What is 25% w/v DEXTROSE INJECTION USP
25% w/v Dextrose Injection USP is a sterile, hypertonic intravenous solution composed of 25 grams of anhydrous dextrose per 100 milliliters of water. It is supplied in a 250ml plastic bag and is intended for intravenous infusion.
- Purpose: This solution serves as a concentrated source of glucose, providing essential calories and fluids to patients who are unable to eat or drink adequately, or who need rapid correction of hypoglycemia or dehydration.
- Composition: The active ingredient is anhydrous dextrose, a simple sugar that acts as an immediate energy source for the body’s cells.
- Clinical Use: It is commonly used in hospitals and emergency settings for patients requiring nutritional supplementation, treatment of low blood sugar, or as part of intravenous therapy for fluid and electrolyte balance.
- Form: The solution is clear, colorless, and free from particles, ensuring safe administration via intravenous infusion.
- Indications: Treatment of hypoglycemia, intravenous calorie replacement, correction of dehydration, and as a diluent for compatible intravenous drugs.
How to use 25% w/v DEXTROSE INJECTION USP
Proper administration of 25% Dextrose Injection is critical for patient safety and therapeutic effectiveness.
- Route of Administration: Intravenous infusion only. It should never be given intramuscularly or subcutaneously due to risk of tissue irritation and damage.
- Preparation: Before use, inspect the bag for clarity and absence of particles. Confirm compatibility if mixing with other medications.
- Infusion Rate: The rate should be tailored to the patient’s clinical condition, avoiding rapid infusion to prevent hyperglycemia or fluid overload.
- Monitoring: Regular monitoring of blood glucose, electrolytes, and fluid balance is essential during infusion.
- Dosing Adjustments: Modify dosage according to patient response, underlying medical conditions, and lab results.
- Use in Emergencies: For acute hypoglycemia, rapid intravenous administration under supervision is appropriate.
Mode of Action 25% w/v DEXTROSE INJECTION USP
The therapeutic effects of 25% Dextrose Injection arise primarily from its role as a glucose source in the body.
- Energy Production: Dextrose is rapidly absorbed into the bloodstream, supplying glucose, which is metabolized via glycolysis and the citric acid cycle to generate ATP, the main cellular energy molecule.
- Blood Sugar Regulation: It promptly increases blood glucose levels, helping to alleviate hypoglycemia and maintain energy supply in fasting or ill patients.
- Osmotic Properties: As a hypertonic solution, it draws water from intracellular to extracellular spaces, assisting in rehydration and maintaining plasma volume.
- Supportive Nutrition: Provides vital calories when oral intake is not possible, contributing to overall nutritional support during illness or recovery.
25% w/v DEXTROSE INJECTION USP Interactions 25% w/v DEXTROSE INJECTION USP
Dextrose solution may interact with several drugs, necessitating careful monitoring and dosage adjustments.
- Insulin and Hypoglycemics: Dextrose raises blood glucose levels, which can reduce the effectiveness of insulin and oral hypoglycemic agents.
- Diuretics: Combined use with diuretics can disturb electrolyte balance, particularly potassium levels.
- Warfarin: High glucose levels might influence warfarin metabolism and anticoagulant control.
- Compatibility: Certain intravenous drugs may be incompatible when mixed with dextrose solutions; always verify before co-administration.
- Corticosteroids and Catecholamines: These agents may increase blood glucose, heightening risk of hyperglycemia when used with dextrose infusion.
Dosage of 25% w/v DEXTROSE INJECTION USP
Dosage is individualized based on patient needs, age, weight, and clinical status.
- Adults: Maintenance or replacement doses typically range between 50 to 250 ml infused over several hours, depending on energy and hydration requirements.
- Emergency Use: In hypoglycemia, 25 to 50 ml may be given as a rapid IV bolus.
- Pediatrics: Weight-based dosing is used; careful titration with close monitoring is essential.
- Adjustments: Modify based on glucose levels, fluid status, renal and cardiac function.
- Parenteral Nutrition: May be combined with other nutrients for total parenteral nutrition in critically ill patients.
Possible side effects of 25% w/v DEXTROSE INJECTION USP
Though generally safe when used correctly, side effects can occur, especially if dosage or administration rate is inappropriate.
- Local Effects: Pain, irritation, or phlebitis at the infusion site due to hypertonicity.
- Hyperglycemia: High blood sugar levels may cause increased thirst, urination, headache, or, in severe cases, diabetic ketoacidosis.
- Electrolyte Imbalance: Shifts in sodium and potassium levels can lead to complications such as edema or cardiac arrhythmias.
- Fluid Overload: Excessive administration may precipitate pulmonary edema or congestive heart failure, particularly in vulnerable patients.
- Allergic Reactions: Rare but may include rash, itching, or anaphylactic reactions.
- Other: Dizziness, nausea, or headache in some individuals.
25% w/v DEXTROSE INJECTION USP Contraindications 25% w/v DEXTROSE INJECTION USP
Use is contraindicated or should be avoided in certain patient populations.
- Uncontrolled Hyperglycemia: Patients with elevated blood sugar or diabetic ketoacidosis should not receive hypertonic dextrose solutions.
- Severe Dehydration Without Electrolyte Correction: Hypertonic solutions may worsen imbalances.
- Hypersensitivity: Known allergy to dextrose or any component.
- Intracranial Hemorrhage: May exacerbate cerebral edema or increase intracranial pressure.
- Severe Renal or Cardiac Dysfunction: Due to risk of fluid overload and electrolyte disturbances.
Storage of 25% w/v DEXTROSE INJECTION USP
To maintain stability and sterility, follow recommended storage conditions:
- Temperature: Store at controlled room temperature (20°C–25°C), avoiding freezing.
- Light Protection: Keep in original packaging to protect from light exposure.
- Handling: Avoid shaking to prevent foaming and contamination.
- Inspection: Do not use if solution is cloudy, discolored, or contains particles.
- Expiry: Adhere to the expiration date on packaging.
- Environment: Store in a clean, dry place away from heat and incompatible substances.
25% w/v DEXTROSE INJECTION USP features an exceptional active ingredient renowned for its potent effects, comprising Dextrose (anhydrous). This powerful formulation provides a superior solution for addressing diverse health concerns. With 250mg/ml concentration and an easily manageable Infusion/Solution for, it remains a preferred option for countless individuals seeking effective treatment.
Introduction
All you need to know about 25% w/v DEXTROSE INJECTION USP .
Welcome to Dwaey, specifically on 25% w/v DEXTROSE INJECTION USP page.
This medicine contains an important and useful components, as it consists of Dextrose (anhydrous).
25% w/v DEXTROSE INJECTION USP is available in the market in concentration 250mg/ml and in the form of Infusion/Solution for.
QATAR PHARMA is the producer of 25% w/v DEXTROSE INJECTION USP and it is imported from QATAR,
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Frequently Asked Questions
25% w/v DEXTROSE INJECTION USP should be stored according to the instructions provided by QATAR PHARMA.
In general, it is recommended to store 25% w/v DEXTROSE INJECTION USP in a cool, dry place, away from direct sunlight
and out of the reach of children.
The duration of treatment with 25% w/v DEXTROSE INJECTION USP may vary depending on the condition being treated
and the guidance of your healthcare provider. It is important to follow the prescribed treatment
plan and continue taking 25% w/v DEXTROSE INJECTION USP for the recommended duration, even if your symptoms improve.
If you have any concerns or questions about the duration of treatment, consult your healthcare provider.
It is important to check with your healthcare provider or read the medication label for specific
instructions regarding alcohol consumption while taking 25% w/v DEXTROSE INJECTION USP. Some medications, including
25% w/v DEXTROSE INJECTION USP, may have interactions with alcohol that can reduce effectiveness, increase side
effects, or pose other risks to your health. It is best to follow the guidance provided by your
healthcare professional.
If you miss a dose of 25% w/v DEXTROSE INJECTION USP, take it as soon as you remember. However, if it is close
to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing
schedule. Do not take a double dose to make up for a missed one unless advised by your healthcare provider.
No, do not stop taking 25% w/v DEXTROSE INJECTION USP without consulting your healthcare provider, even if your
symptoms improve. It is important to complete the full course of treatment as prescribed. Stopping
the medication prematurely may lead to a relapse or incomplete resolution of the condition. If you
have concerns about the duration of treatment, consult your healthcare provider for guidance.
It is important to consult your healthcare provider before taking 25% w/v DEXTROSE INJECTION USP if you are
pregnant or breastfeeding. They will be able to assess the potential risks and benefits based on your
specific situation. Please note that the safety and suitability of 25% w/v DEXTROSE INJECTION USP during pregnancy
or breastfeeding may depend on the active substance [Active Substance], concentration 250mg/ml,
and the specific recommendations of QATAR PHARMA.
The effects of 25% w/v DEXTROSE INJECTION USP on your ability to drive or operate machinery can vary depending on
the active substance [Active Substance], concentration 250mg/ml, and individual factors.
Some medications may cause drowsiness, dizziness, or other side effects that can impair your judgment
or coordination. It is important to read the medication label or consult your healthcare provider to
understand any potential effects on your ability to perform tasks that require alertness.
The instructions for taking 25% w/v DEXTROSE INJECTION USP with or without food may vary depending on the medication
and the recommendations of QATAR PHARMA. Some medications may be more effective when taken with
food to enhance absorption or reduce stomach irritation, while others may need to be taken on an empty
stomach for optimal absorption. Read the medication label or consult your healthcare provider for specific instructions.
The use of 25% w/v DEXTROSE INJECTION USP in children or elderly individuals may depend on various factors, including
the specific medication, type Infusion/Solution for, and the recommendations of QATAR PHARMA. Some
medications may have specific dosing instructions or precautions for these age groups. Consult your
healthcare provider or read the medication label for information regarding the safe and appropriate use
of 25% w/v DEXTROSE INJECTION USP in children or elderly individuals.
Dwaey
All medical information published on the Dwaey website aims to increase medical awareness and health education among users. However, it is not a substitute for professional medical advice. Always consult with a specialist doctor. We strongly advise against using any information or medicine found on the site without referring to your healthcare provider.
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