What is 25% w/v DEXTROSE INJECTION USP
25% w/v Dextrose Injection USP is a sterile, nonpyrogenic, hypertonic solution containing 250 mg/mL of dextrose (anhydrous) in water for injection. Packaged in 50 mL plastic bags, this intravenous solution is primarily used for:
- Acute management of hypoglycemia in patients unable to take oral glucose.
- Short-term fluid and caloric supplementation when oral intake is inadequate or contraindicated.
- Adjunct therapy in treating hyperkalemia by promoting intracellular potassium shift.
Each milliliter provides approximately 0.85 kcal, serving as a rapid source of energy. Due to its hypertonicity, administration should be carefully monitored to avoid complications such as phlebitis or thrombosis.
How to use 25% w/v DEXTROSE INJECTION USP
Administration of 25% Dextrose Injection should be conducted under strict medical supervision, adhering to the following guidelines:
- Route: Intravenous (IV) injection only. Preferably through a central vein to minimize the risk of venous irritation.
- Preparation:
- Inspect the solution for clarity and absence of particulate matter.
- Ensure the container is intact and the solution is clear before use.
- Administration:
- Administer slowly to prevent hyperglycemia and hyperosmolar syndrome.
- Monitor blood glucose levels before, during, and after administration.
- Precautions:
- Do not administer subcutaneously or intramuscularly.
- Avoid simultaneous infusion with blood products through the same line to prevent pseudoagglutination.
Always follow institutional protocols and consult prescribing information for specific administration instructions.
Mode of Action 25% w/v DEXTROSE INJECTION USP
Dextrose (glucose) is a monosaccharide that serves as a primary energy source for the body's cells. When administered intravenously:
- Rapidly increases blood glucose levels, providing immediate energy, especially vital in hypoglycemic states.
- Facilitates cellular uptake of glucose via insulin-mediated pathways, supporting metabolic functions.
- Promotes osmotic diuresis in high concentrations, aiding in the management of hyperkalemia by shifting potassium intracellularly.
The hypertonic nature of the solution draws water into the vascular compartment, which can be beneficial in certain clinical scenarios but requires careful monitoring to prevent fluid overload.
25% w/v DEXTROSE INJECTION USP Interactions 25% w/v DEXTROSE INJECTION USP
While dextrose solutions are generally compatible with many medications, certain interactions and considerations include:
- Insulin: Co-administration enhances cellular glucose uptake; monitor for hypoglycemia.
- Potassium chloride: When used together, dextrose can help mitigate hyperkalemia; monitor serum potassium levels.
- Blood products: Avoid mixing in the same infusion line to prevent pseudoagglutination.
- Medications affecting glucose metabolism: Corticosteroids, thiazide diuretics, and others may alter glucose tolerance; monitor blood glucose accordingly.
Always consult compatibility charts and institutional guidelines before co-administering medications with dextrose solutions.
Dosage of 25% w/v DEXTROSE INJECTION USP
Dosage should be individualized based on patient needs, clinical condition, and response to therapy. General guidelines include:
- Adults:
- For hypoglycemia: 10–25 g of dextrose (40–100 mL of 25% solution) administered slowly IV.
- Pediatrics:
- For hypoglycemia: 0.5–1 g/kg (2–4 mL/kg of 25% solution) administered slowly IV.
Monitor blood glucose levels closely during and after administration. Adjust dosage as necessary based on clinical response and laboratory values.
Possible side effects of 25% w/v DEXTROSE INJECTION USP
Potential adverse effects include:
- Local reactions: Pain, redness, or swelling at the injection site.
- Metabolic disturbances: Hyperglycemia, hypokalemia, or fluid overload.
- Vascular complications: Phlebitis or thrombosis, especially with peripheral administration.
- Allergic reactions: Rare, but may include rash or hypersensitivity responses.
Promptly report any adverse reactions to the healthcare provider. Monitoring and supportive care may be necessary to manage side effects.
25% w/v DEXTROSE INJECTION USP Contraindications 25% w/v DEXTROSE INJECTION USP
Contraindications include:
- Known hypersensitivity to dextrose or any component of the formulation.
- Hyperglycemia or diabetic coma with elevated blood glucose levels.
- Intracranial or intraspinal hemorrhage: Hypertonic solutions may exacerbate these conditions.
- Severe dehydration: May worsen hyperosmolar states.
- Delirium tremens: In dehydrated patients, administration may be contraindicated.
Assess patient history and current clinical status before initiating therapy.
Storage of 25% w/v DEXTROSE INJECTION USP
Proper storage is essential to maintain the integrity and efficacy of the solution:
- Temperature: Store at 20–25°C (68–77°F); avoid excessive heat.
- Protection: Keep away from light and moisture; do not freeze.
- Inspection: Before use, check for clarity and absence of particulate matter; do not use if the solution is discolored or contains particles.
- Single-use: Discard any unused portion; do not save for later use.
Adhering to storage guidelines ensures patient safety and therapeutic effectiveness.
25% w/v DEXTROSE INJECTION USP features an exceptional active ingredient renowned for its potent effects, comprising Dextrose (anhydrous). This powerful formulation provides a superior solution for addressing diverse health concerns. With 250mg/ml concentration and an easily manageable Infusion/Solution for, it remains a preferred option for countless individuals seeking effective treatment.
Introduction
All you need to know about 25% w/v DEXTROSE INJECTION USP .
Welcome to Dwaey, specifically on 25% w/v DEXTROSE INJECTION USP page.
This medicine contains an important and useful components, as it consists of Dextrose (anhydrous).
25% w/v DEXTROSE INJECTION USP is available in the market in concentration 250mg/ml and in the form of Infusion/Solution for.
QATAR PHARMA is the producer of 25% w/v DEXTROSE INJECTION USP and it is imported from QATAR,
The most popular alternatives of 25% w/v DEXTROSE INJECTION USP are listed downward .
-
Active Substance
-
Size
-
Indications
-
Type
-
Company
Frequently Asked Questions
25% w/v DEXTROSE INJECTION USP should be stored according to the instructions provided by QATAR PHARMA.
In general, it is recommended to store 25% w/v DEXTROSE INJECTION USP in a cool, dry place, away from direct sunlight
and out of the reach of children.
The duration of treatment with 25% w/v DEXTROSE INJECTION USP may vary depending on the condition being treated
and the guidance of your healthcare provider. It is important to follow the prescribed treatment
plan and continue taking 25% w/v DEXTROSE INJECTION USP for the recommended duration, even if your symptoms improve.
If you have any concerns or questions about the duration of treatment, consult your healthcare provider.
It is important to check with your healthcare provider or read the medication label for specific
instructions regarding alcohol consumption while taking 25% w/v DEXTROSE INJECTION USP . Some medications, including
25% w/v DEXTROSE INJECTION USP , may have interactions with alcohol that can reduce effectiveness, increase side
effects, or pose other risks to your health. It is best to follow the guidance provided by your
healthcare professional.
If you miss a dose of 25% w/v DEXTROSE INJECTION USP , take it as soon as you remember. However, if it is close
to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing
schedule. Do not take a double dose to make up for a missed one unless advised by your healthcare provider.
No, do not stop taking 25% w/v DEXTROSE INJECTION USP without consulting your healthcare provider, even if your
symptoms improve. It is important to complete the full course of treatment as prescribed. Stopping
the medication prematurely may lead to a relapse or incomplete resolution of the condition. If you
have concerns about the duration of treatment, consult your healthcare provider for guidance.
It is important to consult your healthcare provider before taking 25% w/v DEXTROSE INJECTION USP if you are
pregnant or breastfeeding. They will be able to assess the potential risks and benefits based on your
specific situation. Please note that the safety and suitability of 25% w/v DEXTROSE INJECTION USP during pregnancy
or breastfeeding may depend on the active substance [Active Substance], concentration 250mg/ml,
and the specific recommendations of QATAR PHARMA.
The effects of 25% w/v DEXTROSE INJECTION USP on your ability to drive or operate machinery can vary depending on
the active substance [Active Substance], concentration 250mg/ml, and individual factors.
Some medications may cause drowsiness, dizziness, or other side effects that can impair your judgment
or coordination. It is important to read the medication label or consult your healthcare provider to
understand any potential effects on your ability to perform tasks that require alertness.
The instructions for taking 25% w/v DEXTROSE INJECTION USP with or without food may vary depending on the medication
and the recommendations of QATAR PHARMA. Some medications may be more effective when taken with
food to enhance absorption or reduce stomach irritation, while others may need to be taken on an empty
stomach for optimal absorption. Read the medication label or consult your healthcare provider for specific instructions.
The use of 25% w/v DEXTROSE INJECTION USP in children or elderly individuals may depend on various factors, including
the specific medication, type Infusion/Solution for, and the recommendations of QATAR PHARMA. Some
medications may have specific dosing instructions or precautions for these age groups. Consult your
healthcare provider or read the medication label for information regarding the safe and appropriate use
of 25% w/v DEXTROSE INJECTION USP in children or elderly individuals.
Dwaey
All medical information published on the Dwaey website aims to increase medical awareness and health education among users. However, it is not a substitute for professional medical advice. Always consult with a specialist doctor. We strongly advise against using any information or medicine found on the site without referring to your healthcare provider.
Related Products
0 Comments