DI-GEL (Lemon/Orange) Tablets

What is DI-GEL (Lemon/Orange)

DI-GEL (Lemon/Orange) Tablets are over-the-counter chewable antacid and anti-gas tablets formulated to relieve gastrointestinal discomfort such as:

• Heartburn
• Acid indigestion
• Upset stomach
• Bloating and pressure due to gas

Each tablet contains a combination of:

• Aluminum Hydroxide – a slow-acting antacid that neutralizes stomach acid and provides prolonged relief.
• Magnesium Hydroxide – a fast-acting antacid that balances the constipating effect of aluminum.
• Simethicone – an anti-foaming agent that helps break up and expel intestinal gas.

The pleasant lemon or orange flavor makes DI-GEL tablets easy and convenient to take on-the-go, without the need for water. These tablets are commonly used by individuals suffering from dietary or stress-induced digestive issues. DI-GEL is suitable for adults and children over 12 years and is generally well-tolerated when used as directed.

How to use DI-GEL (Lemon/Orange)

Proper administration of DI-GEL chewable tablets ensures optimal relief from digestive discomfort. Always follow the instructions on the package or your healthcare provider’s recommendations.

• Chew Thoroughly: Chew 1 to 2 tablets completely before swallowing. Do not swallow the tablet whole.
• No Water Required: Can be taken without water, making it suitable for use while traveling or at work.
• Timing of Use:
  • Take after meals and at bedtime, or as symptoms occur.
  • May also be taken between meals if needed.
• Maximum Dose:
  • Do not exceed 8 tablets in 24 hours unless advised by a physician.
  • Use for no more than 2 weeks unless directed by a healthcare provider.

Consult your doctor if your symptoms persist or worsen, or if you're using other medications. DI-GEL is not intended for long-term use without medical supervision.

Mode of Action DI-GEL (Lemon/Orange)

DI-GEL chewable tablets work through the combined pharmacological actions of its three active ingredients. Each serves a specific role in relieving symptoms associated with excess stomach acid and gas.

• Aluminum Hydroxide:
  • Neutralizes gastric acid by forming aluminum chloride upon contact with hydrochloric acid in the stomach.
  • Soothes irritated gastric mucosa by reducing acidity.
  • Provides longer-lasting acid suppression compared to magnesium salts.
• Magnesium Hydroxide:
  • Rapidly reacts with stomach acid to form magnesium chloride and water.
  • Acts quickly to relieve acute symptoms like burning sensation in the chest or throat.
  • Has a mild osmotic laxative effect, which helps prevent constipation caused by aluminum salts.
• Simethicone:
  • Acts as a surfactant to reduce surface tension of gas bubbles.
  • Allows gas bubbles to coalesce and be expelled more easily through belching or flatulence.
  • Does not affect stomach acid or digestion directly, making it safe for use alongside antacids.

The combination ensures rapid and sustained relief from indigestion and gas, addressing both acidity and bloating in a single dose.

DI-GEL (Lemon/Orange) Interactions DI-GEL (Lemon/Orange)

Though generally safe, DI-GEL can interact with certain medications by altering their absorption, efficacy, or metabolism. These interactions are primarily due to changes in stomach pH or physical binding with other drugs.

• Antibiotics: May reduce the absorption of tetracyclines (e.g., doxycycline) and fluoroquinolones (e.g., ciprofloxacin). Take DI-GEL 2–4 hours before or after these medications.
• Thyroid Hormones: DI-GEL may impair absorption of levothyroxine. Take levothyroxine at least 4 hours apart.
• Iron Supplements: Reduced iron absorption can occur; separate administration by several hours is advised.
• Digoxin: Antacids may reduce the bioavailability of digoxin; monitor heart rate and drug levels.
• Bisphosphonates: Such as alendronate — absorption may be significantly reduced if taken with antacids.
• Other Antacids or Laxatives: Concurrent use can increase the risk of electrolyte disturbances or gastrointestinal effects.

Always consult a healthcare provider before using DI-GEL if you are on any chronic medications or have a complex medication schedule. Spacing medications appropriately helps prevent unwanted interactions.

Dosage of DI-GEL (Lemon/Orange)

Adhering to the correct dosage of DI-GEL ensures optimal efficacy and safety. The following is the standard dosing recommendation unless otherwise directed by a physician:

• Adults and Children ≥12 Years:
  • Chew 1 to 2 tablets as needed after meals and at bedtime.
  • Maximum: Do not exceed 8 tablets in 24 hours.
• Children Under 12 Years:
  • Use only under the advice and supervision of a healthcare provider.
• Instructions:
  • Chew tablets thoroughly before swallowing.
  • No need to take with water.
  • Do not use continuously for more than 14 days unless advised.

For chronic symptoms or frequent dosing, consult your doctor to evaluate for underlying conditions such as GERD or peptic ulcer disease. Long-term self-treatment may delay diagnosis.

Possible side effects of DI-GEL (Lemon/Orange)

Most users tolerate DI-GEL well. However, some individuals may experience side effects, particularly if the product is used frequently or in large doses.

• Common Side Effects:
  • Constipation (due to aluminum)
  • Diarrhea (due to magnesium)
  • Mild stomach cramps or nausea
• Less Common Side Effects:
  • Dry mouth
  • Metallic taste
  • Belching or bloating
• Serious Side Effects (Rare):
  • Hypermagnesemia: Symptoms include slow reflexes, confusion, and irregular heartbeat (especially in kidney patients)
  • Aluminum toxicity: Risk increases in patients with renal impairment
  • Allergic reactions: Rash, itching, swelling (rare but possible)

If you experience any unusual or persistent symptoms, discontinue use and seek medical advice. People with renal disease should consult a doctor before using aluminum or magnesium-based antacids.

DI-GEL (Lemon/Orange) Contraindications DI-GEL (Lemon/Orange)

Certain individuals should avoid using DI-GEL tablets due to potential health risks or reduced efficacy. Contraindications include:

• Severe Renal Impairment: Risk of aluminum and magnesium accumulation, which may cause toxicity.
• Hypophosphatemia: Aluminum hydroxide binds dietary phosphate, worsening low phosphate levels.
• Appendicitis or Suspected GI Obstruction: Use may mask symptoms and delay necessary intervention.
• Allergy: Known hypersensitivity to aluminum hydroxide, magnesium hydroxide, simethicone, or tablet excipients/flavorings.
• Long-term Use Without Diagnosis: Persistent symptoms may indicate underlying conditions like ulcers or GERD, requiring physician evaluation.

Always review your health history and consult your doctor before initiating DI-GEL, particularly if you're pregnant, breastfeeding, elderly, or managing chronic disease.

Storage of DI-GEL (Lemon/Orange)

Proper storage ensures the tablets maintain their integrity, flavor, and effectiveness. Here are the best practices for storing DI-GEL tablets:

• Temperature: Store at 15°C–30°C (59°F–86°F). Avoid excessive heat or humidity.
• Original Packaging: Keep in the original container with the lid tightly closed.
• Avoid Moisture: Do not store in bathrooms or near sinks. Moisture can degrade tablet quality.
• Keep Out of Reach of Children: Store in a secure location to avoid accidental ingestion.
• Check Expiry Date: Do not use expired products. Discard any tablets that are discolored, crumbling, or have an unusual odor.

Following these guidelines will help preserve the safety, flavor, and effectiveness of DI-GEL tablets throughout their shelf life.