARMA is the producer of 25% w/v DEXTROSE INJECTION USP and it is imported from QATAR,
The most popular alternatives of 25% w/v DEXTROSE INJECTION USP are listed downward .
-
Active Substance
-
Size
-
Indications
-
Type
-
Company
Frequently Asked Questions
25% w/v DEXTROSE INJECTION USP should be stored according to the instructions provided by QATAR PHARMA.
In general, it is recommended to store 25% w/v DEXTROSE INJECTION USP in a cool, dry place, away from direct sunlight
and out of the reach of children.
The duration of treatment with 25% w/v DEXTROSE INJECTION USP may vary depending on the condition being treated
and the guidance of your healthcare provider. It is important to follow the prescribed treatment
plan and continue taking 25% w/v DEXTROSE INJECTION USP for the recommended duration, even if your symptoms improve.
If you have any concerns or questions about the duration of treatment, consult your healthcare provider.
It is important to check with your healthcare provider or read the medication label for specific
instructions regarding alcohol consumption while taking 25% w/v DEXTROSE INJECTION USP. Some medications, including
25% w/v DEXTROSE INJECTION USP, may have interactions with alcohol that can reduce effectiveness, increase side
effects, or pose other risks to your health. It is best to follow the guidance provided by your
healthcare professional.
If you miss a dose of 25% w/v DEXTROSE INJECTION USP, take it as soon as you remember. However, if it is close
to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing
schedule. Do not take a double dose to make up for a missed one unless advised by your healthcare provider.
No, do not stop taking 25% w/v DEXTROSE INJECTION USP without consulting your healthcare provider, even if your
symptoms improve. It is important to complete the full course of treatment as prescribed. Stopping
the medication prematurely may lead to a relapse or incomplete resolution of the condition. If you
have concerns about the duration of treatment, consult your healthcare provider for guidance.
It is important to consult your healthcare provider before taking 25% w/v DEXTROSE INJECTION USP if you are
pregnant or breastfeeding. They will be able to assess the potential risks and benefits based on your
specific situation. Please note that the safety and suitability of 25% w/v DEXTROSE INJECTION USP during pregnancy
or breastfeeding may depend on the active substance [Active Substance], concentration 250mg/ml,
and the specific recommendations of QATAR PHARMA.
The effects of 25% w/v DEXTROSE INJECTION USP on your ability to drive or operate machinery can vary depending on
the active substance [Active Substance], concentration 250mg/ml, and individual factors.
Some medications may cause drowsiness, dizziness, or other side effects that can impair your judgment
or coordination. It is important to read the medication label or consult your healthcare provider to
understand any potential effects on your ability to perform tasks that require alertness.
The instructions for taking 25% w/v DEXTROSE INJECTION USP with or without food may vary depending on the medication
and the recommendations of QATAR PHARMA. Some medications may be more effective when taken with
food to enhance absorption or reduce stomach irritation, while others may need to be taken on an empty
stomach for optimal absorption. Read the medication label or consult your healthcare provider for specific instructions.
The use of 25% w/v DEXTROSE INJECTION USP in children or elderly individuals may depend on various factors, including
the specific medication, type Infusion/Solution for, and the recommendations of QATAR PHARMA. Some
medications may have specific dosing instructions or precautions for these age groups. Consult your
healthcare provider or read the medication label for information regarding the safe and appropriate use
of 25% w/v DEXTROSE INJECTION USP in children or elderly individuals.
Dwaey
All medical information published on the Dwaey website aims to increase medical awareness and health education among users. However, it is not a substitute for professional medical advice. Always consult with a specialist doctor. We strongly advise against using any information or medicine found on the site without referring to your healthcare provider.
Related Products
0 Comments