DI-GEL (Lemon/Orange) Liquid (Oral)

What is DI-GEL (Lemon/Orange)

DI-GEL is an over-the-counter oral liquid medication used to relieve symptoms associated with excess stomach acid and gas. It contains a combination of three active ingredients: Aluminum Hydroxide, Magnesium Hydroxide (both antacids), and Simethicone (an anti-foaming agent).

• Form: Oral liquid suspension, available in lemon and orange flavors for palatability.
• Size: Supplied in 6 oz bottles, suitable for multiple doses.
• Primary Indications:
  • Heartburn
  • Acid indigestion
  • Upset stomach
  • Bloating or gas discomfort
• Combination Action: The formula neutralizes stomach acid and reduces gas bubbles in the gastrointestinal tract, providing fast relief.
• Safe for Occasional Use: DI-GEL is commonly used as needed, but prolonged or excessive use should be monitored by a healthcare provider.

This medication is often recommended for those who experience digestive discomfort due to dietary choices, stress, or occasional gastric disturbances.

How to use DI-GEL (Lemon/Orange)

Proper use of DI-GEL ensures fast and effective relief from digestive discomfort. Always follow the label instructions or your doctor’s recommendations for best results.

• Shake Well: As a suspension, DI-GEL must be shaken thoroughly before each use to ensure uniform distribution of active ingredients.
• Dosage Timing:
  • Take after meals and at bedtime, or as directed by your healthcare provider.
  • It may also be used on an as-needed basis when symptoms occur.
• Measuring: Use a proper dosing cup or spoon — not household utensils — to ensure accurate dosage.
• With or Without Food: Can be taken regardless of meals, but post-meal administration enhances acid-neutralizing effects.
• Hydration: Drink a small amount of water after taking the dose to help the medicine coat the stomach lining.

Do not exceed the recommended daily dosage unless instructed by a healthcare provider. Prolonged use without medical advice may lead to unwanted side effects or mask underlying issues.

Mode of Action DI-GEL (Lemon/Orange)

The relief provided by DI-GEL stems from the combined actions of its three main ingredients, each targeting a specific type of gastrointestinal discomfort.

• Aluminum Hydroxide:
  • Neutralizes hydrochloric acid (HCl) in the stomach, reducing acidity and relieving heartburn and indigestion.
  • Forms aluminum chloride in the stomach, helping to buffer the acid environment.
• Magnesium Hydroxide:
  • Acts as a fast-acting antacid, neutralizing stomach acid quickly.
  • Helps balance the constipating effect of aluminum hydroxide by promoting mild bowel movement.
• Simethicone:
  • Breaks up gas bubbles in the stomach and intestines, making it easier to eliminate gas and relieve bloating and pressure.
  • Acts as a surfactant, decreasing the surface tension of gas bubbles.

This triple-action formula addresses both the acid component (heartburn, indigestion) and gas-related discomfort (bloating, flatulence), making DI-GEL an efficient option for multiple symptoms.

DI-GEL (Lemon/Orange) Interactions DI-GEL (Lemon/Orange)

Though DI-GEL is available over-the-counter, it may interact with several prescription and non-prescription medications. These interactions can reduce the effectiveness of your medicines or enhance side effects.

• Antibiotics: May reduce absorption of tetracyclines, fluoroquinolones (like ciprofloxacin), and others due to chelation with aluminum and magnesium ions.
• Thyroid Medications: May interfere with levothyroxine absorption. Administer DI-GEL at least 4 hours before or after these drugs.
• Iron Supplements: Can bind with antacids, reducing iron absorption. Separate doses by 2 hours or more.
• Heart Medications: Some cardiac drugs like digoxin or beta blockers may have reduced bioavailability when taken with antacids.
• Diuretics and Bisphosphonates: Potential for altered electrolyte levels or reduced effectiveness if taken concurrently.

Always inform your healthcare provider or pharmacist about all medications, vitamins, and supplements you're taking before using DI-GEL, especially if used frequently.

Dosage of DI-GEL (Lemon/Orange)

Accurate dosing is key to achieving symptomatic relief while minimizing the risk of side effects. Dosage recommendations can vary based on age, symptom severity, and frequency of use.

• Adults and Teenagers (12+ years):
  • Take 2 to 4 teaspoonfuls (10 to 20 mL) as needed, after meals and at bedtime.
  • Do not exceed 12 teaspoonfuls (60 mL) in 24 hours unless directed by a physician.
• Children Under 12: Use only under medical supervision. Dosage is not routinely recommended without a doctor’s guidance.
• Frequency: Can be taken up to 4 times daily, typically after meals and before sleep.
• Chronic Use: Should not be used continuously for more than 2 weeks unless advised by a healthcare professional.

If symptoms persist or worsen despite appropriate dosing, seek medical evaluation to rule out more serious gastrointestinal conditions.

Possible side effects of DI-GEL (Lemon/Orange)

While DI-GEL is generally well tolerated, it may cause side effects, particularly when used in high doses or for extended periods.

• Common Side Effects:
  • Mild diarrhea (due to magnesium hydroxide)
  • Constipation (due to aluminum hydroxide)
  • Nausea or stomach cramps
• Less Common Effects:
  • Dry mouth or unpleasant chalky taste
  • Loss of appetite
• Serious Side Effects (Rare):
  • Electrolyte imbalance (particularly in kidney-impaired patients)
  • Muscle weakness, fatigue, or mood changes indicating elevated magnesium or aluminum levels
  • Allergic reactions such as rash, itching, or swelling

Seek immediate medical attention if signs of a severe allergic reaction appear, or if you notice changes in bowel habits, confusion, or irregular heartbeat.

DI-GEL (Lemon/Orange) Contraindications DI-GEL (Lemon/Orange)

DI-GEL is not suitable for all individuals. Certain medical conditions or circumstances may warrant its avoidance or careful monitoring under a healthcare provider’s supervision.

• Renal Impairment: Patients with kidney disease may have difficulty eliminating aluminum and magnesium, increasing the risk of toxicity or electrolyte imbalance.
• Hypophosphatemia: Chronic use of aluminum-containing antacids can deplete phosphate levels, exacerbating this condition.
• Severe Appendicitis or Bowel Obstruction: Symptoms such as abdominal pain, vomiting, or distention may mask or delay diagnosis of serious conditions.
• Allergy to Ingredients: Known hypersensitivity to simethicone, aluminum, or magnesium compounds.
• Pregnancy and Lactation: Generally considered safe when used occasionally and appropriately, but consult a physician for routine use.

Always disclose your full medical history to your doctor before using DI-GEL, especially if you are on multiple medications or have chronic health issues.

Storage of DI-GEL (Lemon/Orange)

Proper storage ensures that DI-GEL maintains its potency and safety throughout its shelf life. Since it is a suspension, environmental conditions can impact its stability.

• Temperature: Store at room temperature between 15°C to 30°C (59°F to 86°F). Do not freeze.
• Keep Away from Heat: Avoid direct sunlight or storing near heat sources as this may degrade the formulation.
• Cap Tightly Closed: Always close the bottle cap securely after each use to avoid contamination and evaporation.
• Shake Before Use: Suspension should be shaken well before each dose for proper consistency.
• Child Safety: Keep out of reach of children to prevent accidental ingestion.
• Expiry: Do not use past the expiration date printed on the bottle. Discard unused product responsibly.

Proper storage not only preserves the effectiveness of the product but also reduces the risk of accidental misuse or microbial growth.