DIGEX Tablets

What is DIGEX

DIGEX is a chewable antacid tablet formulated with a co-dried combination of Aluminium hydroxide and Magnesium carbonate. It is commonly used to provide rapid relief from symptoms associated with excess stomach acid, such as heartburn, acid indigestion, and upset stomach. The co-dried formulation offers enhanced efficacy and better palatability.

• Aluminium hydroxide: A slow-acting antacid that neutralizes stomach acid and provides longer-lasting relief.
• Magnesium carbonate: A fast-acting antacid that rapidly counteracts stomach acid and also aids in relieving constipation.
• The dual-action combination balances the constipating effect of aluminium with the laxative properties of magnesium.
• DIGEX is available in a convenient tablet form, making it easy to administer and suitable for both home and on-the-go use.

It is ideal for patients suffering from non-ulcer dyspepsia, gastroesophageal reflux disease (GERD), peptic ulcers, or as adjunctive therapy in hyperacidity-related conditions.

How to use DIGEX

Proper administration of DIGEX is key to ensuring maximum effectiveness and safety. Follow the directions on the product label or as directed by a healthcare professional.

• Dosage form: Chewable tablets.
• Method: Chew each tablet thoroughly before swallowing. Do not swallow whole.
• Timing: Typically taken 1 to 3 hours after meals and at bedtime, or as needed for symptom relief.
• With or without food: Can be taken with or without food. However, taking it after meals may provide more prolonged relief.
• Water: May be taken with a small amount of water if desired, though not necessary.

Important tips:

• Do not exceed the recommended daily dose unless advised by a healthcare provider.
• For persistent symptoms, consult a doctor instead of prolonged self-medication.
• Not recommended for children under 12 years without medical advice.

Mode of Action DIGEX

DIGEX works through a simple but effective neutralization process that reduces gastric acidity and alleviates discomfort caused by acid-related conditions.

• Aluminium hydroxide: Reacts with hydrochloric acid in the stomach to form aluminium chloride and water, neutralizing acid slowly and providing sustained relief.
• Magnesium carbonate: Rapidly reacts with stomach acid to produce magnesium chloride, carbon dioxide, and water, offering quick symptom alleviation.
• The combination ensures both immediate and prolonged acid neutralization.
• By buffering the acid, DIGEX helps protect the stomach lining and esophageal mucosa from erosion and inflammation.
• Additionally, the presence of magnesium helps counterbalance the constipating effect often associated with aluminium-based antacids.

This dual-action mechanism is particularly useful in the symptomatic treatment of GERD, gastritis, and peptic ulcer disease.

DIGEX Interactions DIGEX

DIGEX, like all antacids, may interact with several medications due to its effects on gastric pH and absorption dynamics.

• Antibiotics (e.g., tetracyclines, ciprofloxacin): May bind with antacids, reducing their absorption and effectiveness. Separate doses by at least 2 hours.
• Iron supplements: Reduced absorption when taken concurrently. Administer DIGEX 2 hours before or after iron products.
• Levothyroxine: DIGEX may reduce the effectiveness of thyroid hormone replacement therapy. Take at least 4 hours apart.
• Azole antifungals (e.g., ketoconazole): Increased gastric pH may impair drug absorption. Monitor closely or consider alternatives.
• Bisphosphonates (e.g., alendronate): Reduced absorption; space antacids and bisphosphonates by several hours.

Always inform your healthcare provider about all medications you are taking to avoid clinically significant interactions.

Dosage of DIGEX

The recommended dosage for DIGEX should always be adhered to as instructed on the label or as advised by a healthcare professional.

• Adults and adolescents (12 years and older): 1–2 tablets to be chewed as needed, preferably after meals and at bedtime.
• Maximum daily dose: Do not exceed 8 tablets in a 24-hour period unless directed by a physician.
• Children under 12: Use only under medical supervision.

Key considerations:

• Do not use the product continuously for more than 2 weeks without medical consultation.
• For best results, chew thoroughly before swallowing.
• Monitor for signs of overuse, especially in patients with renal impairment or those on low-phosphate diets.

Possible side effects of DIGEX

DIGEX is generally well tolerated, but some individuals may experience side effects, particularly with prolonged use or in high doses.

• Common side effects:
  • Constipation (due to aluminium hydroxide)
  • Diarrhea (from magnesium carbonate)
  • Abdominal cramping or bloating
• Less common effects:
  • Altered taste sensation
  • Nausea
  • Stomach discomfort if not chewed properly
• Rare but serious:
  • Hypophosphatemia (long-term use of aluminium antacids)
  • Hypermagnesemia (in individuals with kidney dysfunction)
  • Allergic reactions like rash, itching, or swelling (rare)

If you experience unusual symptoms or signs of allergic reaction, seek medical help promptly.

DIGEX Contraindications DIGEX

DIGEX should be avoided in specific populations or clinical conditions where its use may pose health risks.

• Known hypersensitivity: Allergy to aluminium hydroxide, magnesium carbonate, or any other component of the tablet.
• Severe renal impairment: Risk of aluminium and magnesium accumulation leading to toxicity.
• Low phosphate levels (hypophosphatemia): Aluminium compounds can bind phosphate, worsening the condition.
• Severe dehydration or electrolyte imbalance: May exacerbate magnesium-related side effects.
• Children under 6 years: Use only under medical supervision due to potential electrolyte disturbances.

Always consult your doctor before using DIGEX if you have a chronic condition, are pregnant, or are breastfeeding.

Storage of DIGEX

Proper storage ensures the integrity, safety, and effectiveness of DIGEX tablets over their shelf life.

• Store at room temperature: Typically between 20°C to 25°C (68°F to 77°F).
• Protect from moisture and heat: Keep the container tightly closed and avoid exposure to direct sunlight.
• Do not refrigerate or freeze: Temperature extremes may affect tablet integrity and dissolution.
• Keep out of reach of children: Ensure the packaging is securely closed and stored safely.
• Check expiration date: Do not use past the expiry date printed on the package or bottle.

Dispose of unused or expired medication responsibly in accordance with local pharmacy or environmental guidelines.