D-FORTE 50,000 IU Capsules (Soft Gelatin)

What is D-FORTE 50,000 IU

What is D-FORTE 50,000 IU?

D-FORTE 50,000 IU is a high-strength vitamin D supplement in the form of soft gelatin capsules, containing Ergocalciferol (Vitamin D2) as its active ingredient. It is primarily used to treat and prevent vitamin D deficiencies and related bone disorders.

• Formulation: Each capsule contains 50,000 IU of Vitamin D (as Ergocalciferol).
• Packaging: Available in a pack of 12 soft gelatin capsules.
• Purpose: Supports calcium and phosphate balance for healthy bones and teeth.
• Therapeutic Uses: Treats rickets, osteomalacia, hypoparathyroidism, and helps manage deficiency in malabsorption syndromes.
• Target Patients: Typically prescribed to individuals with low sun exposure, chronic illness, or dietary deficiency in vitamin D.

D-FORTE helps replenish depleted vitamin D levels, which is essential for calcium absorption and immune function. It is especially useful in patients who require intermittent high-dose supplementation.

How to use D-FORTE 50,000 IU

D-FORTE should be used under medical supervision, particularly at such high doses. Proper administration ensures maximum benefit while minimizing the risk of side effects like hypercalcemia.

• Route: Oral – swallow the soft gelatin capsule whole with water.
• Frequency: Usually taken once weekly or as directed by a healthcare professional.
• With or Without Food: Preferably taken with meals to enhance absorption.
• Do Not: Crush, chew, or break the capsule.
• Missed Dose: Take it as soon as remembered unless it's close to the next dose. Do not double dose.
• Important: Regular monitoring of blood calcium and vitamin D levels is recommended during prolonged use.

Patients should not self-medicate with D-FORTE due to its potency. It should be taken strictly as prescribed, especially in individuals with kidney or liver issues, or those on other supplements or medications.

Mode of Action D-FORTE 50,000 IU

The active compound in D-FORTE, Ergocalciferol (Vitamin D2), undergoes metabolic activation in the liver and kidneys to exert its physiological effects.

• Liver Conversion: Ergocalciferol is first hydroxylated in the liver to form 25-hydroxyvitamin D2.
• Kidney Activation: It is further converted in the kidneys to the biologically active form 1,25-dihydroxyvitamin D2 (calcitriol).
• Biological Effects: Calcitriol promotes intestinal absorption of calcium and phosphate, supporting bone mineralization.
• Hormonal Role: It modulates parathyroid hormone secretion to help regulate serum calcium levels.
• Immunomodulatory Action: Also influences immune response and has roles in cell growth and differentiation.

This dual organ activation process ensures that the body maintains optimal calcium-phosphate homeostasis, which is critical for skeletal strength and overall health.

D-FORTE 50,000 IU Interactions D-FORTE 50,000 IU

Like other high-dose vitamin D preparations, D-FORTE may interact with various drugs, which can affect its efficacy or cause adverse effects.

• Diuretics (Thiazides): Increased risk of hypercalcemia when used together.
• Digitalis Glycosides (e.g., Digoxin): Risk of arrhythmia due to elevated calcium levels.
• Anticonvulsants (Phenytoin, Phenobarbital): May increase vitamin D metabolism, reducing its efficacy.
• Cholestyramine and Orlistat: Reduce absorption of fat-soluble vitamins like Ergocalciferol.
• Magnesium-containing products: Caution advised in renal failure; co-administration may cause hypermagnesemia.

Always inform your doctor about all current medications and supplements before starting D-FORTE to avoid potential interactions.

Dosage of D-FORTE 50,000 IU

The dosage of D-FORTE depends on the condition being treated, age, nutritional status, and baseline serum vitamin D levels.

• Deficiency Treatment: 50,000 IU once weekly for 6–8 weeks.
• Maintenance Dose: 1 capsule every 2–4 weeks or as advised.
• Osteomalacia/Rickets: Weekly dosing under supervision until serum vitamin D levels normalize.
• Malabsorption Syndromes: Higher frequency may be required; monitoring is essential.
• Elderly: May require regular supplementation due to reduced skin synthesis and absorption.

All dosing should be personalized and based on clinical evaluation and laboratory tests, especially in high-risk or renal-compromised patients.

Possible side effects of D-FORTE 50,000 IU

While D-FORTE is generally well tolerated, excessive intake or prolonged use may lead to adverse reactions, mostly related to hypervitaminosis D.

• Common Side Effects: Nausea, vomiting, constipation, loss of appetite.
• Metabolic Effects: Hypercalcemia symptoms include muscle weakness, confusion, polyuria, and dehydration.
• Renal Issues: Nephrocalcinosis or kidney stones with chronic excessive use.
• Others: Metallic taste, dry mouth, fatigue, and arrhythmias in sensitive individuals.

Monitoring serum calcium and vitamin D levels can help prevent serious side effects. Discontinue use and consult a physician if toxicity symptoms occur.

D-FORTE 50,000 IU Contraindications D-FORTE 50,000 IU

D-FORTE is contraindicated in certain populations due to the risk of serious complications associated with vitamin D excess.

• Hypercalcemia: Use is contraindicated in patients with elevated blood calcium levels.
• Hypervitaminosis D: Should not be used in individuals already receiving high-dose vitamin D therapy.
• Severe Renal Impairment: Risk of hyperphosphatemia and calcium deposits in soft tissues.
• Hypersensitivity: Allergy to ergocalciferol or any capsule component.

Careful patient evaluation should precede the initiation of D-FORTE, especially in individuals with a history of calcium metabolism disorders or kidney issues.

Storage of D-FORTE 50,000 IU

Proper storage ensures D-FORTE remains effective and safe for use over its intended shelf life.

• Temperature: Store below 25°C (77°F) in a dry place.
• Light Sensitivity: Protect from direct sunlight and UV exposure.
• Moisture: Keep in original packaging to prevent moisture damage.
• Keep Out of Reach: Store away from children and pets.
• Do Not Freeze: Freezing may alter capsule integrity.

Check the expiration date on the package and do not use the product beyond that. Improper storage may lead to reduced potency or contamination.