DEZCORT 6mg Tablet

What is DEZCORT 6mg

DEZCORT 6mg is a pharmaceutical tablet containing the active ingredient Deflazacort, a synthetic glucocorticoid (corticosteroid). Deflazacort is mainly used for its potent anti-inflammatory and immunosuppressive properties. It is often prescribed to manage a variety of chronic conditions where controlling inflammation or immune response is critical. DEZCORT is known for having a slightly better side effect profile compared to older corticosteroids like prednisolone, particularly regarding bone and metabolic health.

• Generic Name: Deflazacort
• Strength: 6 mg per tablet
• Common Indications:
  • Autoimmune diseases (e.g., rheumatoid arthritis, lupus)
  • Chronic inflammatory diseases (e.g., asthma, inflammatory bowel disease)
  • Neuromuscular disorders (e.g., Duchenne Muscular Dystrophy)
  • Severe allergic reactions

By modulating immune responses and inflammation, DEZCORT 6mg provides critical symptomatic relief and prevents disease progression in many conditions.

How to use DEZCORT 6mg

Using DEZCORT 6mg correctly is essential to ensure maximum benefits while minimizing potential side effects.

• Route of Administration: Oral, with a glass of water.
• With or Without Food: Preferably taken with food to avoid gastrointestinal irritation.
• Timing: Generally recommended once daily, ideally in the morning to align with the body's natural cortisol rhythm.
• Important Usage Instructions:
  • Strictly follow the dosing schedule prescribed by your healthcare provider.
  • Do not abruptly discontinue the medication; sudden cessation can cause adrenal insufficiency.
  • If you miss a dose, take it as soon as possible unless it's close to your next dose. Do not double the dose.
  • Inform your physician if you are scheduled for surgery or experience stress, as dosage adjustments may be necessary.

Proper adherence ensures better disease control and minimizes risks associated with corticosteroid therapy.

Mode of Action DEZCORT 6mg

DEZCORT 6mg works by mimicking the effects of naturally occurring corticosteroids produced by the adrenal glands, influencing various biological pathways.

• Anti-inflammatory Effects:
  • Inhibits the accumulation of inflammatory cells at inflammation sites.
  • Blocks the production of inflammatory mediators like prostaglandins and leukotrienes.
• Immunosuppressive Properties:
  • Suppresses immune system activity by reducing T-cell proliferation and antibody production.
• Metabolic Effects:
  • Impacts carbohydrate, protein, and fat metabolism but to a lesser extent compared to traditional steroids.

By influencing these mechanisms, DEZCORT effectively reduces inflammation, manages immune-mediated conditions, and improves overall clinical outcomes.

DEZCORT 6mg Interactions DEZCORT 6mg

DEZCORT 6mg can interact with a range of other drugs, potentially altering its effects or leading to adverse outcomes.

• Drugs that Reduce DEZCORT Effectiveness:
  • Rifampicin, carbamazepine, phenytoin (enzyme inducers)
• Drugs that Increase DEZCORT Levels:
  • Ketoconazole, itraconazole (CYP3A4 inhibitors)
  • Erythromycin (antibiotic)
• Increased Risk of Side Effects:
  • NSAIDs (e.g., ibuprofen) can increase the risk of gastric ulcers and bleeding.
  • Antidiabetic medications may require dose adjustment as corticosteroids can elevate blood sugar levels.
  • Live vaccines should be avoided due to the risk of disseminated infections.

Always consult your healthcare provider before starting any new medication while taking DEZCORT 6mg.

Dosage of DEZCORT 6mg

The dosing of DEZCORT 6mg must be individualized based on disease severity, patient response, and clinical judgment.

• Standard Adult Doses:
  • Usually initiated at 6mg to 90mg per day, depending on the condition.
  • Maintenance doses are adjusted to the lowest effective level to control symptoms.
• Children:
  • Doses typically calculated per body weight (e.g., 0.25–1.5 mg/kg/day).
• Tapering:
  • Long-term users must taper the dose slowly to avoid adrenal insufficiency.

Dosage changes should only be made under direct medical supervision to ensure safety and efficacy.

Possible side effects of DEZCORT 6mg

Like all corticosteroids, DEZCORT 6mg has potential side effects, particularly with prolonged use or high doses.

• Common Side Effects:
  • Weight gain
  • Increased appetite
  • Facial swelling (moon face)
  • Mood swings, insomnia
• Serious Side Effects:
  • Osteoporosis and bone fractures
  • Suppressed adrenal gland function
  • Elevated blood sugar levels (steroid-induced diabetes)
  • Increased risk of infections
• Rare Side Effects:
  • Psychiatric disturbances (depression, psychosis)
  • Hypertension
  • Ophthalmologic issues (cataracts, glaucoma)

Regular monitoring and appropriate preventive measures can help mitigate these risks during treatment with DEZCORT 6mg.

DEZCORT 6mg Contraindications DEZCORT 6mg

There are specific situations where the use of DEZCORT 6mg is contraindicated due to potential health risks.

• Absolute Contraindications:
  • Known hypersensitivity to Deflazacort or any other corticosteroids
  • Systemic fungal infections
  • Use of live or live-attenuated vaccines during therapy
• Relative Contraindications (Caution Advised):
  • History of severe osteoporosis
  • Active peptic ulcer disease
  • Psychiatric illnesses
  • Uncontrolled diabetes mellitus

Before starting DEZCORT 6mg, a comprehensive medical history evaluation is necessary to prevent complications.

Storage of DEZCORT 6mg

Proper storage ensures that DEZCORT 6mg remains effective until its expiration date.

• Storage Temperature: Keep at 20°C–25°C (68°F–77°F), away from excessive heat and moisture.
• Packaging: Store in the original blister packaging to protect from light and humidity.
• Safety: Keep out of reach of children and pets.
• Handling: Do not use the tablets if the packaging is damaged or if the tablets show signs of discoloration or deterioration.

Following correct storage conditions maintains the safety and effectiveness of DEZCORT 6mg tablets throughout their shelf life.